What kind of memory supports visual marking?

In visual search tasks, if a set of items is presented for 1 s before another set of new items (containing the target) is added, search can be restricted to the new set. The process that eliminates old items from search is visual marking. This study investigates the kind of memory that distinguishes the old items from the new items during search. Using an accuracy paradigm in which perfect marking results in 100% accuracy and lack of marking results in near chance performance, the authors show that search can be restricted to new items not by visual short-term memory (VSTM) of old locations but by a limited capacity and slow-decaying VSTM of new locations and a high capacity and fast-decaying memory for asynchrony.     

Age differences in the correction processes of context-induced biases: when correction succeeds

Previous research has demonstrated that older adults are more susceptible than young adults to context-induced biases in social judgments. The primary goal of this study was to examine the conditions under which older adults could or could not correct their biases. Young and older adults completed a social judgment task that normally would produce contrast biases in 3 correction cue conditions: no cue, subtle cue, and blatant cue. It was found that both young and older adults corrected their biases in the blatant cue condition, but only young adults corrected in the subtle cue condition. The results suggest that older adults may need more environmental support in correcting their biases.     

Psychosocial factors associated with adolescent boys' reports of dating violence

The prevalence of dating violence, as well as its association with psychosocial factors, was examined among a nationally representative sample of 9th- through 12th-grade U.S. boys (N = 7,434) who completed the 1999 Youth Risk Behavior Survey. The dependent variable was physical dating violence; the independent variables were violence, suicide, substance use, and sexual risk behavior. Unadjusted odds ratios (OR) and 95% confidence intervals (CI) were examined. Multivariate logistic regression was used to examine all significant independent variables from the univariate models. Adjusted OR and 95% CI were examined to assess the significance of these relationships. In terms of prevalence, 9.13% of the boys reported physical dating violence. Boys who reported sad/hopeless feelings (OR = 1.68), had attempted suicide (OR = 2.22), reported fighting (OR = 1.81), had multiple sex partners (OR = 3.53), and reported nonuse of condoms (OR = 1.66) were more likely to report physical dating violence. These findings indicate that physical dating violence among adolescent boys may be a more serious problem than has previously been recognized. It was concluded that intervention programs should include a focus on boys as not only perpetrators but also recipients of dating violence.     

The Meta-Cognitive Beliefs Questionnaire: development of a measure of obsessional beliefs

A 67 item self-report questionnaire called the Meta-Cognitive Beliefs Questionnaire (MCBQ) was developed to assess endorsement of beliefs about the importance of control and negative consequences associated with unwanted, ego-dystonic intrusive thoughts, images and impulses. The MCBQ and a battery of questionnaires that assessed symptoms and cognitions of worry, obsessive-compulsive disorder, anxiety, and depression were administered to large samples of undergraduate students. Beliefs about control of intrusive thoughts and perceived negative consequences due to uncontrolled mental intrusions had a unique significant relationship with obsessions, and to a lesser extent, worry. These findings are consistent with current cognitive behavioral theories that suggest an important role for meta-cognitive beliefs in the pathogenesis of obsessions.     

Effects of experience on fetal voice recognition

Abstract - The ability of human fetuses to recognize their own mother's voice was examined. Sixty term fetuses were assigned to one of two conditions during which they were exposed to a tape recording of their mother or a female stranger reading a passage. Voice stimuli were delivered through a loudspeaker held approximately 10 cm above the maternal abdomen and played at an average of 95 dB SPL. Each condition consisted of three 2-min periods: no stimulus, voice (mother or stranger), and no stimulus. Fetal heart rate increased in response to the mother's voice and decreased in response to the stranger's; both responses were sustained for 4 min. The finding of differential behavior in response to a familiar versus a novel voice provides evidence that experience influences fetal voice processing. It supports an epigenetic model of speech perception, presuming an interaction between genetic expression of neural development and species-specific experience.     

短时作业中警戒绩效影响因素的实验研究:兼用信号检测论分析

本文研究了短时（１小时内）作业中警戒绩效的一些影响因素。实验采用ＥＰ７１０警戒仪,研究了短时作业中时间、信号密度（信噪比）以及信号显著性（占空比）对警戒绩效的影响。使用的方法为信号检测论。因变量指标为辨别力指数ｄ’和判断标准Ｂ。结果发现,作业时间和占空比对警戒绩效没有影响,信噪比对辨别力指数ｄ’有影响但对判断标准Ｂ没有影响。结果提示,在短时作业中,信噪比对警戒绩效起显著作用．     

记忆搜索速度对短时记忆一生发展的影响研究

以横断研究方法探讨一生发展中搜索速度对短时记忆容量的影响。以记忆广度任务和斯腾伯格任务分别测量6~70岁被试短时记忆容量与记忆搜索速度。结果发现:记忆广度在16岁达到最高峰,以后开始下降;一生的不同阶段,斯腾伯格任务中成功搜索的加工过程基本一致,但搜索速度一直在发展;搜索速度可能是贯穿短时记忆发展一生的影响因素。     

Ⅰ期颈椎前后路手术治疗后纵韧带骨化症

为了探讨颈椎前后路手术治疗后纵韧带骨化症的疗效,对65例后纵韧带骨化症患者,Ⅰ期行颈椎前后路手术,采用JOA评分和X线,CT对手术效果进行评价。结果显示,按JOA标准评定,优良率为94％。术后X线及CT均示椎管有效矢状径增加,硬膜囊压迫解除。因此,颈椎前后路手术可以达到减压、稳定的目的,手术效果良好。     

Cocaine-but not methamphetamine-associated memory requires de novo protein synthesis

Context-induced drug craving and continuous drug use manifest the critical roles of specific memory episodes associated with the drug use experiences. Drug-induced conditioned place preference (CPP) in C57BL/6J mouse model, in this regard, is an appropriate behavioral paradigm to study such drug use-associated memories. Requirement of protein synthesis in various forms of long-term memory formation and storage has been phylogenetically demonstrated. This study was undertaken to study the requirement of protein synthesis in the learning and memory aspect of the conditioned place preference induced by cocaine and methamphetamine, two abused drugs of choice in local area. Since pCREB has been documented as a candidate substrate for mediating the drug-induced neuroadaptation, the pCREB level in hippocampus, nucleus accumbens, and prefrontal cortex was examined for its potential participation in the formation of CPP caused by these psychostimulants. We found that cocaine (2.5 and 5.0 mg/kg/dose)-induced CPP was abolished by the pretreatment of anisomycin (50 mg/kg/dose), a protein synthesis inhibitor, whereas methamphetamine (0.5 or 1.0 mg/kg/dose)-induced CPP was not affected by the anisomycin pretreatment. Likewise, cocaine-induced CPP was mitigated by another protein synthesis inhibitor, cycloheximide (15 mg/kg/injection) pretreatment, whereas methamphetamine-induced CPP remained intact by such pretreatment. Moreover, anisomycin treatment 2h after each drug-place pairing disrupted the cocaine-induced CPP, whereas the same treatment did not affect methamphetamine-induced CPP. An increase of accumbal pCREB level was found to associate with the learning phase of cocaine, but not with the learning phase of methamphetamine. We further found that intraaccumbal CREB antisense oligodeoxynucleotide infusion diminished cocaine-induced CPP, whereas did not affect the methamphetamine-induced CPP. Taken together, these data suggest that protein synthesis and accumbal CREB phosphorylation are essential for the learning and consolidation of the cocaine-induced CPP, whereas methamphetamine-induced CPP may be unrelated to the synthesis of new proteins.