生物制剂治疗克罗恩病进展

克罗恩病是一种以累及消化道为主的复发性炎性疾病.生物制剂的使用为克罗恩病的治疗提供了新的方向.大量临床研究已证实生物治疗主要是抗TNF α单抗对诱导及维持克罗恩病临床缓解、预防并发症的发生有效.目前临床指南多建议对克罗恩病采取递增方案治疗,对重度患者可及早采取更为有效的包括生物治疗在内的治疗方式,但递减治疗方案在临床中的应用尤其是针对初次诊断者也越来越受到重视.目前早期及长期应用生物治疗的安全性及其是否能改变克罗恩病的自然病程证据尚不充分.应针对患者的不同情况,根据风险/效益研究来确定更合适的治疗方案.     

辩证情绪:研究方法及展望

有关辩证情绪的实证研究已经成为情绪研究中的一个新的热点问题,并从一个本土心理学的研究领域演变为主流心理学的研究课题。辩证情绪是指积极和消极情绪的共存。文章对辩证情绪的研究方法进行了回顾,主要包括辩证情绪研究范式的演变、辩证情绪的诱发方法、辩证情绪的测量方法以及辩证情绪的计算方法,并对不同的研究方法的优缺点及其贡献进行了比较和分析。最后,文章对辩证情绪研究方法的未来发展提出了展望。     

National Survey of Client's Perceptions of Chinese Psychotherapist Practices

The present study is a cross-sectional survey that investigates ethical practices among Chinese psychotherapists from the perspective of a large representative sample of Chinese clients (N?=?1,100). In reports from clients, we found that psychotherapists did poorly in providing informed consent and had other ethical difficulties in the therapeutic setting and with dual relationships. We conclude that Chinese culture, especially Confucianism, had significant impact on the attitudes toward the psychotherapists' ethical practices, which complicated ethical dilemmas. It is important for cross-cultural psychotherapists to become sensitive to the influences of traditional Chinese culture when counseling Chinese clients.     

Dialectical thinking and health behaviors: The effects of theory of planned behavior

The primary purpose of this study was to investigate whether the theory of planned behavior (TPB) mediated the relationship between dialectical thinking and health behaviors. A sample of 285 undergraduates was tested with a dialectical thinking styles scale, health promoting lifestyle profiles, and TPB questionnaires. Structural equation modeling was used for data analysis. Results indicated that all the three dimensions of thinking styles (belief in the connection, acceptance of change, and acceptance of contradiction) exerted significant effects on TPB constructs. Specifically, the connection and the change dimensions had positive effects on health behaviors mediated by TPB, whereas the contradiction dimension had a negative effect. Model 2 showed a satisfactory fit, demonstrating the influential pathways between dialectical thinking and health behaviors. Implications in issues of health promotion and future research are discussed.     

Encoding Processes and Release from Proactive Interference in Short-Term Memory of Preschool Children

A modified proactive interference paradigm was developed to investigate encoding and memory processes in preschool-age children. The buildup and release from proactive interference in preschool-age children parallels that of adults and of mentally retarded persons, indicating that very young children and older people may use many of the same encoding dimensions.     

Brief Sensation Seeking Scale for Chinese – Cultural adaptation and psychometric assessment

International behavioral research requires instruments that are not culturally-biased to assess sensation seeking. In this study we described a culturally adapted version of the Brief Sensation Seeking Scale for Chinese (BSSS-C) and its psychometric characteristics. The adapted scale was assessed using an adult sample (n = 238) with diverse educational and residential backgrounds. The BSSS-C (Cronbach alpha = 0.90) was correlated with the original Brief Sensation Seeking Scale (r = 0.85, p < 0.01) and fitted the four-factor model well (CFI = 0.98, SRMR = 0.03). The scale scores significantly predicted intention to and actual engagement in a number of health risk behaviors, including alcohol consumption, cigarette smoking, and sexual risk behaviors. In conclusion, the BSSS-C has adequate reliability and validity, supporting its utility in China and potential in other developing countries.     

Person perception from changing emotional expressions: primacy,recency, or averaging effect?

ABSTRACT

Dynamic changes in emotional expressions are a valuable source of information in social interactions. As the expressive behaviour of a person changes, the inferences drawn from the behaviour may also change. Here, we test the possibility that dynamic changes in emotional expressions affect person perception in terms of stable trait attributions. Across three experiments, we examined perceivers’ inferences about others’ personality traits from changing emotional expressions. Expressions changed from one emotion (“start emotion”) to another emotion (“end emotion”), allowing us to disentangle potential primacy, recency, and averaging effects. Drawing on three influential models of person perception, we examined perceptions of dominance and affiliation (Experiment 1a), competence and warmth (Experiment 1b), and dominance and trustworthiness (Experiment 2). A strong recency effect was consistently found across all trait judgments, that is, the end emotion of dynamic expressions had a strong impact on trait ratings. Evidence for a primacy effect was also observed (i.e. the information of start emotions was integrated), but less pronounced, and only for trait ratings relating to affiliation, warmth, and trustworthiness. Taken together, these findings suggest that, when making trait judgements about others, observers weigh the most recently displayed emotion in dynamic expressions more heavily than the preceding emotion.     

ON PARADIGM SHIFT IN READING/LITERACY RESEARCH

Abstract

Research is just a set of conventions‐‐the most rigorous way to ask a question and look for answers...research is people-run. And it can be as flexible as the people who run it (Hatch & Farhady, 1982, p. xv).     

How benefits of expressive writing vary as a function of writing instructions,ethnicity and ambivalence over emotional expression

Written emotional disclosure has been reported to confer a variety of benefits on physical and psychological well-being. However, variable findings suggest that outcomes may vary systematically as a function of specific parameters of the experimental design. This study aims to investigate the unique and combined effects of disclosure instructions focusing on emotional expression and instructions facilitating cognitive reappraisal and to examine how ambivalence over emotional expression and ethnicity moderate the effects of these writing instructions. Seventy-one Asian and 59 Caucasian undergraduates (N = 130) with at least minimal physical or depressive symptoms were randomly assigned to one of the four writing conditions: emotional disclosure (ED), cognitive reappraisal (COG), the combination of ED and COG, or a control condition. Self-reported physical symptoms, positive affect (PA) and negative affect were assessed at baseline and three follow-ups spanning 4 months. Mixed linear models revealed that COG writing reduced physical symptoms, ED buffered a decrease in PA over time, and the combination of ED and COG (i.e. self-regulation; SR) was most effective. Asians and highly ambivalent participants benefited most from expressive writing. Findings contribute to the development of a SR moderator model and carry implications for designing expressive disclosure studies, particularly for ethnic minorities.     

Electropulsing-induced strengthening of steel at high temperature

Electropulsing usually promotes a metastable phase to evolve towards its equilibrium state. This work reports an alternative case, where electropulsing promotes the decomposition of the stable δ-phase in duplex stainless steel at high temperature. This decomposition enables both the γ-phase and the σ-phase in the steel to survive and hence to strengthen it at high temperature. The hardness of the quenched sample with electropulsing treatment is 49.4% higher than that without electropulsing treatment. A fundamental understanding of the observation is developed.