Efficacy of neurostimulation to treat symptoms of Mal de Debarquement Syndrome. A preliminary study using repetitive transcranial magnetic stimulation

Mal de debarquement syndrome (MdDS) is a rare and poorly understood condition of perceived continual motion. Using a multiple‐case design (n = 13; 8 f; 63.5 ± 12.6 years), this study investigated the efficacy of eight 20‐min sessions, over 4 weeks, of repetitive transcranial magnetic stimulation (rTMS) of the dorsolateral pre‐frontal cortex. Compared to sham, rTMS demonstrated improvement in balance and confidence in daily living activities. rTMS shows promise for the treatment of MdDS. However, larger trials with longer intervention periods are required.     

The Depression Anxiety and Stress Scales: Reference data from a large psychiatric outpatient sample

The published norms for the Depression Anxiety and Stress Scale (DASS) give results for clinical populations that largely fall in the severe to very severe categories. As a result, within this population, the ability to compare the comparative contributions of the underlying emotional components is reduced. The present study presents results from a large general psychiatric outpatient population and provides percentile norms with confidence intervals for both the original DASS and the shorter 21‐item form. It is noted that both forms have high validity but that the correlations between scales are higher than those reported in non‐clinical populations. There was little variation between sexes but some variation of results with age with both younger and older cohorts having lower scores except for the Stress scale where there were higher scores in the older group. There is some evidence of a ceiling effect in the Depression and Stress scales. It was noted that nearly a quarter of patient scores fell within the originally defined normal range suggesting that the DASS would not be a particularly sensitive instrument in its previously reported use as a screening instrument for psychiatric illness.     

When do women respond against discrimination? Exploring factors of subtlety,form, and focus

We examined the personal‐group discrimination discrepancy (PGDD), the tendency for women to recognize that others encounter sexism while simultaneously minimizing their own personal experiences with sexism, and the degree to which it (a) applies to all manifestations of discrimination, and (b) extends beyond perceptions of discrimination to taking action against it. Our findings replicated the PGDD when it comes to perceptions of discrimination, but this effect was reversed for behavioral action such that women were more likely to take action against discrimination when it was directed at them personally. We also disentangled the factors of subtlety (subtle vs. overt) and form (formal vs. interpersonal) by showing that women can reliably distinguish between these factors when determining their reactions to discrimination.     

To Dream,Perchance to Think: Discussion of Papers by Noelle Burton and Christopher Bonovitz

This is a discussion of papers by Noelle Burton and Christopher Bonovitz, which explores clinical work with patients who are either developmentally incapable of articulating symbolic thought or immersed in a transference–countertransference position in which abstract thinking is foreclosed.     

Trait anxiety and attenuated negative affect differentiation: a vulnerability factor to consider?

Background and Objectives: Describing emotional experiences using distinct terms, or affect differentiation, has been associated with emotion regulation and adaptive behavior under stress. There is little data, however, examining the association between differentiation and dispositional factors underlying psychopathology. The current study examines the association between differentiation and trait anxiety (TA) given prior evidence of cognitive biases in TA relevant to higher order processing of emotional experiences.

Design: We examined cross-sectionally, via lab-based repeated assessment, the association between differentiation of negative and positive experiences and TA.

Methods: Two hundred twenty-two adults completed an emotion reactivity task including repeated assessments of affect. We hypothesized that individuals higher in trait anxiety (HTA) would have greater difficulty differentiating their experiences.

Results: HTA individuals exhibited lower levels of negative affect (NA) differentiation even when controlling for depression. Although negative emotion intensity was consistently associated with lower differentiation, this did not account for the influence of HTA on differentiation.

Conclusions: These data suggest that HTA individuals have greater difficulty differentiating negative emotions, regardless of negative emotion intensity and depression. As HTA is common to many emotional disorders; this evidence suggests that poor differentiation may also be an important transdiagnostic consideration in models of risk and of affective disease.     

The Genetic Counselor’s Role in Managing Ethical Dilemmas Arising in the Laboratory Setting

Ethical dilemmas are encountered commonly in the setting of the clinical genetic testing laboratory due to the complexity of genetic testing and the number of relevant stakeholders involved in the genetic testing process. Based on their clinical training and role within the laboratory, genetic counselors are uniquely equipped to identify and facilitate management of ethical dilemmas. This paper reviews the historical context of ethical theory and its application to the field of genetic counseling. Theoretical and applied ethics are explored in the context of dilemmas arising in the laboratory setting, with a focus on the role of the laboratory genetic counselor in managing ethical dilemmas. Two illustrative case examples are provided.