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131.
Family Environments of Women Seeking BRCA1/BRCA2 Genetic Mutation Testing: An Exploratory Analysis 总被引:1,自引:0,他引:1
Keenan LA Lesniak KT Guarnaccia CA Althaus B Ethington G Blum JL 《Journal of genetic counseling》2004,13(2):157-176
Although there is some understanding of the shared characteristics and predictors of psychological distress of women participating in hereditary breast and ovarian cancer registries, these same characteristics are only beginning to be identified in research on community women seeking genetic testing for BRCA1/BRCA2 gene mutations. This study provides an initial exploration of characteristics associated with family environments for 51 community women waiting to receive such genetic testing results. Thirty-four of the 36 women classified on family environment type of the Family Environment Scale (FES) were from Personal Growth-Oriented families. Comparisons of women with and without personal cancer histories resulted in a trend for women with personal cancer histories to be classified as from Independence-Oriented families. Reported distress appears to vary for different family emphases based on family and personal cancer history. A moral-religious family emphasis consistently appeared to be associated with decreased psychological distress. Preliminary analyses comparing these community women (who were not part of a hereditary registry but were self- or physician-referred) seeking genetic testing with normal and distressed family means found that increased cohesion and expressiveness may be related to decreased conflict, indicative of potentially supportive family environments for these women. When compared with normative data, a subset consisting of the Ashkenazi Jewish women showed a trend of less cohesion than normal families, but similar cohesion levels as distressed families. 相似文献
132.
Used linguistic analysis of written narratives of caregivers of hospitalized youth with chronic illness to identify emotional and cognitive processes related to physical and psychological health outcomes following writing. Measures were administered at baseline and 4 months. Experimental group (n = 29) wrote about traumas whereas the control group (n = 24) wrote about summer activities for 20 min on three different days. Compared groups on negative emotion- and cognition-related word use. Tested change in negative emotion- and cognition-related word use as predictors of outcomes in experimental group. Consistent with hypotheses, experimental group used more negative emotion words [F(1, 53) = 77.55, p < .001] and cognition-related words than control group [F(1, 53) = 19.09, p < .001] and an increase in cognition words predicted Physical Health Summary Score on SF-36 (standardized = .37, p < .05). A decrease in negative emotion words was related to Physical Health Summary Score on SF-36 only when entered into regression with change in cognition words (standardized = –.31, p < .05). A decrease in negative emotion together with an increase in cognitive processing facilitated by written emotional disclosure has beneficial effects on physical health-related quality of life. 相似文献
133.
Lawler CP Croen LA Grether JK Van de Water J 《Mental retardation and developmental disabilities research reviews》2004,10(4):292-302
The potential role of environmental factors in autism spectrum disorders (ASD) is an area of emerging interest within the public and scientific communities. The high degree of heritability of ASD suggests that environmental influences are likely to operate through their interaction with genetic susceptibility during vulnerable periods of development. Evaluation of the plausibility of specific neurotoxicants as etiological agents in ASD should be guided by toxicological principles, including dose-effect dependency and pharmacokinetic parameters. Clinical and epidemiological investigations require the use of sufficiently powered study designs with appropriate control groups and unbiased case ascertainment and exposure assessment. Although much of the existing data that have been used to implicate environmental agents in ASD are limited by methodological shortcomings, a number of efforts are underway that will allow more rigorous evaluation of the role of environmental exposures in the etiology and/or phenotypic expression of the disorder. Surveillance systems are now in place that will provide reliable prevalence estimates going forward in time. Anticipated discoveries in genetics, brain pathology, and the molecular/cellular basis of functional impairment in ASD are likely to provide new opportunities to explore environmental aspects of this disorder. 相似文献
134.
