组织微阵列方法检测CD105、VEGF-C在肝癌组织中的表达

新生血管生成不仅为肿瘤组织提供营养支持,而且是肿瘤细胞进入循环系统的途径.CD105仅在激活的上皮细胞表达;VEGF-C为重要的血管生成因子之一,但二者与肝癌转移是否存在关联尚不明晰.探讨CD105及VEGF-C表达与肝癌肝内转移的关联.构建承载37例肝癌及癌旁组织的组织微阵列,免疫组织化学方法检测CD105及VEGF-C的表达.存在肝内转移的肝癌组织MVD-CD105均值为28.4±19.4,而无肝内转移的肝癌组织MVD-CD105均值为5.4±5.2,差异显著(P＜0.01);VEGF-C在存在肝内转移的肝癌组织表达率为46.15%(6/14),无肝内转移的肝癌组织中表达率为41.67%(10/24),二者无显著差异.MVD-CD105分值与肝癌肝内转移密切相关;血管生成可能在肝癌肝内转移过程中起重要作用.     

Comparing Chinese youth with American youth on adjustment: An illustration of measurement issues in cross-cultural research

In this article, we used results from two studies to show the need to go beyond linguistic equivalence to establish construct validity and measurement invariance in cross-cultural research. Study 1 examined Rosenberg Self-Esteem (RSE; 10 items) data from 156 Mainland Chinese youth (M = 13.8 years, SD = .53) and 213 Chinese-American youth (M = 13.6 years, SD = 2.1) from high socioeconomic status (SES) families. The Chinese translation of the RSE has been widely used. Study 2 included 1060 Mainland Chinese youth (M = 15.6 years, SD = 2.3) and 412 racially diverse American youth (M = 16.0, SD = 2.9) from all SES backgrounds. Data were collected with the third and newest edition of the Behavioural Assessment System for Children-Self Report of Personality (BASC-3-SRP; 189 items). We translated and back-translated the BASC-3-SRP between English and Chinese to establish linguistic equivalence. All participants were females. Study 1 showed that the RSE had acceptable internal consistency but lacked construct validity. Study 2 showed that the original and the translated BASC-3-SRP had good internal consistency and construct validity, but nine of its 16 subscales lacked measurement invariance. These results highlight measurement issues facing international and cross-cultural research.     

From Implicit Theories to Creative Achievements: The Mediating Role of Creativity Motivation in the Relationship between Stereotypes,Growth Mindset,and Creative Achievement

Research has demonstrated that implicit theories of creativity are crucial in shaping an individual’s behavior and real‐life decisions toward being creative. The present study proposed and examined the underlying mechanisms of how two kinds of implicit theories—the growth mindset of the creative self and the stereotype of creative others—are associated with creative achievements through the mediating role of creativity motivation. Participants were 606 undergraduate students who were enrolled in an education major in two universities in China. Overall, the study found that Chinese students held a positive image toward a creative student, regarding him or her as highly competent, warm, and popular. Student perceptions of a creative other were positively related to their growth mindset of creativity. Moreover, results verified both the mediating role of creativity motivation on growth mindset, as well as the effect of positive stereotyping of the creative other on students’ creative achievement. These findings point to promising creativity motivation strategies including the cultivation of a malleable view of creativity and of creative role models, that may, in turn, promote creative achievement by encouraging students to do, learn, and accomplish new things.     

汉语发展性阅读障碍儿童视觉同时性加工技能子成分的发展及其与阅读的关系

通过分别以高频汉字(实验1)和图形非言语材料(实验2)为刺激的两个联合视觉注意任务, 并采用基于Budensen视觉注意理论的参数估计方法, 系统地探查小学三~六年级汉语发展性阅读障碍儿童的视觉同时性加工技能缺陷的内在机制。以43名汉语发展性阅读障碍儿童和46名生理年龄匹配典型发展儿童为被试, 每类被试均被分为小学中年级组(三、四年级)和高年级组(五、六年级)。两个实验均发现不同年级组的阅读障碍儿童在知觉加工速度参数上显著小于控制组儿童。在空间注意分布权重参数上, 实验1的结果显示, 不同于控制组儿童向左侧化发展的注意分布模式, 两个年级组的阅读障碍儿童均表现为无偏的注意分布; 而实验2未发现显著组别差异。且这两种同时性加工子技能分别与不同水平的汉语阅读技能密切相关。结果表明, 汉语阅读障碍儿童在同时加工多个视觉刺激时存在持续的知觉加工速度缓慢的问题, 在同时加工言语类刺激时还表现出异常的空间注意分布模式。本研究有助于从基础认知层面揭示汉语发展性阅读障碍儿童的缺陷机理, 为进一步设计相关的提高阅读效率的干预方案提供理论依据。     

