音乐训练促进诗句韵律整合加工的神经过程

本研究采用ERP技术, 考察音乐训练组和对照组完成诗句押韵判断任务时, 在绝句末对韵律信息(含声调和韵母两个维度)的整合加工过程。结果发现, 在100~300 ms, 仅音乐训练组在声调/韵母合适条件下, 对韵母/声调的一致性进行深入分析, 并诱发了更大的正波; 在韵母违反条件下, 声调违反相比声调合适诱发了更小的正波。在300~750 ms, 两组被试均在绝句末对诗句内出现的韵母和声调违反进行整合分析并诱发了广泛分布的负波。不过, 对照组仅在声调/韵母合适条件下进行, 而音乐训练组则在声调/韵母违反条件下完成此过程。综上, 音乐训练组和对照组均会在诗句末完成押韵信息的整合加工, 但是音乐训练组对韵律信息(尤其是声调)的加工更敏感和快速, 并且对不同类型的违反有更精细的差异性反应     

时变效应模型及在密集追踪数据分析中的应用

密集追踪数据通常蕴含了心理过程的详细变化信息,反映了某些心理的复杂变化过程。时变效应模型用函数替代恒定的系数,可描述密集追踪数据中随时间推移心理的动态变化过程和时变效应,是分析复杂心理过程的有效方法。在介绍时变效应模型的原理后,通过模拟研究考察模型的表现,结果显示:(1)样本量增加可降低函数估计的误差;(2)惩罚样条法的节点数选择与函数的复杂度有关,函数越复杂,所需节点越多;(3)样本量与节点数对函数估计误差的交互效应不显著。进一步应探讨测量次数、数据分布形态、数据缺失等如何影响模型的表现。     

从海岛抬移看UFO

在一些地方小报上,常有“不明飞行物掠空”和“天外来客访问地球”的披露。由于笔者长期在科技部门工作,脑海中的常识较难对此披露认同,所以一向看此披露后一笑了之。可能是退休后闲来无事,阅读到此类事例较多,同友人交谈时又常接触到“不明飞行物掠空”和“天外来客访问地球”的话题。而且,现在事事讲究国际接轨,对此类事物又有UFO的称呼,由此笔者滋生了对UFO表示点看法的念头。上世纪七十年代笔者在杭州湾搞水文气象工作,那是一个非常平凡日子的下午,笔者正在作水文气象观测。天上云很少,风不大,杭州湾海面波浪较小,但远处海面上有轻雾…     

小学儿童对日常生活事件时间关系推理能力的初探

探查小学儿童对含有“在什么之前”“同时”日常生活事件时间关系的推理发展过程及其影响因素。被试为7岁、9岁、11岁3个年龄组共54名小学儿童,每个年龄组18人。4种问题模式分别为带有传递关系的单模型问题、带有无关前提的单模型问题、含两个前提的单模型问题、有肯定答案的多模型问题。每种问题模式含3种具体探察任务。主要研究结果表明：在本实验条件下,（1）儿童对事件时间顺序关系的推理从7岁到9岁有快速发展的趋势;（2）单模型和多模型任务无显著差异,模型数量似乎不是影响儿童推理成绩的关键因素;（3）儿童能够主动采用5种策略解决问题。逆向关系传递策略是问题解决的有效策略。     

Psychosocial Treatment Strategies in the MTA Study: Rationale, Methods, and Critical Issues in Design and Implementation

The Collaborative Multimodal Treatment Study of Children with Attention Deficit Hyperactivity Disorder (ADHD), the MTA, is the first multisite, cooperative agreement treatment study of children, and the largest psychiatric/psychological treatment trial ever conducted by the National Institute of Mental Health. It examines the effectiveness of Medication vs. Psychosocial treatment vs. their combination for treatment of ADHD and compares these experimental arms to each other and to routine community care. In a parallel group design, 579 (male and female) ADHD children, aged 7–9 years, 11 months, were randomly assigned to one of the four experimental arms, and then received 14 months of prescribed treatment (or community care) with periodic reassessments. After delineating the theoretical and empirical rationales for Psychosocial treatment of ADHD, we describe the MTA's Psychosocial Treatment strategy applied to all children in two of the four experimental arms (Psychosocial treatment alone; Combined treatment). Psychosocial treatment consisted of three major components: a Parent Training component, a two-part School Intervention component, and a child treatment component anchored in an intensive Summer Treatment Program. Components were selected based on evidence of treatment efficacy and because they address comprehensive symptom targets, settings, comorbidities, and functional domains. We delineate key conceptual and logistical issues faced by clinical researchers in design and implementation of Psychosocial research with examples of how these issues were addressed in the MTA study.Deceased     

Family Processes and Treatment Outcome in the MTA: Negative/Ineffective Parenting Practices in Relation to Multimodal Treatment

