P3b反映基于相似性的图形类别归纳决策过程(309)

先前关于归纳推理的研究没有探讨过图形类别归纳任务中决策过程的事件相关电位(ERPs)特征。该研究采用图形材料,通过记录和分析图形类别归纳推理任务的结论评估阶段的脑电信号,探讨了不同类别条件下图形归纳推理决策过程的ERP特征。实验结果显示,推理决策过程中,当前提为一些狗具有某种属性特征时,结论一致类别(狗类及马类)比结论不一致类别下(椅子类)的归纳推理诱发了更大的P3b的波幅; 而结论一致类别下,类别内(狗类)比类别外(马类)推理诱发更大的后部脑区的P3b的波幅,反映了相似性对类别归纳的贡献。该研究为理解类别归纳过程的决策阶段的动态加工过程提供了神经电生理学证据。研究结果进一步支持了类别归纳的相似性理论模型。     

Women’s Understanding and Attitudes towards Down Syndrome and Other Genetic Conditions in the Context of Prenatal Screening

In order to explore the impact of potential new technologies in the area of prenatal screening, we conducted a baseline study using qualitative interviews to explore women’s attitudes and knowledge regarding current and future prenatal screening technology and methods. Three cohorts were interviewed, including healthy women without children, healthy women with healthy children, and healthy women with children who have de novo genetic disorders. This study aimed to assess the baseline understanding and attitudes of women in Western Australia. Women from each cohort demonstrated adequate knowledge of the differences between screening and diagnostic tests, but were mostly unaware of the conditions for which screening is currently available except Down syndrome. Women who had children with de novo genetic conditions were generally aware of more genetic conditions than women with or without healthy children. Most women recognised the genetic basis for the conditions mentioned. Two thirds of women understood that Down syndrome is a chromosomal condition; just one third recognised that the phenotype is variable. Most women expressed a positive attitude towards Down syndrome. Social acceptance of children with Down syndrome was commonly mentioned as a concern. While the majority of women with children supported screening for Down syndrome, they emphasised that it must be an autonomous choice. General knowledge of genetic conditions illustrated that women are exposed to diverse conditions from lived experience as well as the media.     

Site visits in interfaith and religious studies pedagogy: Reflections on visiting a Hindu temple in central Pennsylvania

Site visits provide an irreplaceable learning experience to students in both religious studies and the emerging field of interfaith studies. The conceptual core of this thesis is the claim, drawn from feminist epistemology, that an embodied pedagogy – a pedagogy which engages students not only intellectually, but as embodied beings who inhabit a space, engage in physical activities, and undergo various sensory experiences – is ultimately more enriching than a pedagogy centered exclusively in the classroom. Factors that make a site visit a successful instance of embodied pedagogy include the provision of sufficient context to students in advance for them to understand and appreciate the experience, an opportunity afterward to reflect on this experience in an intentional way, ensuring the site and the community whose space it is are treated with proper respect, and ensuring that the religious sensibilities of one's students are also similarly respected.     

Thinking Developmentally: Perspectives Following Loewald and Klein

In this article, I explore two perspectives on development that are central to how I think and work as an analyst, one drawn from the work of Hans Loewald and one from Melanie Klein. Loewald turned the usual psychoanalytic way of thinking, rooted in the past, on its head when he theorized that development proceeds by internalization of the parent’s future vision of the child and, by corollary, the analyst’s future vision of the patient. Using a vignette from Klein’s work with 10-year-old Richard, I show how the analyst’s image of the patient’s potential can facilitate growth and development. Melanie Klein also introduced a radical reordering of traditional psychoanalytic theory when she theorized that the mind develops and is structured as positions, not as successive phases. For Klein, the mind is organized in groupings of anxieties, defenses, and object-relations that are in a continuous state of oscillation throughout life independent of chronological age. Through a clinical vignette, I illustrate how one understands a patient differently when development is seen as occuring in momentary shifts between different levels of the personality rather than as stages over time.     

靶向药物不良反应的认识与思考

新的靶向药物出现提高了抗癌疗效,降低了毒性,使转移性恶性肿瘤患者从治疗中获益。靶向药物耐受性好,通常出现轻微或中度的毒副反应。尽管大多数不良反应是可以得到迅速处理的,但是严重的甚至危及生命的不良反应仍能够发生。因此,为更好地指导临床实践工作,该文综述了实体瘤治疗中常用靶向药物的主要不良反应和安全数据,并按照药物的作用靶...     

Chained and tandem scheduling with children

Children 4 to 7 yr in age were reinforced with trinkets and pennies on chained and tandem schedules. The schedules used were chain DRL FR, chain DRO FR, chain FI FR, tand FI FR, and tand DRO FR. Chain DRL FR and chain DRO FR schedules almost always produced strong schedule and stimulus control, but chain FI FR schedules rarely did if additional techniques were not used. Strong control was produced with chain FI FR schedules, however, if: (a) the FR component was increased in size; (b) schedule and stimulus control was first established with chain DRL FR or chain DRO FR schedules before shifting to the chain FI FR; or (c) an external clock was attached to the FI. Tand FI FR schedules never produced regular or repeatable patterns of responding when additional procedures were not used. Rate patterns resembling those of chain FI FR schedules were produced by tand FI FR schedules, however, if: (a) an external clock was attached to the FI component or (b) control was established by means of tand DRO FR schedules before the tand FI FR was used. Stimulus control was found to be exercised by specific visual stimuli, change of stimuli, and schedule order. Control exercised by schedule order was probably mediated by the child's own behavior which had assumed discriminative stimulus properties.     

Aging and the perception of biological motion

Two experiments examined how observers' ability to perceive biological motion changes with increasing age. The observers discriminated among kinetic figures, depicting walking, jogging, and skipping. The direction, duration, and temporal correspondence of the motions were manipulated. Quantitative differences occurred between the recognition performances of younger and older observers, but these differences were often modest. The older and younger observers' performances were comparable for most conditions at stimulus durations of 400 ms. The older observers also performed well above chance at shorter durations of 240 and 120 ms. Unlike their performance on other 2- or 3-dimensional motion tasks, older observers' ability to perceive biological motion is relatively well preserved.     

TRAINING AND GENERALIZATION OF SEXUAL ABUSE PREVENTION SKILLS FOR WOMEN WITH MENTAL RETARDATION

Previous research has shown that behavioral skills training to teach sexual abuse prevention skills to women with mental retardation results in skill acquisition but poor generalization. In this investigation we evaluated procedures for enhancing generalization following training. Five women with mental retardation received 10 behavioral skills training sessions followed by in situ training when the skills did not fully generalize. Behavioral skills training resulted in skill acquisition and in situ training produced generalized responding during naturalistic assessments.