急性高原病易感人群筛选研究的一些思考

高原缺氧存在易感人群,目前对高原易感人群的筛查主要从进入高原前后人体功能、组织因子及蛋白的变化等方面进行研究,有学者开始从基因水平筛查高原易感人群,基因研究虽然面临许多困难,但它可能是高原易感人群筛查中最有前景的研究方法,应是今后研究的重要方向.     

缺血后适应脑保护的耗散结构基础与脑缺血损伤的非线性特征

脑缺血损伤的机制十分复杂,主要内容涉及谷氨酸兴奋毒性、Ca2＋毒性、自由基损伤、一氧化氮损伤、炎性反应以及内质网和线粒体功能障碍等,这些复杂的机制网络具有耗散结构的非线性特征。近年发现缺血后适应可能通过P13K、Akt、MAPK、PKC等通路,KATP通道,抗凋亡等方式阻止或减轻损伤,从而实现脑保护,而形成一个复杂的信号转导体系。而对复杂的生命系统的研究起着指导作用的耗散结构理论是从更高水平层次研究复杂系统的系统科学,文中将从哲学的角度阐释缺血后适应产生大脑保护的耗散结构基础。     

Internet-delivered physical activity intervention for college students with mental health disorders: a randomized pilot trial

The prevalence of mental health disorders among college students is rising and the increasing rates of anxiety and depression have important societal implications. Physical activity has been proposed as an adjuvant to traditional treatment approaches (i.e. psychotherapy or pharmacotherapy), and the internet is a potentially useful means of delivering physical activity information to the college-aged population. This randomized pilot trial examined the effects of an internet-based physical activity intervention on physical activity, self-efficacy, depression, and anxiety in college students (n?=?47) receiving mental health counseling. Physical activity, depression, anxiety, exercise self-efficacy, and barriers self-efficacy were assessed at baseline and post-intervention. There was a significant time effect for physical activity, with both groups increasing their physical activity levels across the 10-week intervention but with a larger increase in the intervention condition (d?=?0.68) than the control condition (d?=?0.05). Exercise and barriers self-efficacy declined across the intervention, but more so in the control than intervention condition. Effects on depression and anxiety were nonsignificant. Finally, correlation analyses showed increases in physical activity were associated with increases in exercise self-efficacy (r?=?0.62) and barriers self-efficacy (r?=?0.63) and decreases in depression (r?=?-0.44) in the intervention condition, but not in the control condition. These results suggest that an internet-delivered physical activity intervention may be a promising approach to promoting physical activity among college students undergoing mental health counseling.     

Standard back-translation procedures may not capture proper emotion concepts: a case study of Chinese disgust terms

We present data questioning the adequacy of standard back-translation procedures for investigating emotion states across cultures (Brislin, 1970). Our data indicate that the Chinese back-translation of the term disgust has led cross-cultural researchers to accept terms whose themes, goals, and motivations are more akin to the English term anger. Evidence is presented showing that, compared with the standard back-translation method, a more painstaking interview method found a better translational Chinese equivalent for the English term disgust. Implications for the use of back-translation in cross-cultural research are considered.     

Open or close the door to the outgroup? Diversity beliefs moderate the impact of group boundary permeability on attitudes toward the outgroup

The present research investigated the moderating role of diversity beliefs with the aim of reconciling inconsistent findings regarding the impact of group boundary permeability on attitudes toward outgroup. In Study 1, all variables were measured with self‐report scales completed by Chinese participants. In Study 2, diversity beliefs were manipulated by randomly assigning Chinese participants to a high or low diversity belief condition. In Study 3, we replicated the moderating model with American participants. Results of all three studies indicated that diversity beliefs moderated the relationship between group boundary permeability and attitudes toward outgroup. Individuals with high diversity beliefs held more positive attitudes toward the outgroup when the group boundary was permeable (vs. impermeable). Conversely, individuals with low diversity beliefs held more negative attitudes toward the outgroup when the group boundary was permeable (vs. impermeable). These findings suggest that when the inflow of the outgroup members is inevitable, attitudes toward the outgroup may be effectively improved by increasing diversity beliefs.     

