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61.
Hippocampal CA1 kindling but not long-term potentiation disrupts spatial memory performance 总被引:2,自引:0,他引:2 下载免费PDF全文
Long-term synaptic enhancement in the hippocampus has been suggested to cause deficits in spatial performance. Synaptic enhancement has been reported after hippocampal kindling that induced repeated electrographic seizures or afterdischarges (ADs) and after long-term potentiation (LTP) defined as synaptic enhancement without ADs. We studied whether repeated stimulations that gave LTP or ADs resulted in spatial performance deficits on the radial arm maze (RAM) and investigated the minimal number of ADs required for such deficits. Three experimental groups were run as follows: (1) 5 hippocampal ADs in 1 d (5-AD group), (2) 10 hippocampal ADs in 2 d (10-AD group), and (3) 12 -frequency primed-burst stimulations (PBSs) in 2 d in order to induce LTP without ADs (LTP group). Each experimental group was run together with a control group during the same time period. Rats were first trained in a spatial task on a radial arm maze with four of the eight arms baited, then given control or experimental treatment, and maze performance was tested in the first week (1-4 d) and fourth week (22-25 d) after treatment. Basal dendritic population excitatory postsynaptic potentials (pEPSPs) and medial perforant path (MPP)-evoked dentate gyrus population spike and polysynaptic CA1 excitation were recorded before and after experimental and control treatment. Spatial memory errors, in particular reference memory errors, were significantly higher in the 10-AD kindled group than any other group on the first and fourth week after treatment. Spatial memory errors were not significantly different in the 5-AD and LTP groups as compared with any control groups at any time. Basal dendritic pEPSP in CA1 was enhanced for about 1 wk after 12 PBSs, 10 ADs, or 5 ADs, while the dentate gyrus population spike and CA1 polysynaptic excitation evoked by MPP was increased for up to 4 wk after 10 ADs, but not 12 PBSs. Thus, distributed alteration of multiple synaptic transmission in the entorhinal-hippocampal circuit, but not LTP at the basal dendritic synapses in CA1, may disrupt spatial performance after 10 hippocampal ADs. 相似文献
62.
Farmer TW Price LN O'Neal KK Leung MC Goforth JB Cairns BD Reese LE 《American journal of community psychology》2004,33(1-2):51-59
Two studies were conducted to explore the degree to which single- and multiple-risk profiles were evident in samples of African American early adolescents in low-income inner-city, rural, and suburban schools. Study 1 examined early adolescent risk status (i.e., single, multiple) in relation to later adjustment in a representative sample (70% European American, 30% African American). Youth who experienced a single risk in early adolescence had moderately increased levels of school dropout and criminal arrests, whereas youth with multiple risks (i.e., combination of 2 or more risks) had significantly increased levels of school dropout, criminal arrests, and teen parenthood. Study 2 examined the extent to which single- and multiple-risk profiles were evident in cross-sectional samples of African American youth from low-income inner-city and rural areas. About one fourth of both the inner-city and rural samples of African American youth were composed of youth in the single-risk category. A significantly greater proportion of boys in the inner-city sample (20%) than boys in the rural sample (13%) experienced multiple risks. Girls across the rural and inner-city samples did not differ in terms of risk. Overall, more than 60% of African American youth in these two low-income samples did not evidence risk for later adjustment problems. Implications for research and intervention are discussed. 相似文献
63.
Net-generation attributes and seductive properties of the internet as predictors of online activities and internet addiction. 总被引:12,自引:0,他引:12
Louis Leung 《Cyberpsychology & behavior》2004,7(3):333-348
Born between 1977 and 1997, Net-generation is the first generation to grow up surrounded by home computers, video games, and the Internet. As children of the Baby Boomers, the Internet is the medium of choice for the Net-geners. Based on the assumption that Net-generation has unique characteristics, this study examined (1) how Net-geners addicted to the Internet differ from the non-addicted and (2) how these attributes, together with the seductive properties of the Internet, are related to Internet addiction. Data were gathered from a probability sample of 699 Net-geners between the ages of 16 and 24. Results show that Net-geners addicted to the Internet tend to be young female students. Being emotionally open on the Net and a heavy user of ICQ were most influential in predicting Net-geners' problematic use of the Internet. Addicted Net-geners are also strongly linked to the pleasure of being able to control the simulated world in online games. The finding reinforces previous research that "dependents" of the Internet spend most of their time in the synchronous communication environment engaging in interactive online games, chat rooms, and ICQ for pleasure-seeking or escape, while "non-dependents" use information-gathering functions available on the Internet. Furthermore, Internet addicts tend to watch television significantly less, indicating a displacement effect on traditional media use for the Net-generation. 相似文献
64.
Nerella V Ramanaiah Thomas Schill Lock Sing Leung 《Journal of research in personality》1977,11(2):251-259
This paper presents the results from two related studies concerning the internal structure of the Marlowe-Crowne Social Desirability (MD-SD) scale. Study 1 tested the hypothesis that attribution and denial are two major components of the MC-SD scale by factoring the intercorrelations among the MC-SD items using the correlated multiple-group common factor analysis, and the results supported the hypothesis. Study 2 investigated the differential validity of these components for predicting scores on the Lie scale, the K scale, and the Repression-Sensitization scale. The attribution and denial components were found to be differentially related to the K scale and the Repression-Sensitization scale but not the Lie scale. These results were also interpreted as partially supporting the hypothesis. 相似文献
65.