This study tested a conceptual model of active coping among a predominantly middle-class sample (N = 92) of Black lesbians (ages 18 to 68) attending a Black lesbian retreat. F. B. Tyler's (1978) active coping dimension of psychosocial competence and L. P. Anderson, C. L. Eaddy, and E. A. Williams's (1990) psychosocial competence model for Black Americans emphasizing the role of individual and environmental factors provided the theoretical framework for the study. A theoretical model was developed to examine whether internal (self-esteem, race and lesbian identification) and external (social support, perceived available lesbian, gay, bisexual, and transgendered resources) factors predicted active coping. Results confirmed that the model of internal and external factors was a statistically significant predictor of active coping. 相似文献
135.
Catalano GD 《Science and engineering ethics》2004,10(2):409-415
A senior level capstone design experience has been developed and offered with a particular emphasis on many of the professional
issues raised in Accreditation Board for Engineering and Technology (ABET) Engineering Criterion IV. The course has sought
to develop student awareness of the ethical foundation of the engineering profession, the global and societal framework within
which engineers practice, and the environmental impact on engineering. The capstone design course also focused upon improving
the technical communications skills of the graduating senior class with both extensive instruction in writing and multiple
workshops dealing with the art of making an effective oral presentation. The effectiveness of the design course was assessed
using Kirkpatrick’s model for evaluating training programs.
An earlier version of this paper was presented at the “Ethics and Social Responsibility in Engineering and Technology” meeting,
New Orleans, 2003. 相似文献
136.
137.
Hale LR Goldstein DS Abramowitz CS Calamari JE Kosson DS 《Behaviour research and therapy》2004,42(6):697-710
Although the hypothesis that psychopathic individuals are characterized by a reduced capacity for experiencing anxiety is central to many theories of psychopathy, most prior studies have examined anxiety and fear measures generally considered outdated in the literature. Moreover, prior findings are mixed, with several studies reporting no relationships between psychopathy and anxiety, and others suggesting negative relationships for the affective, interpersonal aspects of the disorder and positive relationships for the antisocial behavior dimension. To examine whether psychopathy dimensions are associated with contemporary measures of anxiety, the Anxiety Sensitivity Index and State Trait Anxiety Inventory-Trait scale were administered to 157 male inmates. Participants also completed the MMPI-derived Welsh Anxiety Scale (WAS), commonly used in psychopathy studies. Analyses provide no evidence for a negative relationship between psychopathy's affective, interpersonal factor and anxiety sensitivity after controlling for trait anxiety. Trait anxiety and WAS scores were positively associated with the antisocial behavior dimension of psychopathy. Findings do replicate prior relationships between the WAS and psychopathy, suggesting the WAS may measure aspects of negative affectivity that differ from anxiety. 相似文献
138.
139.
Barrett LF Quigley KS Bliss-Moreau E Aronson KR 《Journal of personality and social psychology》2004,87(5):684-697
People differ in the extent to which they emphasize feelings of activation or deactivation in their verbal reports of experienced emotion, termed arousal focus (AF). Two multimethod studies indicate that AF is linked to heightened interoceptive sensitivity (as measured by performance on a heartbeat detection task). People who were more sensitive to their heartbeats emphasized feelings of activation and deactivation when reporting their experiences of emotion over time more than did those who were less sensitive. This relationship was not accounted for by several other variables, including simple language effects. Implications for the role of interoception in experienced emotion and the validity of self-reported emotion are discussed. 相似文献
140.
Are the concepts represented by emotion words different from abstract words in memory? We examined the distinct characteristics of emotion concepts in 3 separate experiments. The first demonstrated that emotion words are better recalled than both concrete and abstract words in a free recall task. In the second experiment, ratings of abstract, concrete, and emotion words were compared on concreteness, imageability, and context availability scales. Results revealed a difference between all 3 word types on each of the 3 scales. The third experiment investigated priming in a lexical decision task for homogeneous (abstract-abstract and emotion-emotion) and heterogeneous (abstract-emotion and emotion-abstract) associated word pairs. Priming occurred only for the homogeneous and heterogeneous abstract-emotion word pair conditions. Possible explanations for these findings are discussed in terms of the circumplex, hierarchical, and semantic activation models. The results are most consistent with the predictions of the semantic activation model. 相似文献