Counselor Supervision: A Comparison Across States and Jurisdictions

Counselor licensure portability models have focused primarily on academic training with only little discussion concerning postgraduate supervision. Using a qualitative content analysis, the authors analyzed the supervision rules and laws in all 53 licensing jurisdictions. The results of this study reflect the lack of a consistent set of supervision guidelines across all 53 jurisdictions. Further study and reflection on these results could lead to the development of a supervision model for postgraduate supervision.     

积极的情绪能否促进多媒体学习?基于元分析的视角

在多媒体学习中,越来越多的研究者开始探究通过教学设计诱发的积极情绪能否达到增进教学效果、促进学习的目的。但诱发的积极情绪究竟能否影响学习者的学习效果和主观感受,以往实证研究的结果仍存在争议。本研究采用元分析技术,探讨多媒体学习背景下诱发的情绪对学习者学习效果和主观感受的影响。研究共纳入文献21篇,在积极情绪、保持成绩、迁移成绩上分别生成了24个（2454人）、28个（2658人）和27个（2447人）独立效应量。结果发现：相对中性情绪组,积极情绪组的确表现出更高的积极情绪（d=0.64）,学习者的保持成绩（d=0.25）、迁移成绩（d=0.30）、心理努力（d=0.21）和学习满意度（d=0.42）也更高;诱发的情绪对多媒体学习的影响效果在一定程度上受积极情绪诱导方式、外诱材料类型、呈现步调、学习材料时长的调节。     

汉字字组时间顺序的内隐记忆研究

采用再认与偏好测验的内隐记忆方法,以文字相同而字序不同的三类汉字字组为刺激材料,对汉字字组进行启动效应的实验研究,探讨汉字字组内隐的时间顺序表征存在的可能性及其加工特点。结果表明：汉字字组中字与字之间存在内隐的时间顺序表征,这种内隐的时间顺序表征是对刺激项目知觉特征中时间维度的一种反映,受知觉表征系统支配,具有自动加工和提取的特点。     

条件性恐惧泛化的性别差异

恐惧的过度泛化是焦虑障碍的核心症状之一, 表现为患者对与原危险刺激极不相似的中性刺激也有着较高强度的恐惧反应。临床上, 女性比男性更有可能患焦虑障碍, 因而对恐惧泛化进行性别差异研究可以为解释女性有着更高焦虑障碍发病率提供新的角度, 同时为临床治疗提供参考。本研究采用辨别性条件恐惧范式, 以主观预期值和皮电反应值作为测量指标, 从行为和生理两个层面对条件性恐惧泛化程度和恐惧泛化消退的性别差异进行研究。结果发现, 在恐惧泛化程度上, 未出现显著性别差异。在恐惧泛化消退上, 在主观预期值和皮电反应值两个层面均有着显著性别差异, 具体表现为相较于男性, 女性恐惧泛化的消退更慢, 持续时间更长。研究结果表明, 女性焦虑障碍高发病率的潜在影响因素之一可能在于女性对于恐惧泛化刺激的难以消除。     

Positional character frequency and word spacing facilitate the acquisition of novel words during Chinese children's reading

Children's eye movements were recorded to examine the role of word spacing and positional character frequency on the process of Chinese lexical acquisition during reading. Three types of two-character novel pseudowords were constructed: words containing characters in positions in which they frequently occurred (congruent), words containing characters in positions they do not frequently occur in (incongruent) and words containing characters that do not have a strong position bias (balanced). There were two phases within the experiment, a learning phase and a test phase. There were also two learning groups: half the children read sentences in a word-spaced format and the other half read the sentences in an unspaced format during the learning phase. All the participants read normal, unspaced text at test. A benefit of word spacing was observed in the learning phase, but not at test. Also, facilitatory effects of positional character congruency were found both in the learning and test phase; however, this benefit was greatly reduced at test. Furthermore, we did not find any interaction between word spacing and positional character frequencies, indicating that these two types of cues affect lexical acquisition independently. With respect to theoretical accounts of lexical acquisition, we argue that word spacing might facilitate the very earliest stages of word learning by clearly demarking word boundary locations. In contrast, we argue that characters' positional frequencies might affect relatively later stages of word learning.