Electrolytic lesions of the medial prefrontal cortex do not interfere with long-term memory of extinction of conditioned fear

Lesion studies indicate that rats without the medial prefrontal cortex (mPFC) have difficulty recalling fear extinction acquired the previous day. Several electrophysiological studies have also supported this observation by demonstrating that extinction-related increases in neuronal activity in the mPFC participate in expression of fear extinction. However, a more recent study has shown that fear extinction can be recalled, in certain circumstances, without mPFC potentiation, suggesting contribution of other circuits. Here, we examined this possibility in rats that were subjected to auditory fear conditioning, extinction training, and extinction retention test 7 d later. Electrolytic lesions were made in the mPFC, the motor cortex (MO), the dorsal septum (SEP), or the mediodorsal thalamus (MD), because of their potential participation in conditioned fear inhibition; combined lesions including the mPFC with the MO, SEP, or MD were also made. The lesions were made either 1 wk before conditioning or 1 d after extinction training. All rats normally extinguished their conditioned freezing behavior during extinction training and did not display any return of this behavior during the retention test. These data reveal that the mPFC is not required for the acquisition, the expression, or the retrieval of extinction memories but do not exclude the possibility that the mPFC normally participates in these processes.     

Brief Sensation Seeking Scale for Chinese – Cultural adaptation and psychometric assessment

International behavioral research requires instruments that are not culturally-biased to assess sensation seeking. In this study we described a culturally adapted version of the Brief Sensation Seeking Scale for Chinese (BSSS-C) and its psychometric characteristics. The adapted scale was assessed using an adult sample (n = 238) with diverse educational and residential backgrounds. The BSSS-C (Cronbach alpha = 0.90) was correlated with the original Brief Sensation Seeking Scale (r = 0.85, p < 0.01) and fitted the four-factor model well (CFI = 0.98, SRMR = 0.03). The scale scores significantly predicted intention to and actual engagement in a number of health risk behaviors, including alcohol consumption, cigarette smoking, and sexual risk behaviors. In conclusion, the BSSS-C has adequate reliability and validity, supporting its utility in China and potential in other developing countries.     

Duchenne display responses towards sixteen enjoyable emotions: Individual differences between no and fear of being laughed at

The present study aims to identify whether individuals’ with a fear of being laughed at (gelotophobia), respond with less facially displayed joy (Duchenne display) generally towards enjoyable emotions or only those eliciting laughter. Forty participants (no vs. gelotophobia) described their feelings to scenarios prototypical for the 16 enjoyable emotions proposed by Ekman (Emotions revealed: recognizing faces and feelings to improve communication and emotional life. Times Books, New York, 2003), while being unobtrusively filmed. Facial responses were coded using the Facial Action Coding System (FACS, Ekman et al. in Facial Action Coding System: a technique for the measurement of facial movement. Consulting Psychologists Press, Palo Alto, 2002). The gelotophobes showed less facial expression of joy compared to the non-gelotophobes (Hypothesis 1) and this effect was stronger for frequency and intensity of Duchenne displays towards laughter-eliciting enjoyable emotions than for no laughter-eliciting enjoyable emotions (Hypothesis 2). Moreover, the no gelotophobia group responded more strongly to laughter-eliciting than to no laughter-eliciting enjoyable emotions. Individuals with marked gelotophobia showed the reverse pattern, displaying less joy in laughter-eliciting emotions which may impact on their social interaction, as communication may break down when positive emotion are not reciprocated.     

Multisensory self‐motion encoding in parietal cortex

Navigation through the environment requires the brain to process a number of incoming sensory signals, such as visual optical flow on the retina and motion information originating from the vestibular organs. In addition, tactile as well as auditory signals can help to disambiguate the continuous stream of incoming information and determining the signals resulting from one's own set of motion. In this review I will focus on the cortical processing of motion information in one subregion of the posterior parietal cortex, i.e., the ventral intraparietal area (VIP). I will review (1) electrophysiological data from single cell recordings in the awake macaque showing how self‐motion signals across different sensory modalities are represented within this area and (2) data from fMRI recordings in normal human subjects providing evidence for the existence of a functionally equivalent area of macaque area VIP in the human cortex.