Modulation of N400 in chronic non-fluent aphasia using low frequency Repetitive Transcranial Magnetic Stimulation (rTMS)

Low frequency Repetitive Transcranial Magnetic Stimulation (rTMS) has previously been applied to language homologues in non-fluent populations of persons with aphasia yielding significant improvements in behavioral language function up to 43 months post stimulation. The present study aimed to investigate the electrophysiological correlates associated with the application of rTMS through measurement of the semantic based N400 Event-related brain potentials (ERP) component. Low frequency (1 Hz) rTMS was applied to the anterior portion of the homologue to Broca’s area (pars triangularis), for 20 min per day for 10 days, using a stereotactic neuronavigational system. Twelve non-fluent persons with aphasia, 2-6 years post stroke were stimulated. Six participants were randomly assigned to receive real stimulation and six participants were randomly assigned to receive a blind sham control condition. ERP measures were recorded at baseline, 1 week and 2 months subsequent to stimulation. The findings demonstrate treatment related changes observed in the stimulation group when compared to the placebo control group at 2 months post stimulation indicating neuromodulation of N400 as a result of rTMS. No treatment related changes were identified in the stimulation group, when compared to the sham group from baseline to 1 week post stimulation. The electrophysiological results represent the capacity of rTMS to modulate neural language networks and measures of lexical-semantic function in participants with non-fluent aphasia and suggest that time may be an important factor in brain reorganization subsequent to rTMS.     

In Their Footsteps or Shadow? Gender Differences in Choosing a STEM Major as a Function of Sibling Configuration and Older Sibling’s Gender and Math Ability

Although the association between siblings’ compositional characteristics and educational performance has been extensively studied, the question of whether the features of a sibling group are related to substantive gendered educational preferences has not been examined. Our analysis of the National Longitudinal Survey of Youth 1979 cohort (NLSY-79) Mothers and Children Files (N?=?1545; 57% young women; 22% STEM major) showed that siblings’ compositional characteristics matter for STEM major preferences in college, but only for young women. Our findings indicated that women were more likely to prefer a STEM major if they were raised in smaller sibling groups, in male sibling group dominance, and if they had an older sister with high math achievement. These results are in line with the resource dilution approach; they shed light on the effects of being in a normative male-role sibling group climate; and they suggest that gendered outcomes are shaped by the interplay of role modeling and same-gender competitive stimulation. We also found that for young men, their preference for majoring in a STEM field was mostly driven by their own math ability. These findings suggest that socialization experiences that operate on the sibling level play a crucial role in whether girls become interested in and pursue “gender-atypical” educational choices. Our findings also underscore the need to differentiate these theoretical approaches by gender, particularly when applied to gendered outcomes such as STEM career trajectories.

     

The stigmatized perceiver: Exploring the implications of social stigma for cross-race face processing and memory

The human face is an important source of information, such as race or ethnicity, which can guide social interaction and outcomes. Research suggests that compared to majority and dominant group members, minority and subordinate group members tend to experience chronic stigma, resulting in more negative life outcomes (e.g., educational and occupational attainment). We argue that theory and research exploring face perception has not led to models that incorporate how the chronic experience of stigma may impact judgments, reflecting a gap with potential consequences for the validity and generalizability of the theories developed. We propose a framework for understanding how experiencing a socially stigmatized racial identity may lead perceivers to engage in face processing differently from their non-stigmatized counterparts. With a focus on the literature examining the cross-race effect, we explore the potential impact of chronic social stigma on three theorized moderators guiding processing and memory for same-versus cross-race faces. Our analysis suggests that future research focusing on stigmatized perceivers could help to explain some variation in findings, lead to novel theoretical development, and ultimately produce more generalizable research across several domains of inquiry.     