被动性社交网站使用与青少年体像烦恼的关系:体像比较和体像自我差异的中介作用

为探讨被动性社交网站使用和青少年体像烦恼的关系,基于社会比较理论和自我差异理论,采用被动性社交网站使用问卷、社交网站体像比较量表、理想体像问卷和体像烦恼量表,对789名初、高中生进行调查。结果表明：（1）被动性社交网站使用对青少年体像烦恼具有显著的正向预测作用;（2）体像比较和体像自我差异能在被动性社交网站使用和体像烦恼的关系中起中介作用;（3）在被动性社交网站使用与体像烦恼的关系中,女生的体像比较和体像自我差异起并行中介作用,而对男生而言,体像比较和体像自我差异起链式中介作用。研究结果表明被动性社交网站使用不仅能直接影响青少年的体像烦恼,还可通过体像比较和体像自我差异的间接作用对青少年体像烦恼产生影响,且中介路径存在性别差异。     

基本需要在导师排斥感知与研究生心理健康的关系中的作用

为探讨导师排斥感知对研究生心理健康的影响及作用机制,本研究采用导师排斥感知问卷、基本需要问卷、生活满意度量表、简版流调中心抑郁量表及攻击问卷,对北京市六所本科院校的864名在校硕士和博士研究生进行问卷调查。结果发现：（1）导师排斥感知正向预测研究生的抑郁和攻击性,负向预测其生活满意度;（2）基本需要在导师排斥感知与研究生的生活满意度、抑郁之间起着完全中介作用,在导师排斥感知与攻击性之间起部分中介作用。结果表明,研究生导师排斥感知越强,基本需要的满足水平越低,进而导致研究生的抑郁水平越高、攻击性越强、生活满意度越低。即研究生感知的导师排斥感越强,其心理健康水平越低。     

Achieving Effective Remote Working During the COVID-19 Pandemic: A Work Design Perspective

Existing knowledge on remote working can be questioned in an extraordinary pandemic context. We conducted a mixed-methods investigation to explore the challenges experienced by remote workers at this time, as well as what virtual work characteristics and individual differences affect these challenges. In Study 1, from semi-structured interviews with Chinese employees working from home in the early days of the pandemic, we identified four key remote work challenges (work-home interference, ineffective communication, procrastination, and loneliness), as well as four virtual work characteristics that affected the experience of these challenges (social support, job autonomy, monitoring, and workload) and one key individual difference factor (workers’ self-discipline). In Study 2, using survey data from 522 employees working at home during the pandemic, we found that virtual work characteristics linked to worker's performance and well-being via the experienced challenges. Specifically, social support was positively correlated with lower levels of all remote working challenges; job autonomy negatively related to loneliness; workload and monitoring both linked to higher work-home interference; and workload additionally linked to lower procrastination. Self-discipline was a significant moderator of several of these relationships. We discuss the implications of our research for the pandemic and beyond.     

Word Order Variation is Partially Constrained by Syntactic Complexity

Previous work suggests that when speakers linearize syntactic structures, they place longer and more complex dependents further away from the head word to which they belong than shorter and simpler dependents, and that they do so with increasing rigidity the longer expressions get, for example, longer objects tend to be placed further away from their verb, and with less variation. Current theories of sentence processing furthermore make competing predictions on whether longer expressions are preferentially placed as early or as late as possible. Here we test these predictions using hierarchical distributional regression models that allow estimates of word order and word order variation at the level of individual dependencies in corpora from 71 languages, while controlling for confounding effects from the type of dependency (e.g., subject vs. object), and the type of clause (main vs. subordinate) involved as well as from trends that are characteristic of individual languages, language families, and language contact areas. Our results show the expected correlations of length with position and variation only for two out of six dependency types (obliques and nominal modifiers) and no difference between clause types. These findings challenge received theories of across-the-board effects of complexity on word order and word order variation and call for theoretical models that relativize effects to specific kinds of syntactic structures and dependencies.     

中国人社会善念的心理结构

为探究中国人社会善念的心理结构, 研究采用人格词汇法, 在开放调查收集的词汇中选取代表社会善念的心理词语, 确立了社会善念词库。通过两次探索性因素分析和验证性因素分析, 得到包含18个人格特质词的社会善念词汇评定量表和包含17项描述的社会善念自陈量表。研究表明, 中国人的社会善念是一种具有二阶四因素结构的人际特质, 二阶是指宜人特质和外倾特质, 四因素分别是善良尊重、谦和恭逊、包容理解和积极开放。