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71.
72.
Simeoni S Biselli R D'Amelio R Rocca B Lattanzio S Mucci L Davì G Patacchioli FR 《Stress (Amsterdam, Netherlands)》2011,14(3):282-289
Few studies have assessed the effects of stress on in vivo platelet activation. In the present study, hypobaric hypoxia induced by rapid decompression during high-altitude simulated flight in a hypobaric chamber was used to evaluate the effects of environmental stress on salivary cortisol and urinary thromboxane metabolite (TXM) excretion, a noninvasive marker of in vivo platelet function. Twenty-one male aviators (mean ± SD age = 36 ± 7 years) experiencing hypoxia by removing their oxygen mask for 4-5 min during a simulated flight to 25,000 ft (7,620 m; pO(2) = 59.17 mmHg) and a matched control group of thirteen flying instructors wearing oxygen masks during the challenge, were studied. Hypobaric hypoxia induced a transient significant increase (P < 0.001) in the aviators' salivary cortisol concentration; the overall pattern of diurnal cortisol fluctuation was maintained in both groups. Urinary TXM showed a significant ~30% reduction (P < 0.01) after the chamber session in aviators exposed to hypobaric hypoxia, but not in controls. A significant inverse correlation was found between salivary cortisol and urinary TXM in aviators (r = - 0.64, P = 0.0015). Salivary cortisol was a significant predictor (P < 0.001) for urinary TXM concentrations in aviators. In conclusion, here we observed that an acute stress-induced salivary cortisol increase was associated with reduced urinary thromboxane biosynthesis, providing the first indirect evidence for an inhibitory effect of acute stress on in vivo platelet function. 相似文献
73.
Mild cognitive impairment (MCI) is a heterogeneous condition characterized by the presence in an otherwise healthy elderly
individual of cognitive deficits involving specific domains in the absence of significant functional impairments. Reports
indicate that prospective memory (PM), that is, the ability to remember to execute delayed intentions, is impaired in individuals
with MCI. The present review discusses the current debate in the literature on PM functioning in MCI by focusing on the relationship
between prospective retrieval and retrospective memory functioning. Analysis of the reported evidence revealed that both the
prospective component and the retrospective component of PM can be impaired in MCI. Declarative memory dysfunction may account
for the retrospective memory impairment, while either reduced executive abilities or a deficit of reflexive mechanisms could
explain the prospective component impairment. 相似文献
74.
In three experiments, we tested the hypothesis that activation of multiplication operand nodes (e.g., 3 and 8) can occur through presentation of their product (e.g., 24). In Experiments 1 and 2 we found activation of the operands when the product was presented as a cue in a number-matching task. In Experiment 3, activation also occurred in a parity-matching task, where the product (24) was not relevant to the parity matching on its operands (3 and 8). We concluded that bidirectional links exist among the operands and their product for multiplication problems and these links can be activated in a purely stimulus-driven manner. We suggest this may constitute the basis for the solution of simple divisions by mediation through the complementary multiplication facts. 相似文献
75.
Neuropsychological investigation of the development of the mnesic function in mental retardation has primarily focused on evaluating short-term memory (STM). Studies have often documented a reduced verbal short-term memory span in individuals with mental retardation and with Down syndrome in particular, compared to groups of mental age-matched controls. However, recent evidence suggests that verbal short-term memory is not equally impaired in all individuals with mental retardation. Findings in children with Williams syndrome are particularly relevant in this regard. Also, data concerning STM for visual information suggest that visual-object and visual-spatial working memory may be differently compromised in people with mental retardation. In particular, individuals with Williams syndrome exhibit specific difficulties in visual-spatial but not in visual-object working memory tasks compared to typically-developing children matched for mental age. Instead, people with Down syndrome show reduced performance in both visual-spatial and visual-object tests. Taken together, these results reinforce the view that intellectual disability is not a unitary condition characterized by homogeneous slowness of cognitive development but a variety of conditions in which some cognitive functions may be more disrupted than others. The finding that the working memory deficit in individuals with Williams and Down syndrome may be qualitatively differentiated also supports the hypothesis that it is not simply a manifestation of general cognitive impairment but, rather, the expression of a specific deficit of a discrete cognitive ability. 相似文献
76.
