Alpha3-integrins are required for hippocampal long-term potentiation and working memory

Integrins comprise a large family of heterodimeric, transmembrane cell adhesion receptors that mediate diverse neuronal functions in the developing and adult CNS. Recent pharmacological and genetic studies have suggested that beta1-integrins are critical in synaptic plasticity and memory formation. To further define the role of integrins in these processes, we generated a postnatal forebrain and excitatory neuron-specific knockout of alpha3-integrin, one of several binding partners for beta1 subunit. At hippocampal Schaffer collateral-CA1 synapses, deletion of alpha3-integrin resulted in impaired long-term potentiation (LTP). Basal synaptic transmission and paired-pulse facilitation were normal in the absence of alpha3-integrin. Behavioral studies demonstrated that the mutant mice were selectively defective in a hippocampus-dependent, nonmatch-to-place working memory task, but were normal in other hippocampus-dependent spatial tasks. The impairment in LTP and working memory is similar to that observed in beta1-integrin conditional knockout mice, suggesting that alpha3-integrin is the functional binding partner for beta1 for these processes in the forebrain.     

Attitudes toward computers: a new attitudinal dimension.

The present study examined the reliability and the construct validity of a questionnaire designed to measure the attitudes toward computers in everyday life. A total of 2,050 participants responded to the questionnaire. Confirmatory factor analysis suggests that attitudes toward computers are composed of three dimensions: sense of benefit, sense of dependence, and sense of harm.     

Measuring online learning systems success: applying the updated DeLone and McLean model.

Based on a survey of 232 undergraduate students, this study used the updated DeLone and McLean information systems success model to examine the determinants for successful use of online learning systems (OLS). The results provided an expanded understanding of the factors that measure OLS success. The results also showed that system quality, information quality, and service quality had a significant effect on actual OLS use through user satisfaction and behavioral intention to use OLS.     

On the relation between the acquisition of singular-plural morpho-syntax and the conceptual distinction between one and more than one

We investigated the relationship between the acquisition of singular-plural morpho-syntax and children's representation of the distinction between singular and plural sets. Experiment 1 tested 18-month-olds using the manual-search paradigm and found that, like 14-month-olds (Feigenson & Carey, 2005), they distinguished three objects from one but not four objects from one. Thus, they failed to represent four objects as 'plural' or 'more than one'. Experiment 2 found that children continued to fail at the 1 vs. 4 manual-search task at 20 months of age, even when told, via explicit morpho-syntactic singular-plural cues, that one or many balls are being hidden. However, 22- and 24-month-olds succeeded both with and without verbal cues. Parental report data indicated that most 22- and 24-month-olds, but few 20-month-olds, had begun producing plural nouns in their speech. Also, the success among the older children was due to those children who had reportedly begun producing plural nouns. We discuss a possible role for language acquisition in children's deployment of set-based quantification and the distinction between singular and plural sets.     

工作记忆在数学运算过程中的作用

Baddeley和Hitch(1974)提出的工作记忆模型被广泛地应用数学运算领域,但是已有研究还缺乏系统性。首先,当前的研究主要集中在加法和乘法两种运算上,较少涉及减法、除法和更为抽象的代数运算;第二,研究者对语音环路和中央执行系统的作用进行了较深入的研究,但常常忽略视空间模板的作用;第三,工作记忆在数学运算过程中的作用具有动态性,它受到一些外部因素、数学任务内在因素和个体认知因素（如认知策略）的影响;第四,几乎有关研究都肯定中央执行系统在数学运算过程中的重要作用,然而负荷于中央执行系统的次级任务所含成分或功能的复杂性,导致我们很难确定中央执行系统如何作用于数学运算。对这些问题的研究将是未来可能的研究方向     

运动性心理疲劳问题的研究现状

通过对运动性心理疲劳概念和检测评价方法等问题的国内外研究现状及其局限性和不足进行的综述讨论,作者分析指出目前关于运动性心理疲劳问题的有关研究成果满足不了中国训练体系下训练实践的需要,提出有必要系统进行运动性心理疲劳问题的实证研究。就心理疲劳问题的研究方向和研究切入点,作者认为应综合开展运动性心理疲劳神经生理与心理机制的探索性研究。研究的主要切入点包括：（1）研究建立适合中国运动训练体制与环境的运动性心理疲劳概念,构建运动性心理疲劳概念模型;（2）基于此模型研究建立多维检测评价方法系统和运动性心理疲劳问卷。研究过程中要将神经生理方法与心理测量、行为观察等方法结合起来同步测量,在训练过程中开展纵向追踪与横向调查综合性的实证研究     

叙事语篇中时间表征的评定差异研究

为了探讨时间表征在多大程度上影响人们对叙事属性的判断,让66名博士生被试对12篇删除了明显时间概念词的叙事语篇（创造性与非创造性叙事各6篇）进行时间表征方面的评定,从而检验了“过去”、“现在”、“将来”等时间概念在叙事语篇中的时间表征意义,以及存在的性别、年龄等差异。     

认知失调引起的系列次序错误记忆初探

本实验借鉴认知失调领域自由范式的思路,以系列次序为对象,研究了错误记忆在认知失调影响下的产生特点和机制。结果表明：（1）选择操作对被试的次序回忆产生了显著影响：Z（有选择一无选择）=11．036,p〈0．01;（2）在有选择条件下,接受项目的喜好程度增加（X^2（2）=13．000,P〈0．005）,拒绝项目的喜好程度降低（X^2（2）=9．250．P=0．001）;在无选择的条件下,三种位置的频次分布无显著差异,表明认知失调引发了次序错误记忆;（3）预警变量对于次序回忆的相关程度有显著影响（Z（有提示一无提示）=3．535,P〈0．01）,对于接受项目和拒绝项目的位置回忆无显著影响（接受项目：X^2（2）=0．629,P=0．730;拒绝项目：70（2）=0．180,P=0．914）,表明错误记忆是由认知失调引起,并且难以抑制。     

高校业绩津贴的心理激励模型

本研究探讨了高校业绩津贴发挥激励作用的心理模型。结果表明:收入满意感及工作压力感的交互作用是津贴制发挥激励作用的内在机制;收入满意感及工作压力感通过作用于组织认同对工作业绩有显著的正向预测作用,同时收入激励对工作业绩有直接的正向预测作用。     

和谐二元矩阵模型及其在冲突管理中的应用

和谐是中国文化中的重要因素,本文对和谐的本质从价值性取向和工具性取向进行分析,构建和谐的二元矩阵模型,并将这一模型应用到冲突管理中,提出以和谐为本,建设性解决冲突问题。