To elucidate processes underlying therapeutic change in a large-scale randomized clinical trial, we examined whether alterations in self-reported parenting practices were associated with the effects of behavioral, medication, or combination treatments on teacher-reported outcomes (disruptive behavior, social skills, internalizing symptoms) in children with attention-deficit hyperactivity disorder (ADHD). Participants were 579 children with Combined-type ADHD, aged 7–9.9 years, in the Multimodal Treatment Study of Children with ADHD (MTA). We uncovered 2 second-order factors of parenting practices, entitled Positive Involvement and Negative/Ineffective Discipline. Although Positive Involvement was not associated with amelioration of the school-based outcome measures, reductions in Negative/Ineffective Discipline mediated improvement in children's social skills at school. For families showing the greatest reductions in Negative/Ineffective Discipline, effects of combined medication plus behavioral treatment were pronounced in relation to regular community care. Furthermore, only in combination treatment (and not in behavioral treatment alone) was decreased Negative/Ineffective Discipline associated with reduction in children's disruptive behavior at school. Here, children in families receiving combination treatment who showed the greatest reductions in Negative/Ineffective Discipline had teacher-reported disruptive behavior that was essentially normalized. Overall, the success of combination treatment for important school-related outcomes appears related to reductions in negative and ineffective parenting practices at home; we discuss problems in interpreting the temporal sequencing of such process-outcome linkages and the means by which multimodal treatment may be mediated by psychosocial processes related to parenting.     

Parenting and Family Stress Treatment Outcomes in Attention Deficit Hyperactivity Disorder (ADHD): An Empirical Analysis in the MTA Study

Parenting and family stress treatment outcomes in the MTA study were examined. Male and female (579), 7–9-year-old children with combined type Attention Deficit Hyperactivity Disorder (ADHD), were recruited at six sites around the United States and Canada, and randomly assigned to one of four groups: intensive, multi-faceted behavior therapy program alone (Beh); carefully titrated and monitored medication management strategy alone (MedMgt); a well-integrated combination of the two (Comb); or a community comparison group (CC). Treatment occurred over 14 months, and assessments were taken at baseline, 3, 9, and 14 months. Parenting behavior and family stress were assessed using parent-report and child-report inventories. Results showed that Beh alone, MedMgt alone, and Comb produced significantly greater decreases in a parent-rated measure of negative parenting, Negative/Ineffective Discipline, than did standard community treatment. The three MTA treatments did not differ significantly from each other on this domain. No differences were noted among the four groups on positive parenting or on family stress variables. Results are discussed in terms of the theoretical and empirically documented importance of negative parenting in the symptoms, comorbidities and long-term outcomes of ADHD.     

Perceptions of ADHD in China and the United States: a preliminary study

College students (n = 226) and teachers (n = 328) in the United States and China completed a 55-item questionnaire examining perceptions of attention deficit/hyperactivity disorder (ADHD) in the two countries. Although a factor analysis yielded somewhat similar structures for the construct of ADHD, many differences emerged as well, with Chinese participants somewhat more attuned to hyperactivity than inattention. Furthermore, presented with a list of potential perceptions of ADHD, there were significant differences by culture in agreement with most of those statements. Thus, it appears that the concept of ADHD may be similar between the cultures, but the many differences warrant further exploration before ADHD is considered to be equivalent in the two countries.     

Spatial learning in rats is impaired by microinfusions of protein kinase C-gamma antisense oligodeoxynucleotide within the nucleus accumbens

The nucleus accumbens (NAcc) has been shown to play a role in motor and spatial learning. Protein kinase C (PKC) has been implicated in the mechanisms of initiation and maintenance of long-term potentiation that is thought to be involved in the storage of long-term memory. In the present study, the importance of de novo synthesis of PKC-gamma within the NAcc in the acquisition and retention of spatial discrimination learning was assessed using an antisense knockdown approach. Separate groups of Long-Evans rats were exposed to acute microinfusions (6microg/microl) of PKC-gamma antisense oligodeoxynucleotide (AS-ODN), control oligodeoxynucleotide (C-ODN) or vehicle into the NAcc at 24 and 3h before each training session. Behavioral findings showed that the blockade of NAcc-PKC-gamma translation caused impairments in the early phase of learning and retention of spatial information. Biochemical experiments showed that PKC-gamma expression was reduced and Ca(2+)/phospholipid-dependent protein kinase C (PKC) activity was blocked significantly in the AS-ODN-treated rats in comparison with control rats. The present findings suggest that NAcc-PKC-gamma plays a role during the early acquisition of spatial learning. Also, retention test results suggest that NAcc-PKC-gamma may be working as an intermediate factor involved in the onset of molecular mechanisms necessary for spatial memory consolidation within the NAcc.     

小学儿童空间物体位置编码（Ⅰ）

采用找物范式研究小学7、9、11岁儿童利用点与点之间的关系对目标物位置进行编码的认知发展。结果表明：两点距离编码和三点共线编码认知成绩的年龄效应显著,9岁组和11岁组儿童的认知成绩显著好于7岁组儿童的认知成绩。两个不同实验任务对儿童认知成绩的影响不同,7岁组儿童两点距离编码认知成绩显著好于三点共线编码认知成绩,9岁组和11岁组两个任务的认知成绩差异不显著。提供编码线索后,认知成绩有了较大的改善。