Dopamine D1 receptors are responsible for stress-induced emotional memory deficit in mice

It is established that stress impairs spatial learning and memory via the hypothalamus-pituitary-adrenal axis response. Dopamine D1 receptors were also shown to be responsible for a stress-induced deficit of working memory. However, whether stress affects the subsequent emotional learning and memory is not elucidated yet. Here, we employed the well-established one-trial step-through task to study the effect of an acute psychological stress (induced by tail hanging for 5, 10, or 20?min) on emotional learning and memory, and the possible mechanisms as well. We demonstrated that tail hanging induced an obvious stress response. Either an acute tail-hanging stress or a single dose of intraperitoneally injected dopamine D1 receptor antagonist (SCH23390) significantly decreased the step-through latency in the one-trial step-through task. However, SCH23390 prevented the acute tail-hanging stress-induced decrease in the step-through latency. In addition, the effects of tail-hanging stress and/or SCH23390 on the changes in step-through latency were not through non-memory factors such as nociceptive perception and motor function. Our data indicate that the hyperactivation of dopamine D1 receptors mediated the stress-induced deficit of emotional learning and memory. This study may have clinical significance given that psychological stress is considered to play a role in susceptibility to some mental diseases such as depression and post-traumatic stress disorder.     

An index of prenatal steroid exposure predicts adult face perception skills

Face perception skills are fundamental to social cognition, yet they vary markedly across individuals. This diversity has stimulated controversy over the relative contributions of genetic factors, prenatal environment, and postnatal experience to face perception. Recent twin studies have found that face perception is heritable, highlighting the potential for substantial prenatal determination of these skills. In contrast, previous work on potential influences of the prenatal hormonal environment on social cognition have found no association between 2D:4D, a marker for prenatal androgen exposure, and processing of facial emotional expressions, apparently precluding a major role for prenatal hormones in governing face perception. We propose that substantial predictive relationships between 2D:4D and face perception may have been masked in previous work because the task employed required both face perception and processing of others?? emotions, the latter component being greatly influenced by circulating hormones in adults. To assess prenatal hormone influences on face perception without requiring emotion processing, we related 2D:4D to the face inversion effect (FIE), a measure of the recruitment of specialist face processes to visual perception. The magnitude of the resulting predictive relationship (r = .52) compared surprisingly well with that found between identical twins?? face perception (rs = .27?C.61), suggesting that mechanisms of 2D:4D may account for a substantial proportion of perinatal influences on face processing. Furthermore, we employed 2D:4D as a common scale to map individual differences in the FIE onto prenatal testosterone:estrogen ratios, assayed by Lutchmaya, Baron-Cohen, Raggatt, Knickmeyer, and Manning (Early Human Development 77:23?C28, 2004). The substantial overlap between the two data sets further implicates prenatal steroids in adult face perception skills.     

The AB Identification Survey: Identifying Absolute versus Relative Determinants of Happiness

This article introduces a simple survey method to distinguish between two types of variables that affect happiness—type A, which exerts an absolute effect on happiness, and type B, which affects happiness only through social context. The authors validate the method by comparing its findings with the findings of a theoretically superior but less practical experimental method, and use the method to identify the AB nature of a variety of naturally-occurring variables among both college students and people with work experience. We conclude by discussing the limitation of this method as well as its potential to inform policymakers about where to invest resources in order to improve people’s happiness over time.     

Distinct processing for pictures of animals and objects: evidence from eye movements

Many studies have suggested that emotional stimuli orient and engage attention. There is also evidence that animate stimuli, such as those from humans and animals, cause attentional bias. However, categorical and emotional factors are usually mixed, and it is unclear to what extent human context influences attentional allocation. To address this issue, we tracked participants' eye movements while they viewed pictures with animals and inanimate images (i.e., category) as focal objects. These pictures had either negative or neutral emotional valence, and either human body parts or nonhuman parts were near the focal objects (i.e., context). The picture's valence, arousal, position, size, and most of the low-level visual features were matched across categories. The results showed that nonhuman animals were more likely to be attended to and to be attended to for longer times than inanimate objects. The same pattern held for the human contexts (vs. nonhuman contexts). The effects of emotional valence, category, and context interacted. Specifically, in images with a negative valence, focal animals and objects with human context had comparable numbers of gaze fixations and gaze duration. These results highlighted the attentional bias to animate parts of a picture and clarified that the effects of category, valence, and picture context interacted to influence attentional allocation.     

The prevalence of loneliness among adults: a case study of the United Kingdom

Within contemporary Western (post) modern societies, loneliness is seen as a problem that is particularly associated with old age. Much less attention has been given to examining variations in loneliness across age groups. We examine patterns of loneliness across adults aged 15 years and older in the United Kingdom using data from the European Social Survey. We first consider the prevalence of loneliness among the adult population; then the relationship between loneliness and a range of key risk factors, and finally the relationship with age for each of our risk factors. Loneliness demonstrates a nonlinear U-shaped distribution, with those aged under 25 years and those aged over 65 years demonstrating the highest levels of loneliness. Depression is associated with loneliness for all age groups. Poor physical health is associated with loneliness in young adult and midlife but not later life. For those in mid and later life, the quality of social engagement is protective against loneliness, while for young adults it is the quantity of social engagement. This indicates that different factors may endow vulnerability (or protect) against loneliness at different stages of life and suggests that preventative strategies or interventions that reflect these variations need to be developed.     

Non-target language processing in Chinese-English bilinguals: a study of event-related potential

The event-related brain potential (ERP) technique was used to investigate the neural mechanism of non-target language processing in Chinese-English bilinguals. Participants were presented with a mixed list of Chinese and English words and required to make conceptual decisions for words in one language and ignore words in the other non-target language. Regardless of whether the nontarget word was in Chinese or English, the ERPs they elicited were modulated by word frequency, suggesting that their meaning had been accessed. The N400 peak was delayed in the English as the non-target language condition, probably because participants were less proficient in English. The results suggest that the non-target language can be processed during conceptual tasks with participants' proficiency in this language being a critical factor.     

Exploratory and confirmatory factor analysis of a short-form of the EMBU among Chinese adolescents

The present study used a sample of Chinese adolescents and validated a short-form of the Egna Minnen Betr?ffande Uppfostran: One's Memories of Upbringing (s-EMBU) assessing perceived parental rearing styles. A Chinese revision of the s-EMBU by the authors was administered to a total of 779 high school students, ages 11 to 19 years. Exploratory factor analysis with half of the sample yielded a three-factor solution of Rejection, Emotional Warmth, and Overprotection, accounting for 47.1% of the total variance onthe father form and 48.8% of the total variance on the mother form. Then, confirmatory factor analysis indicated a good fit of the three-factor model to the data in the other half of the sample. The three subscales consisted of 6, 6, and 7 items, respectively. Scores on these subscales had Cronbach alphas ranging from .71 to .81, indicating adequate internal consistency. These psychometric properties suggest its applicability for research with Chinese adolescents.     

Social Construction and its Development: Liping Yang Interviews Kenneth Gergen

Nanjing University psychologist Liping Yang interviews Kenneth Gergen on the development of social constructionist thought and practice. The conversation treats a variety of issues, including the development of constructionism as a new paradigm, qualitative research, education and other practices informed by constructionism, value loaded science, relativism, and the Taos Institute.