Recent evidence has shown that uninformative numbers can trigger attention shifts congruent with the spatial representation
of number magnitude (Fischer, Castel, Dodd, & Pratt, 2003). In the present study, three spatial-cuing experiments whose aim
was to qualify the automaticity of this numbermediated orienting are described. Experiment 1 replicated the phenomenon, showing
that uninformative numbers can evoke orienting in a simple detection task. In Experiment 2, target location was random, but
the participants were encouraged to shift attention to the left in response to large numbers and to the right in response
to small numbers. No evidence for strong automaticity was observed, since the participants’ performance was better when left-side
targets were preceded by large numbers than when they were preceded by small numbers and vice versa. Experiment 3 corroborated
this pattern by comparing gaze- and number-mediated cuing under conditions of real counterpredictiveness. The results indicate
that unlike gaze-driven orienting, number-mediated orienting is not obligatory. 相似文献
77.
This paper reviews different approaches for explaining body sway while quiet standing that directly address the instability of the human inverted pendulum. We argue that both stiffness control [Winter, D. A., Patla, A. E., Riedtyk, S., & Ishac, M. (2001). Ankle muscle stiffness in the control of balance during quiet standing. Journal of Neurophysiology, 85, 2630-2633] and continuous feedback control by means of a PID (Proportional, Integral, Derivative) mechanism [Peterka, R. J. (2000). Postural control model interpretation of stabilogram diffusion analysis. Biological Cybernetics, 83, 335-343.] can guarantee asymptotic stability of controlled posture at the expense of unrealistic assumptions: the level of intrinsic muscle stiffness in the former case, and the level of background noise in the latter, which also determines an unrealistic level of jerkiness in the sway. We show that the decomposition of the control action into a slow and a fast component (rambling and trembling, respectively, as proposed by [Zatsiorsky, V. M., & Duarte, M. (1999). Instant equilibrium point and its migration in standing tasks: Rambling and trembling components of the stabilogram. Motor Control, 4, 185-200; Zatsiorsky, V. M., & Duarte, M. (2000). Rambling and trembling in quiet standing. Motor Control, 4, 185-200.]) is useful but must be modified in order to take into account that rambling is not a stable equilibrium trajectory. We address the possibility of a form of stability weaker than asymptotic stability in light of the intermittent stabilization mechanism outlined by [Loram, I. D., & Lakie, M. (2002a). Human balancing of an inverted pendulum: position control by small, ballistic-like, throw and catch movements. Journal of Physiology, 540, 1111-1124.], and propose an indicator of intermittent stabilization that is related to the phase portrait of the human inverted pendulum. This indicator provides a further argument against the plausibility of PID-like control mechanisms. Finally, we draw attention to the sliding mode control theory that provides a useful theoretical framework for formulating realistic intermittent, stabilization models. 相似文献
78.
The perception of luminosity is thought to depend upon the intensity of the stimulus: a surface begins to appear self-luminous when it emits or reflects a certain amount of light. This is known as the luminosity threshold. It is a common opinion among vision scientists that such a threshold is correlated to the intensity of a perceptually white surface, in the sense that only an area of the visual field with luminance higher than perceived surface-white will appear luminous. Here we show grey colours that appear luminous in virtue of surrounding luminance ramps. These ramps are intended to mimic halos seen around light sources in natural environments. The results of three experiments indicate that the phenomenon is in direct contradiction to the aforementioned assumptions and suggest the existence of separate perceptual pathways for self-luminosity perception and for surface-colour perception. 相似文献
79.
The hypothesis that the sex composition of an applicant pool affects the hiring probabilities of individual job applicants was tested using gender-distinctive information on accepted and rejected job applicants in The Netherlands. The evidence supports this hypothesis, although the effect sizes are moderate. Both men and women have a lower probability of being hired when the applicant pool contains fewer applicants from their own sex. 相似文献
80.
Ottoboni G Tessari A Cubelli R Umiltà C 《Journal of experimental psychology. Human perception and performance》2005,31(4):778-789
The authors used a modified Simon task (J. R. Simon, 1969) to assess the automatic recognition of handedness. Participants responded to the color of a circle in the center of the photograph of a right or a left hand, displayed in the center of the computer screen. A regular Simon effect was found for back views, whereas a reverse Simon effect was found for palm views. This pattern of results was found when the forearm was present (Experiment 2), when 1 finger at a time was rendered invisible (Experiment 3), and when the hands were connected to a body image (Experiment 4). When the hands were cut at the wrist, no effect emerged (Experiment 1). These findings suggest an automatic encoding of the relative position of the hand in relation to the body (imaginary or real) rather than the automatic encoding of handedness. 相似文献