The Child Altruism Inventory (CAI) consisted of 24 yes-or-no items which measured the altruistic orientation of children. The sample included 1095 Grades 2 to 6 Chinese children in Hong Kong, The test-retest and internal consistency reliabilities of the CAI were in the 0.70s. The correlations of the CAI score with the intelligence and self-esteem scores were significantly positive, while the correlations of the CAI score with the psychoticism and neuroticism scores were significantly negative. Children in classes of positive and negative social environment rated high and low on the CAI respectively. The relations of the CAI score with self-report prosocial and delinquent behavioural indices were also positive and negative respectively. The psychometric properties of the CAI are regarded as quite good. 相似文献
66.
Siu -Luen Luk Patrick Wing -Leung Leung John Bacon-Shone Felice Lieh-Mak 《Journal of abnormal child psychology》1991,19(2):219-232
Nearly all 3-year-old Chinese children in Hong Kong attend preschool facilities, making it possible to study their behavior in a group learning situation based upon teachers' perception. The Preschool Behavior Checklist (PBCL), a teacher's questionnaire, was applied to a random sample of 851 Chinese children, ages 36 to 48 months. The factor structure of the PBCL was very similar to that obtained from its original British study, supporting its usage cross-culturally. Prevalence of behavior disorder was high as defined by the PBCL. This reflected specific cultural demands at school settings. Significant sex differences were also found in the overall rate of behavior disorder and symptom patterns. As in other studies, boys had more hyperactive, conduct, and speech problems. The results suggested a certain degree of universality of symptomatology for children at the preschool level.This project was funded by the Hong Kong Society for Child Health and Development. We are grateful to all the kindergartens and child care centers which participated in this project. Valuable assistance was provided by the Education Department and the Medical Health Department. 相似文献
67.
An ontology of information belies our common intuitions about reality today and animates and governs both explicit scholarly study in philosophy and the sciences as well as the ideologies that are growing out of them. Transhumanism is one such technoscientific ideology that holds to a very specific ontology of information which need not be the only one on offer. This article argues that the transhumanist ontology of information exhibits gnostic and docetic religious overtones in it and that it devalues physical existence. At the same time, despite claiming a rejection of supernature, hypothetical transhumanist practices (such as mind-uploading) posit the infosphere as a kind of supernatural realm that is often set in opposition to the natural world. This article presents a critique of transhumanist conceptions of information and offers an alternative ontology of information that more adequately accounts for the distinction between the natural and supernatural as well as the integrity of the physical world. 相似文献
68.
Moos and Moos' (1986) Family Environment Scale (FES) was adapted to the Chinese children and adolescents in Hong Kong. The major sample included 1,174 subjects from three elementary schools and seven high schools. Two subscales, Expressiveness and Independence and a few items were deleted based on the psychometric analysis. The FES scale intercorrelations were consistent, and the factor pattern of the remaining eight scales was explicable in terms of the characteristics of the Chinese culture. Results also showed that middle class families in general had a more positive family social environment than the working class families. 相似文献
69.
The Voting Propensity of Hong Kong Christians: Individual Disposition, Church Influence, and the China Factor 总被引:1,自引:0,他引:1
Considering China's history of unfavorable treatment of mainland Chinese Christians, the authors hypothesize that Christians in Hong Kong reflected their concern over the future protection of religious freedom during the 1995 Legislative Council election, the last election before the handover of the British colony to Chinese sovereignty. We have looked at the relative contributions of individual disposition, the China factor and church influence on the presence of Hong Kong Christians at the polling booth on election day. Our analysis found that Hong Kong Christians are subjected more to the influenceof the latter two factors. The influence of socio-economic status is relatively unimportant in determining the voting propensity of Hong Kong Christians. While both Catholics and Protestants are influenced by general church teachings, this research found that Catholic voters, are more subject to their church's organizational mobilization than Protestant voters. 相似文献
70.
Divergent consequences of success and failure in japan and north america: an investigation of self-improving motivations and malleable selves 总被引:8,自引:0,他引:8
Heine SJ Lehman DR Ide E Leung C Kitayama S Takata T Matsumoto H 《Journal of personality and social psychology》2001,81(4):599-615
Self-enhancing and self-improving motivations were investigated across cultures. Replicating past research, North Americans who failed on a task persisted less on a follow-up task than those who succeeded. In contrast, Japanese who failed persisted more than those who succeeded. The Japanese pattern is evidence for a self-improving orientation: Failures highlight where corrective efforts are needed. Japanese who failed also enhanced the importance and the diagnosticity of the task compared with those who succeeded, whereas North Americans did the opposite. Study 2 revealed that self-improving motivations are specific to the tasks on which one receives feedback. Study 3 unpackaged the cultural differences by demonstrating that they are due, at least in part, to divergent lay theories regarding the utility of effort. Study 4 addressed the problem of comparing cultures on subjective Likert scales and replicated the findings with a different measure. 相似文献