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Youth with disabilities face many challenges in life which are thought to have a negative impact on their well-being. Evidence, however, suggests that individuals differ in their resilience to deal with adverse life-events and protect their well-being. These differences may be explained by an individual’s resources such as education, employment, and social support. Studies on how youth with disabilities perceive their well-being and resources important to their well-being are, however, lacking. In this study we therefore compared education, employment, social support, and well-being between youth with disabilities (n?=?120) and their peers (n?=?117) in South Africa. In addition, we investigated the relationship between background characteristics, having a disability, access to resources, and well-being. The unemployment rate among youth with disabilities is higher, they are less educated, receive less social support and report poorer states of well-being. Our study showed that having a disability, social support, and employment were associated with the well-being of youth in South Africa. While having a disability predicted well-being in youth, the effect was mediated by employment and social support, indicating that those two resources influence wellbeing through both a direct and buffer effect. Therefore, employment and social support may mitigate the negative consequences of a disability and have a substantial role in improving or maintaining well-being.  相似文献   
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Journal of Philosophical Logic - We present an elementary system of axioms for the geometry of Minkowski spacetime. It strikes a balance between a simple and streamlined set of axioms and the...  相似文献   
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Emotional processing in bipolar disorder (BD) entails a complex attentional pattern not merely restricted to happy or sad biases, but also directed towards threatening information. This study examined threat-related bias on attentional orienting when participants were not instructed about the presentation of emotional stimuli (i.e., implicit instructions). An emotional dot-probe task in which an emotional face (i.e., threat, sad, happy) is simultaneously displayed with a neutral face was applied to BD individuals in their different episodes: mania (n?=?26), depression (n?=?24), and euthymia (n?=?28) as well as to a group of healthy controls (n?=?28). Symptomatic BD patients (i.e., in a manic or depressive episode) showed an attentional orienting bias toward threatening faces but not for happy or sad faces, while euthymic BD patients did not exhibit any attentional bias for emotional stimuli. A bias toward happy faces was found in the control group. Threat-related bias was not related to the severity of affective and anxiety symptoms in BD. When attention is not explicitly directed to emotional information, threat-related bias may characterize attentional orienting during mania and depression, but may be attenuated during euthymia.

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A significant challenge for understanding alcoholism lies in discovering why some, but not other individuals, become dependent on alcohol. Genetic, environmental, cultural, developmental, and neurobiological influences are recognized as essential factors underlying a person's risk for becoming alcohol dependent (AD); however, the neurobiological processes that trigger this vulnerability are still poorly understood. Hormones are important in the regulation of many functions and several hormones are strongly associated with alcohol use. While medical consequences are important, the primary focus of this review is on the underlying confluence of appetitive/feeding, reproductive and posterior pituitary hormones associated with distinct phases of alcoholism or assessed by alcohol craving in humans. While these hormones are of diverse origin, the involvement with alcoholism by these hormone systems is unmistakable, and demonstrates the complexity of interactions with alcohol and the difficulty of successfully pursuing effective treatments. Whether alcohol associated changes in the activity of certain hormones are the result of alcohol use or are the result of an underlying predisposition for alcoholism, or a combination of both, is currently of great scientific interest. The evidence we present in this review suggests that appetitive hormones may be markers as they appear involved in alcohol dependence and craving, that reproductive hormones provide an example of the consequences of drinking and are affected by alcohol, and that posterior pituitary hormones have potential for being targets for treatment. A better understanding of the nature of these associations may contribute to diagnosing and more comprehensively treating alcoholism. Pharmacotherapies that take advantage of our new understanding of hormones, their receptors, or their potential relationship to craving may shed light on the treatment of this disorder.  相似文献   
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Emotion processing impairments are common in patients undergoing brain surgery for fronto-temporal tumour resection, with potential consequences on social interactions. However, evidence is controversial concerning side and site of lesions causing such deficits. This study investigates visual and auditory emotion recognition in brain tumour patients with the aim of clarifying which lesion sites are related to impairments in emotion processing from different modalities. Thirty-four patients were evaluated, before and after surgery, on facial expression and emotional prosody recognition; voxel-based lesion–symptom mapping (VLSM) analyses were performed on patients’ post-surgery MRI images. Results showed that patients’ performance decreased after surgery in both visual and auditory modalities, but, in general, recovered 3 months after surgery. In facial expression recognition, left brain-damaged patients showed greater post-surgery deterioration than right brain-damaged ones, whose performance specifically decreased for sadness and fear. VLSM analysis revealed two segregated areas in the left hemisphere accounting for post-surgery scores for happy (fronto-temporo-insular region) and surprised (middle frontal gyrus and inferior fronto-occipital fasciculus) facial expressions. Our findings demonstrate that surgical removal of tumours in the fronto-temporal region produces impairment in facial emotion recognition with an overall recovery at 3 months, suggesting a partially different representation of positive and negative emotions in the left and right hemispheres for visually – but not auditory – presented emotions; moreover, we show that deficits in specific expression recognition are associated with discrete lesion locations.  相似文献   
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We propose a method for controlling acquiescent response in which acquiescence response variance is isolated in an independent factor. This kind of procedure is available for perfectly balanced scales (i.e. half of the items are worded in the opposite direction to the other half with respect to a general trait). However, few questionnaires are designed so that exactly half of the items are worded in this way. If this is not the case, the available methods are useless. We propose to adapt the rotation method of Lorenzo‐Seva and Rodríguez‐Fornells to handle partially balanced scales (i.e. only a few items in the scale are worded in the opposite direction). The most important characteristic of our method is that it removes the variance due to acquiescent response from all the items in the questionnaire (i.e. the balanced subset of items, but also the unbalanced subsets of items). The usefulness of the method is illustrated in a numerical example.  相似文献   
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