组织微阵列方法检测CD105、VEGF-C在肝癌组织中的表达

新生血管生成不仅为肿瘤组织提供营养支持,而且是肿瘤细胞进入循环系统的途径.CD105仅在激活的上皮细胞表达;VEGF-C为重要的血管生成因子之一,但二者与肝癌转移是否存在关联尚不明晰.探讨CD105及VEGF-C表达与肝癌肝内转移的关联.构建承载37例肝癌及癌旁组织的组织微阵列,免疫组织化学方法检测CD105及VEGF-C的表达.存在肝内转移的肝癌组织MVD-CD105均值为28.4±19.4,而无肝内转移的肝癌组织MVD-CD105均值为5.4±5.2,差异显著(P＜0.01);VEGF-C在存在肝内转移的肝癌组织表达率为46.15%(6/14),无肝内转移的肝癌组织中表达率为41.67%(10/24),二者无显著差异.MVD-CD105分值与肝癌肝内转移密切相关;血管生成可能在肝癌肝内转移过程中起重要作用.     

Alliance-Outcome Associations in a Community-Based Social Skills Intervention for Youth With Autism Spectrum Disorder

Although the alliance is a consistent predictor of treatment outcomes in psychosocial interventions, few studies have examined this association among youth with autism spectrum disorder (ASD). In particular, youth-therapist alliance has never been examined in social skills interventions (SSIs), a common modality for this population. In this study, thirty-four youth with ASD (M_age = 12.41; 79% male) participated in a community-delivered, group-based SSI in a summer camp format led by eight Head Therapists (M_age = 32.12; 50% male). Early alliance and change in alliance over the course of the treatment were assessed via self- and observer-reported measures. Both self- and observer-rated alliance were associated with positive treatment outcomes as reported by parents (decreased problem behaviors) and other peers in the group (reciprocated friendship and social preference). These results provide the first evidence of the role of the alliance in an SSI for youth with ASD and add to the growing body of literature that demonstrates the importance of assessing and addressing the alliance in treatment for this population.     

Comparing Chinese youth with American youth on adjustment: An illustration of measurement issues in cross-cultural research

In this article, we used results from two studies to show the need to go beyond linguistic equivalence to establish construct validity and measurement invariance in cross-cultural research. Study 1 examined Rosenberg Self-Esteem (RSE; 10 items) data from 156 Mainland Chinese youth (M = 13.8 years, SD = .53) and 213 Chinese-American youth (M = 13.6 years, SD = 2.1) from high socioeconomic status (SES) families. The Chinese translation of the RSE has been widely used. Study 2 included 1060 Mainland Chinese youth (M = 15.6 years, SD = 2.3) and 412 racially diverse American youth (M = 16.0, SD = 2.9) from all SES backgrounds. Data were collected with the third and newest edition of the Behavioural Assessment System for Children-Self Report of Personality (BASC-3-SRP; 189 items). We translated and back-translated the BASC-3-SRP between English and Chinese to establish linguistic equivalence. All participants were females. Study 1 showed that the RSE had acceptable internal consistency but lacked construct validity. Study 2 showed that the original and the translated BASC-3-SRP had good internal consistency and construct validity, but nine of its 16 subscales lacked measurement invariance. These results highlight measurement issues facing international and cross-cultural research.     

From Implicit Theories to Creative Achievements: The Mediating Role of Creativity Motivation in the Relationship between Stereotypes,Growth Mindset,and Creative Achievement

Research has demonstrated that implicit theories of creativity are crucial in shaping an individual’s behavior and real‐life decisions toward being creative. The present study proposed and examined the underlying mechanisms of how two kinds of implicit theories—the growth mindset of the creative self and the stereotype of creative others—are associated with creative achievements through the mediating role of creativity motivation. Participants were 606 undergraduate students who were enrolled in an education major in two universities in China. Overall, the study found that Chinese students held a positive image toward a creative student, regarding him or her as highly competent, warm, and popular. Student perceptions of a creative other were positively related to their growth mindset of creativity. Moreover, results verified both the mediating role of creativity motivation on growth mindset, as well as the effect of positive stereotyping of the creative other on students’ creative achievement. These findings point to promising creativity motivation strategies including the cultivation of a malleable view of creativity and of creative role models, that may, in turn, promote creative achievement by encouraging students to do, learn, and accomplish new things.     

被动性社交网站使用与青少年体像烦恼的关系:体像比较和体像自我差异的中介作用

为探讨被动性社交网站使用和青少年体像烦恼的关系,基于社会比较理论和自我差异理论,采用被动性社交网站使用问卷、社交网站体像比较量表、理想体像问卷和体像烦恼量表,对789名初、高中生进行调查。结果表明：（1）被动性社交网站使用对青少年体像烦恼具有显著的正向预测作用;（2）体像比较和体像自我差异能在被动性社交网站使用和体像烦恼的关系中起中介作用;（3）在被动性社交网站使用与体像烦恼的关系中,女生的体像比较和体像自我差异起并行中介作用,而对男生而言,体像比较和体像自我差异起链式中介作用。研究结果表明被动性社交网站使用不仅能直接影响青少年的体像烦恼,还可通过体像比较和体像自我差异的间接作用对青少年体像烦恼产生影响,且中介路径存在性别差异。     

基本需要在导师排斥感知与研究生心理健康的关系中的作用

为探讨导师排斥感知对研究生心理健康的影响及作用机制,本研究采用导师排斥感知问卷、基本需要问卷、生活满意度量表、简版流调中心抑郁量表及攻击问卷,对北京市六所本科院校的864名在校硕士和博士研究生进行问卷调查。结果发现：（1）导师排斥感知正向预测研究生的抑郁和攻击性,负向预测其生活满意度;（2）基本需要在导师排斥感知与研究生的生活满意度、抑郁之间起着完全中介作用,在导师排斥感知与攻击性之间起部分中介作用。结果表明,研究生导师排斥感知越强,基本需要的满足水平越低,进而导致研究生的抑郁水平越高、攻击性越强、生活满意度越低。即研究生感知的导师排斥感越强,其心理健康水平越低。