Religious Bias Among Religiously Conscious Black Christians in the United States

Research with White participants has demonstrated religious intergroup bias; however, religious identity may be different for Black Americans. Only religiously conscious Black Christians demonstrated a preference for Christian targets over Muslim and Atheist targets. Future research should consider what factors result in a person becoming conscious of other's religion.     

Objectivity and a comparison of methodological scenario approaches for climate change research

Climate change assessments rely upon scenarios of socioeconomic developments to conceptualize alternative outcomes for global greenhouse gas emissions. These are used in conjunction with climate models to make projections of future climate. Specifically, the estimations of greenhouse gas emissions based on socioeconomic scenarios constrain climate models in their outcomes of temperatures, precipitation, etc. Traditionally, the fundamental logic of the socioeconomic scenarios—that is, the logic that makes them plausible—is developed and prioritized using methods that are very subjective. This introduces a fundamental challenge for climate change assessment: The veracity of projections of future climate currently rests on subjective ground. We elaborate on these subjective aspects of scenarios in climate change research. We then consider an alternative method for developing scenarios, a systems dynamics approach called ‘Cross-Impact Balance’ (CIB) analysis. We discuss notions of ‘objective’ and ‘objectivity’ as criteria for distinguishing appropriate scenario methods for climate change research. We distinguish seven distinct meanings of ‘objective,’ and demonstrate that CIB analysis is more objective than traditional subjective approaches. However, we also consider criticisms concerning which of the seven meanings of ‘objective’ are appropriate for scenario work. Finally, we arrive at conclusions regarding which meanings of ‘objective’ and ‘objectivity’ are relevant for climate change research. Because scientific assessments uncover knowledge relevant to the responses of a real, independently existing climate system, this requires scenario methodologies employed in such studies to also uphold the seven meanings of ‘objective’ and ‘objectivity.’     

Infant behaviors influence mothers’ provision of responsive and directive behaviors

Mother–infant interactions are important to infant development because they are predictive of infants’ social, cognitive, and language development (0070 and 0150). Because maternal responsive and directive behaviors are associated with differential infant outcomes, it is important to investigate influences on mothers’ provision of responsive and directive behaviors. Yet, the dyadic interaction literature is predominantly unidirectional from maternal behavior to infant outcomes. Therefore, the current study examined infant initiating behaviors and consequent maternal responses in a sample of 26 13-month-old infants and their mothers, videotaped during 5 min of free-play. Findings revealed that infants produced a variety of initiatives, and that these different infant initiatives prompted differential patterns of maternal responsive versus directive behaviors. Further, results of analyses of divergent types of maternal directive behaviors – Responsive Directives, ReDirectives, and Intrusive Directives – also may help clarify major discrepancies in the current literature regarding the positive and negative effects of maternal directiveness.     

Loss Aversion,Intellectual Inertia,and a Call for a More Contrarian Science: A Reply to Simonson & Kivetz and Higgins & Liberman

Higgins and Liberman (2018) and Simonson and Kivetz (2018) offer scholarly and stimulating perspectives on loss aversion and the implications for the sociology of science of its acceptance as a virtual law of nature. In our view, Higgins and Liberman (2018) largely complement our conclusion that the empirical evidence does not support loss aversion. Moreover, in alignment with our call for a contextualized perspective, they provide an excellent discourse on how a more nuanced view of reference points and consumers’ regulatory focus enriches our understanding of the psychological impact of losses and gains. Simonson and Kivetz (2018) approached our perspective with skepticism, and, while they retain some skepticism, they express agreement on the larger point that loss aversion has been accepted too uncritically. Both commentaries point to a need for a critical reevaluation of prevailing paradigms. Here, we build on these perspectives, as well as our experience working on the topic of loss aversion, to call for structural changes to facilitate scholarly debate on science's status quo.     

