Characterization of aggressive behavior and phenytoin response

Recent work has suggested that the success of pharmacological treatment for chronic aggressive behavior may depend, in part, on the subtype of aggressive behavior displayed (e.g. reactive, impulsive aggression vs. predatory, premeditated aggression). The present study examined the usefulness of characterizing aggressive behavior during a 16‐week double‐blind crossover study of phenytoin (PHT) treatment in 41 aggressive adult males. The Impulsive/Premeditated Aggression Scales (IPAS) were used to characterize aggressive behavior as predominantly impulsive or predominantly premeditated in nature. Analyses indicated that participants who did not respond to PHT treatment endorsed significantly more premeditated characteristics on the IPAS than those who responded to PHT treatment. Non‐responders also exhibited fewer aggressive outbursts during placebo treatment, suggesting a greater level of behavior control. Participants who did not complete the study were younger, endorsed significantly more premeditated aggression characteristics and reported more lifetime antisocial behaviors than those who completed the study. Taken together, these data emphasize several factors that may influence the success of pharmacological treatment in aggressive individuals, namely the importance of characterizing the predominant type of problem aggressive behavior. Aggr. Behav. 00:1–6, 2005. © 2005 Wiley‐Liss, Inc.     

A Sequential Analysis of Externalizing in Narrative Therapy with Children

Externalizing, or separating the person from his/her problem-saturated story, is a central approach in narrative therapy. Michael White, one of the therapy’s founders, lately revised his map of the externalizing process in therapy according to Vygotskian theory. In this study we sought to determine whether White’s proposed process was evident in therapy sessions. Sequential analysis indicated that therapists scaffolded children’s responses according to White’s map, and therapists’ and children’s utterances tended to advance across the levels of the map over the course of a session, indicating that White’s model of narrative therapy matched the therapy’s empirical process.     

The Units Of Selection And The Causal Structure Of The World

Genic selectionism holds that all selection can be understood as operating on particular genes. Critics (and conventional biological wisdom) insist that this misrepresents the actual causal structure of selective phenomena at higher levels of biological organization, but cannot convincingly defend this intuition. I argue that the real failing of genic selectionism is pragmatic – it prevents us from adopting the most efficient corpus of causal laws for predicting and intervening in the course of affairs – and I offer a Pragmatic account of causation itself which ultimately bears out the claim that genic selectionism misrepresents the causal structure of selective contexts.     

Factors affecting the social validity of a role-play test of children's social skills

The social validity of a role-play test of children's social skills, the Social Skills Test for Children (SST-C), was evaluated by 63 subjects (33 adults and 30 children) who subjectively judged the quality of three children's role-play performances. The three children were selected as having high, medium, or low social skill based upon their performance on the SST-C. Assessment of the effects of subject characteristics upon judgments of social skill suggested that similarities in age and race between the subjects and the three children tended to diminish perceived differences in social skill among the three children. It was concluded that the social validity of the role-play test was supported only if the persons evaluating social behavior were dissimilar in age and racial characteristics from the persons who were being evaluated.     

Conversation partner mutual adaptation as demonstrated by Fourier series analysis

Persons participating in interview conversations tend to adapt their voice levels, utterance frequency, and pauses with their interaction partners. If individual A participates in dyadic interviews with individuals B, C, D, E, and F, Fourier series analysis of time variant representations of A's utterances tend to be more like those of his dyadic partner than his own utterances in the other conversations. This research points to an objective means where by conversation partners may be identified mechanically without reference to more traditional human understandings of conversation partner identifications.     

Obsessive-compulsive personality disorder and behavioral disinhibition

Although obsessive-compulsive personality disorder (OCPD) is an Axis II diagnosis that is not commonly associated with behavioral disinhibition, the literature contains reports of occasional explosive aggressive outbursts. Existing explanations of OCPD etiology do not address the coexistence of compulsive and impulsive features witnessed in some subpopulations of patients. In this study, the authors present a compensatory theory of OCPD in an effort to explain clinical observations of an unexpectedly large number of OCPD diagnoses among patients clinic referred and self-referred for aggression problems.     

Odor identification impairments in schizophrenia: relationship with demographic measures, clinical variables, and diagnostic subtypes

Smell identification deficits are consistently found in schizophrenia (SZ), but little is known about the nature and characterization of this deficit or its relationship to the phenomenology of the illness. This study aims to further delineate smell identification errors in SZ by examining the relationship of patient demographic differences with smell-identification performance. Our results showed that a patient's gender and education were related to odor-identification scores, with better performance seen in female patients and in those with greater educational attainment. However, there was no effect related to age, ethnicity, or socioeconomic status on odor identification. A smell identification deficit was also unrelated to clinical characteristics of the patients, including age at first hospitalization, number of psychiatric hospitalizations, and duration of illness. Odor identification also did not differ by SZ subtype, nor between SZ and schizoaffective disorder patients. These findings emphasize that odor identification deficits in SZ are unrelated to clinical illness features, cannot be explained by other confounds related to olfaction in the general population, and may be core features related to the SZ disease process.