The course of aggression in first-grade children with and without comorbid anxious symptoms

We studied the course of aggressive behavior in an epidemiologically defined sample of first graders with and without comorbid anxious symptoms. Our primary purpose in doing so was to understand whether the stability of aggression in young children was attenuated or strengthened in the presence of comorbid anxiety. Previous studies of older children and adolescents had produced equivocal findings in this regard. Data on anxious symptoms were obtained through an interview of the children, whereas aggressive behavior was assessed through the use of a teacher interview and peer nominations. Assessments were performed in the fall and spring of first grade. In contrast to children classified as aggressive alone in the fall of first grade, boys and girls classified as aggressive and anxious in the fall of first grade were significantly more likely to be classified as aggressive in the spring in terms of teacher ratings and/or peer nominations of aggression. Thus our findings suggest that the link between early and later aggression may be strengthened in the presence of comorbid anxious symptoms, rather than attenuated. Future studies are needed to identify the mechanisms by which the course of aggression is influenced by the presence of comorbid anxiety.The writing of this paper was supported by the following National Institute of Mental Health grants: Epidemiologic Prevention Center for Early Risk Behavior (P50 MH38725); Periodic Outcome of Two Preventive Trials (1RO1 MH42968). The authors would like to thank the Baltimore Public City School System and the children and parents who participated in this study.     

Is cluttering a motor disorder?

A 15-year-old-boy was referred on account of a fluency disorder that was not thought to be stuttering. The problems of the lack of an adequate definition of cluttering are discussed along with the inherent problems of providing a wide-based assessment of this client group. Assessments were conducted on the motoric, linguistic, and intellectual abilities of this client, and the findings are discussed.     

Associations between nonparental care experience and preschooler's emotion regulation in the presence of the mother

This study tested predictions concerning the associations between children's nonparental care experiences and emotion regulation. It involved 53 participants (21 girls and 32 boys) of preschool age and their mothers. The children's care experiences ranged from those who were raised exclusively at home to those who had nonparental care experience beginning in early infancy. The participants were observed in a laboratory playroom, and their mothers were asked to complete questionnaires regarding their children's care histories and their current care situations. The children with extensive nonparental care backgrounds were found to be more likely to use self-directed emotion regulation behaviors when faced with a mildly frustrating situation. In the same situation, the children who had experienced minimal nonparental care were found to be more likely to use other-directed emotion regulation behaviors. Additionally, the children who had experienced care settings with large numbers of children in each care group or who had experienced many caregiver changes were more likely to use self-directed emotion regulation behaviors, whereas those who had experienced settings with smaller care groups and fewer caregiver changes were more likely to use other-directed emotion regulation behaviors.     

On the time course of negative priming: Another look

In two experiments, the pattern of persistence of negative priming effects across delay intervals of 500 and 2,500 msec was assessed using a within-subjects, random sequencing of delays. Neill and Valdes (1992; Neill, Valdes, Terry, & Gorfein, 1992) have argued that a within-subject experimental design is required for decay of negative priming to be seen, in contrast to results reported elsewhere (e.g., Tipper, Weaver, Cameron, Brehaut, & Bastedo, 1991) showing stable negative priming effects across delays. In neither experiment was substantial evidence of decay detected, raising questions for the notion that suppression necessarily declines across brief temporal intervals and for the assertion that episodic retrieval is the sole source of negative priming.     

Pharmacological dissociation of memory: anisomycin, a protein synthesis inhibitor, and leupeptin, a protease inhibitor, block different learning tasks

Inhibition of protein synthesis by anisomycin for a short duration impairs memory of a one-trial inhibitory avoidance task in rats. Memory of escape conditioning involving eight trials is disrupted only if the duration of protein synthesis is prolonged by repeated injections. In marked contrast, olfactory memory of rats trained on two odor discriminations is not affected by anisomycin even if the duration of inhibition is prolonged and the number of trials is reduced to a minimum. In previous work, leupeptin, a thiol proteinase inhibitor, was shown to impair olfactory discrimination learning, but left inhibitory and avoidance conditioning intact. Together, these results provide a pharmacological double dissociation of memory, and suggest that the same chemistries, or mixtures of chemistries, may not be involved in all types of memory.     

Exploration and avoidance in rats with lesions in amygdala and piriform cortex

Lesions localized to specific areas of the amygdala and overlying cortex in rats produced differential effects in several behavioral tasks. Three different types of lesions were tested: central, basolateral, and cortex lateral to the amygdala. Lesions restricted to the central nucleus produced increased activity on all parameters studied in an open-field test, but the other two groups were not changed. In one-way active avoidance all three groups with lesions showed deficits. The most pronounced change was observed in the central group. All groups showed the same degree of retention loss, but in forced extinction of one-way active avoidance after retraining, the cortical and basolateral groups were most defective. A fear-reduction hypothesis is proposed for the central lesion. The basolateral and cortical areas may be more specifically involved in passive avoidance behavior.     

Differential indications for desipramine--results of a controlled multiclinical study]

The antidepressants desipramine and imipramine were compared within the framework of a multiclinical study performed under the conditions of a controlled clinical experiment. There has been found a time-different remission of affective symptoms, which was not detectable for the inhibition of drive. The tachythymoleptic action of desipramine is discussed with reference to these results. Evaluation of the possibility of controlling affects shows different ranges of activity of desipramine and imipramine, with desipramine influencing especially negative psychoenergetic symptoms in the area of drives and emotions and imipramine, restrictive symptoms in addition to differential phenomena of the psychomotor expression.     

Why child neuropsychiatry?]

The author gives a brief survey of the development of Child-Neuropsychiatry in the G.D.R. and subsequently gives reasons for the decision in favor of the unity of neurology and psychiatry as applied to children and juveniles, which is in contrast to developments in other countries. In addition to hygienic, economic, organizational, and medical considerations, this decision was also determined by the fact that a Child-Neuropsychiatrist must, in his practical work as a subspecialist, be able to head a multiprofessional team and, thus, help assure optimum development of a child's personality.