Latent Variable Mixture Modeling of Ecological Momentary Assessment Data: Implications for Screening and Adolescent Mood Profiles

Ecological momentary assessment (EMA) studies typically rely on arbitrary decision rules for identifying and excluding invalid responses from the data. In addition, most studies treat independent variables as separate from each other even if their combinations might have importance above the independent contribution of each. Our study aimed to conduct an exploratory latent profile analysis of EMA data to demonstrate an empirical method of identifying invalid responses, and to provide a preliminary investigation of mood profiles. We recruited 20 adolescents between the ages of 13–18 to complete 4 surveys about their internal states each day for 20 days. Participants provided responses on study smartphones using an Android app developed by the study team. Our profile analysis revealed 9 independent profiles. We determined that 3 of these profiles consisted of invalid responses because the integers provided by the participant were nearly invariant. The invalid responses comprised 24.9% of the sample. We also identified 6 valid profiles that were labeled: fatigued (8.7%), good mood/energetic (19.9%), angry/depressed (2.3%), good mood (37.1%), angry (5.7%), and depressed (1.4%). One important implication of the current study is that researchers and clinicians should screen electronic diary data, especially for invariant responding. In addition, it is important for clinicians to note that more than one internal state may drive the mood of an adolescent patient.     

Does a rat release a soaked conspecific due to empathy?

In Experiment 1, rats choosing in an E maze preferred to release a rat standing in a pool of water to dry ground over a rat already standing on dry ground. Five additional experiments showed that the choosing rat’s preference for releasing the wet rat was maintained by two separable outcomes: (1) the social contact offered by the released rat and (2) the reinforcing value of proximity to a pool of water. These results call into question Sato et al.’s (Anim Cogn 18:1039–1047, 2015) claim to have demonstrated that a rat’s releasing of a wet rat to dry ground is empathically motivated.     

Hypothalamic-pituitary-adrenal axis dysregulation and behavioral analysis of mouse mutants with altered glucocorticoid or mineralocorticoid receptor function

Corticosteroid receptors are critical for the maintenance of homeostasis after both psychological and physiological stress. To understand the different roles and interactions of the glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) during stress, it is necessary to dissect the role of corticosteroid signaling at both the system and sub-system level. A variety of GR transgenic mouse lines have recently been used to characterize the role of GR in the CNS as a whole and particularly in the forebrain. We will describe both the behavioral and cellular/molecular implications of disrupting GR function in these animal models and describe the implications of this data for our understanding of normal endocrine function and stress adaptation. MRs in tight epithelia have a long established role in sodium homeostasis. Recently however, evidence has suggested that MRs in the limbic brain also play an important role in psychological stress. Just as with GR, targeted mutations in MR induce a variety of behavioral changes associated with stress adaptation. In this review, we will discuss the implications of this work on MR. Finally, we will discuss the possible interaction between MR and GR and how future work using double mutants (through conventional means or virus based gene alteration) will be needed to more fully understand how signaling through these two steroid receptors provides the adaptive mechanisms to deal with a variety of stressors.     

Short-term clinical risk assessment and management: Comparing the Brockville Risk Checklist and Hamilton Anatomy of Risk Management

The current article aims to examine the performance of two brief, dynamic risk measures – the Brockville Risk Checklist (BRC4) and one of two versions of the Hamilton Anatomy of Risk Management [HARM-FV and electronic HARM-FV (eHARM-FV)] – scored at regular clinical case conferences for forensic psychiatric patients in two different settings. The eHARM represents a first-in-class dynamic risk assessment tool using data analytics. Two studies are presented from two forensic psychiatric hospitals in Ontario, Canada. The first study compared the HARM-FV, scored by trained research staff, with the BRC4, scored concurrently by clinical teams, on 36 forensic inpatients. In the second study, trained research staff scored both the BRC4 and the eHARM-FV on 55 forensic inpatients. Both studies demonstrated that the BRC4 and both HARM-FV tools were moderately and positively correlated with each other, with higher agreement for similar domains and items. In both samples, the risk measures performed better at identifying individuals who engaged in repeated or more serious problematic behavior. The HARM-FV and eHARM-FV produced higher area under the curve values for subsequent behavior compared with the BRC4. All three tools were effective at detecting future aggression and adverse incidents. We did not directly compare the HARM-FV and eHARM-FV.     

Amalgamations of memories: intrusion of information from one event into reports of another

Numerous researchers have reported that exposure to misleading postevent information (MPI) regarding details in a witnessed event can lead people to report false details from the MPI when asked to report the witnessed event. In such studies, the MPI is presented to participants in the context of information about the witnessed event. This experiment tests the hypothesis that postevent exposure to information that participants know is not about the witnessed event can, nonetheless, affect performance on tests of memory for that event. As predicted, when asked to report details of an event depicted in a slide show, participants tended to intrude details mentioned in a recent postevent narrative that described a different event. © 1998 John Wiley & Sons, Ltd.     

Resilience Factors and Suicide Risk for a Sample of Transgender Clients

This study explored how individual- and community-based resilience factors operated together in order to reduce risk of suicide for a sample of transgender therapy clients. We collected cross-sectional survey data from 106 transgender therapy clients at a local community center, including demographic information, experiences of relational support, participants' emotional stability, and risk for suicide. Results from our mediation analysis indicated that high levels of perceived relational support are related to reduced risk for suicide and that this happens by way of a person's emotional stability. Clinical implications for family therapists are discussed based on the significant indirect effect found in this study.     

Functional analysis and operant treatment of food guarding in a pet dog

The present study extended functional analysis (FA) methodology to human-directed resource guarding in a dog in an in-home setting. The subject underwent four conditions including control, attention, escape, and tangible, arranged in a modified FA. The results indicated multiply controlled resource guarding (i.e., escape, attention, and tangible functions). The experimenter then conducted a treatment evaluation involving three function-based treatments in a concurrent multiple baseline design. Resource guarding decreased to zero levels in treatments for each maintaining contingency. Treatment effects were maintained when the subject was tested with an owner, with an untrained handler, a highly preferred treat, in an untrained setting, as well as after 2 weeks in the absence of training. Behavior analytic techniques may hold promise for lasting behavior change for resource guarding in domestic dogs, and should be examined in other populations and with other canine problem behavior.