A Review on Spinal Muscular Atrophy: Awareness,Knowledge, and Attitudes

Spinal Muscular Atrophy (SMA) is one of the most common genetic causes of infant death. There is presently no cure, but the therapeutic pipeline is promising. Given the prevalence of SMA coupled with the potential for new treatment options, universal carrier screening, and newborn screening, we conducted a literature review of the awareness, knowledge, and attitudes held by the public and non-geneticist clinicians about various aspects of SMA. We then identify recommendations for targeting additional research, training, and educational efforts to increase awareness. In the limited available literature, we found that the public is generally unfamiliar with SMA but has favorable views of carrier and newborn screening. Clinicians also had limited understanding of SMA. Further research into knowledge and attitudes of healthcare providers and the general public will help develop a better understanding of education gaps and inform outreach efforts. These educational efforts are needed to complement the momentum as treatments are being developed and tested. Furthermore, professional societies are proposing routine carrier screening and SMA may achieve newborn screening status, which will change the SMA landscape for genetics professionals and families. Thus, it is important to explore knowledge and attitudes about SMA to allow us to prepare for when SMA attains higher public and clinician recognition.     

A Big Five approach to self-regulation: personality traits and health trajectories in the Hawaii longitudinal study of personality and health

Self-regulatory processes influencing health outcomes may have their origins in childhood personality traits. The Big Five approach to personality was used here to investigate the associations between childhood traits, trait-related regulatory processes and changes in health across middle age. Participants (N = 1176) were members of the Hawaii longitudinal study of personality and health. Teacher assessments of the participants’ traits when they were in elementary school were related to trajectories of self-rated health measured on 6 occasions over 14 years in middle age. Five trajectories of self-rated health were identified by latent class growth analysis: Stable Excellent, Stable Very Good, Good, Decreasing and Poor. Childhood Conscientiousness was the only childhood trait to predict membership in the Decreasing class vs. the combined healthy classes (Stable Excellent, Stable Very Good and Good), even after controlling for adult Conscientiousness and the other adult Big Five traits. The Decreasing class had poorer objectively assessed clinical health measured on one occasion in middle age, was less well-educated, and had a history of more lifespan health-damaging behaviors compared to the combined healthy classes. These findings suggest that higher levels of childhood Conscientiousness (i.e. greater self-discipline and goal-directedness) may prevent subsequent health decline decades later through self-regulatory processes involving the acquisition of lifelong healthful behavior patterns and higher educational attainment.     

Using Tablets to Collect Data From Young Children

Mobile, touch-screen devices are increasingly ubiquitous in children’s lives. The extensive use of such devices presents an exciting opportunity for data collection. We describe a simple method for creating cross-platform, interactive tablet experiments using open Web-based resources. We illustrate this method by collecting data from 1- to 4-year-old children in a word-recognition paradigm, using 3 different techniques: tablets, eye tracking, and an in-person storybook paradigm. Both accuracy and reaction-time data from the tablet compared favorably with the other methods. Tablets should be considered as a viable method for collecting low-cost, well-controlled developmental data.     

Sensation seeking, impulsive decision-making, and risky sex: implications for risk-taking and design of interventions

In an HIV prevention study, 2949 ninth-grade students in 17 high schools in two Midwestern U.S. cities were administered scales measuring sensation seeking and impulsive decision-making and their separate and combined relationships to a number of indicators of sexual risk-taking. Measures of sexual risk-taking included intentions to have sex, ever had sex, number of lifetime sexual partners, been pregnant or caused a pregnancy, used a condom, used marijuana, had unwanted sex when drunk, had unwanted sex under pressure, said no to sex, used alcohol or partner used alcohol before sex. Strong associations were observed between each of the measures and sexual risk-taking for most of the indicators. Strongest associations were found among sexually active students high on both sensation seeking and impulsive decision-making and weakest associations among students low on both measures. Implications for design of interventions in health campaigns are discussed.     

The Crossroads of Countertransference and Attribution Theory: Reinventing Clinical Training within an Evidence-Based Treatment World

Social Psychological research on Person Perception/Attribution Theory has concluded that an individual responds to interpersonal situations based upon their interpretation of the “nature” of that situation. For example, physically attractive people are often attributed niceness and capableness even without any basis in reality. The observer, guided by percepts cum attributions, may treat the attractive participant “as though” these qualities are about them rather than about the observer's internal bias. In psychoanalysis, this social phenomenon takes on individual meaning as countertransference. Therapists seem to experience irrational feelings during the psychotherapy exchange, which remain, whether or not the therapist is conscious of these responses or whether their technical objective includes or ignores their own transference. The attributional tendency to act upon these feelings “as though” they were wholly about the patient may lead to therapeutic disasters. Therefore, clinical training of psychotherapists needs the early inclusion of this concept to prevent subsequent dogmatic and untherapeutic attitudes. This paper will discuss the possibility of disarming the damage rendered by medicalized parsimonious “healing” and the latest fashion, Evidence-Based Treatment, via a translation of assumedly unmeasurable psychoanalytic tenets into multiply measured, investigated areas of social research.     

The IPIP–HEXACO scales: An alternative, public-domain measure of the personality constructs in the HEXACO model

Recently, Lee and Ashton (2004) described the HEXACO Personality Inventory (HEXACO-PI), a new instrument designed to assess the six dimensions observed in lexical studies of personality structure of various languages. Here, we describe the development of an alternative measure of the HEXACO factors and their facets, using the items of the International Personality Item Pool (IPIP). The scales of the resulting IPIP–HEXACO inventory showed satisfactory psychometric properties, as assessed by internal-consistency reliability, convergent and discriminant correlations with the original HEXACO-PI scales, and factor structure. We discuss the potential usefulness of the new IPIP–HEXACO inventory and its strengths and limitations.     

The effect of rotation on configural encoding in a face-matching task

Inversion disrupts encoding of faces because of the disruption of configural encoding as evident in the Thatcher illusion (Thompson 1980, Perception 9 483-484). Here we consider the effect of rotation on the loss of configural encoding in a same/different matching paradigm. Participants decided whether two faces were of the same type (both normal or both Thatcherised) or not, at five angles of rotation (0 degrees, 45 degrees , 90 degrees, 135 degrees, 180 degrees). When the faces were both of the same person, the disruption due to rotation for 'same-type' judgments was linear and approximately equal for normal and Thatcherised face pairs. In experiment 2, with different-person face pairs, the effect of rotation was much greater for Thatcherised face pairs than for normal face pairs. These findings are in contrast to those reported by Boutsen and Humphreys (2003, Quarterly Journal of Experimental Psychology A 56 955-975), and reasons for these differences, along with implications, are discussed.