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91.
Molecular sequence data, made available in the last 15 years or so, have led to the classification of living cells into three phylogenetic domains: Bacteria, Archaea, and Eucarya. All the organisms that have been tested belonging to either domain were capable of mounting a stress response with essentially the same characteristics, regardless of the stressor. The protagonists in the cell's stress response are the stress genes and their protein products. Some of the latter are molecular chaperones. Under physiological conditions, these chaperones aid other cellular proteins to fold properly and achieve a native -functional- configuration, and to translocate from the place of synthesis to the cell's locale in which they will operate. In a stressed cell, the stress proteins that are chaperones protect other molecules from denaturation and help those partially damaged to regain a functional configuration. Thus, cell death is avoided and recovery is enhanced. The study of stress genes and proteins has progressed considerably in organisms belonging to the domains Bacteria and Eucarya. Less is known about the archaeal stress genes. Here, research with an organism from the Archaea is discussed, focusing on the stress genes of the hsp70 (dnaK) locus. Future perspectives for basic and applied research within the health sciences and biotechnology industries are presented. 相似文献
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93.
This article presents research in which the Five Factor Model of personality was tested as a predictor of job performance. 125 financial services managers who had enrolled in a potential evaluation programme were given the NEO-FFI, a questionnaire designed for measuring the Big Five. Job performance was assessed using nine rating scales and they were grouped into two components: job problem-solving ability and job motivation. Also, one single scale for measuring global job performance was used. The results show that Neuroticism and Conscientiousness correlated with the two components and with the global measure of job performance. Extraversion, Openness and Agreeableness are correlated with one facet or with the global rating of job performance. Taken together, the results suggest that the Five Factor Model is a valid predictor of job performance. The implications of the results for practice and future research are discussed. 相似文献
94.
Most concepts of development explain certain behavior changes as products or markers of the invariable succession of emerging periods, stages, refinements, or achievements that define and order much of an individual's life. A different but comparable concept can be derived from the most basic mechanisms of behavior analysis, which are its environmental contingencies, and from its most basic strategy, which is to study behavior as its subject matter. From a behavior-analytic perspective, the most fundamental developmental questions are (a) whether these contingencies vary in any systematic way across the life span, and thus make behavior change in a correspondingly systematic way; and (b) whether some of these contingencies and their changes have more far-reaching consequences than others, in terms of the importance to the organism and others, of the behavior classes they change. Certain behavior changes open the door to especially broad or especially important further behavior change, leading to the concept of the behavioral cusp. A behavioral cusp, then, is any behavior change that brings the organism's behavior into contact with new contingencies that have even more far-reaching consequences. Of all the environmental contingencies that change or maintain behavior, those that accomplish cusps are developmental. Behavior change remains the fundamental phenomenon of development for a behavior-analytic view; a cusp is a special instance of behavior change, a change crucial to what can come next. 相似文献
95.
Single-route models attribute stimulus-response compatibility effects to the difficulty of translation from stimulus to response. Dual-route models propose that compatibility effects reflect in part an additional direct, or automatic, activation route. Selected findings from three lines of research are reported that converge to provide evidence consistent with the view that the automatic activation route plays a role in compatibility effects. The data suggest that the activation produced via this route by relevant stimulus attributes influences response selection only when all mappings of stimuli to responses are known to be compatible. 相似文献
96.
W. M. de Muynck 《Synthese》1995,102(2):293-318
The axiomatic approaches of quantum mechanics and relativity theory are compared with approaches in which the theories are thought to describe readings of certain measurement operations. The usual axioms are shown to correspond with classes of ideal measurements. The necessity is discussed of generalizing the formalisms of both quantum mechanics and relativity theory so as to encompass more realistic nonideal measurements. It is argued that this generalization favours an empiricist interpretation of the mathematical formalisms over a realist one. 相似文献
97.
Letícia M. Sicuro Corrêa 《Journal of psycholinguistic research》1995,24(3):183-203
Methodological difficulties are identified in the assessment of children's comprehension of relative clauses (RCs) by means of the standard acting-out procedure. An alternative experimental task is proposed which attempts to minimize these difficulties while exploring the advantages of the acting-out technique. An experiment is reported in which Portuguese-speaking 3- to 6-year olds were tested by means of this alternative task. The results show children being affected by both the position and the focus of the RC in the same way adults have been reported to be and an error analysis suggests that most of children's difficulties can be ascribed to memory overload while RCs are processed as noun modifier sentences. These results contradict the view that there are developmental differences with regard to the way sentences with RCs are parsed and that processing load induces errors particularly manifested in right-branching subject focus sentences. Developmental changes taking place between the ages of 3 and 6 are considered and questions are raised concerning development from the age of 5.The research reported here was carried out while the author read for the PhD degree at the University of London. The writing up of this paper was financially supported by a postdoctoral grant from the Brazilian Research Council (CNPq: 302103-86.4). 相似文献
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对先秦道家学派的创始人及主要代表─-老子和庄子的人格心理学思想进行了比较,认为其相同点有九,相异点有三;并力求以辨正唯物主义和历史唯物主义为利器,透过历史的重重雾障,对之作出较合理的客观评价,以便于古为今用。 相似文献
100.