fMRI of parents of children with Asperger Syndrome: a pilot study

BACKGROUND: People with autism or Asperger Syndrome (AS) show altered patterns of brain activity during visual search and emotion recognition tasks. Autism and AS are genetic conditions and parents may show the 'broader autism phenotype.' AIMS: (1) To test if parents of children with AS show atypical brain activity during a visual search and an empathy task; (2) to test for sex differences during these tasks at the neural level; (3) to test if parents of children with autism are hyper-masculinized, as might be predicted by the 'extreme male brain' theory. METHOD: We used fMRI during a visual search task (the Embedded Figures Test (EFT)) and an emotion recognition test (the 'Reading the Mind in the Eyes' (or Eyes) test). SAMPLE: Twelve parents of children with AS, vs. 12 sex-matched controls. DESIGN: Factorial analysis was used to map main effects of sex, group (parents vs. controls), and sexxgroup interaction on brain function. An ordinal ANOVA also tested for regions of brain activity where females>males>fathers=mothers, to test for parental hyper-masculinization. RESULTS ON EFT TASK: Female controls showed more activity in extrastriate cortex than male controls, and both mothers and fathers showed even less activity in this area than sex-matched controls. There were no differences in group activation between mothers and fathers of children with AS. The ordinal ANOVA identified two specific regions in visual cortex (right and left, respectively) that showed the pattern Females>Males>Fathers=Mothers, both in BA 19. RESULTS ON EYES TASK: Male controls showed more activity in the left inferior frontal gyrus than female controls, and both mothers and fathers showed even more activity in this area compared to sex-matched controls. Female controls showed greater bilateral inferior frontal activation than males. This was not seen when comparing mothers to males, or mothers to fathers. The ordinal ANOVA identified two specific regions that showed the pattern Females>Males>Mothers=Fathers: left medial temporal gyrus (BA 21) and left dorsolateral prefrontal cortex (BA 44). CONCLUSIONS: Parents of children with AS show atypical brain function during both visual search and emotion recognition, in the direction of hyper-masculinization of the brain. Because of the small sample size, and lack of age-matching between parents and controls, such results constitute a pilot study that needs replicating with larger samples.     

Relationships Among Perceived Racial Stress, Intolerance of Uncertainty, and Worry in a Black Sample

The purpose of this study was to explore the relationships among chronic worry, perceived racial stress, and intolerance of uncertainty in a sample of adults who racially identify as Black. Intolerance of uncertainty has been associated with worry and generalized anxiety disorder in predominantly White samples. Given that racial stress is likely to increase worry, perhaps through the mechanism of intolerance of uncertainty, intolerance of uncertainty was hypothesized to mediate the relationship between perceived racial stress and chronic worry. A nonclinical sample of 77 Black undergraduate students at an urban university completed a series of questionnaires assessing the constructs of interest. Both perceived racial stress and intolerance of uncertainty were significantly correlated with chronic worry in this sample. Moreover, intolerance of uncertainty fully mediated the relationship between perceived racial stress and worry for these Black individuals. These findings are discussed in terms of directions for future research and implications for clinical interventions for Black individuals who are both exposed to racial stress and suffer from chronic worry.     

Doubting one’s doubt: A formula for confidence?

People feel, think, and act differently when doubt rather than confidence is accessible. A traditional perspective on the accessibility of doubt holds that multiple sources of doubt activation should lead to increased levels of uncertainty. In contrast, we find that under some conditions two sequential sources of doubt activation result in decreased levels of uncertainty. We suggest that this follows from a meta-cognitive process in which people come to “doubt their doubt.” In Study 1, individuals with chronically accessible uncertainty who were further exposed to an uncertainty manipulation paradoxically reported reduced uncertainty. In Study 2, participants were first primed with doubt or certainty and then exposed to a manipulation associated with either confidence (i.e., head nodding) or doubt (head shaking). Supporting the idea that people can either trust or doubt their own doubts, head nodding (vs. shaking) accentuated (vs. attenuated) the impact of the initial doubt vs. certainty manipulation. These findings advance the literature on meta-cognition, self-doubt, and embodiment, and may have clinical applications.