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Understanding the function of the distinct amygdaloid nuclei in learning comprises a major challenge. In the two studies described herein, we used c-Fos immunolabeling to compare the engagement of various nuclei of the amygdala in appetitive and aversive instrumental training procedures. In the first experiment, rats that had already acquired a bar-pressing response to a partial food reinforcement were further trained to learn that an acoustic stimulus signaled either continuous food reinforcement (appetitive training) or a footshock (aversive training). The first training session of the presentation of the acoustic stimulus resulted in significant increases of c-Fos immunolabeling throughout the amygdala; however, the pattern of activation of the nuclei of the amygdala differed according to the valence of motivation. The medial part of the central amygdala (CE) responded, surprisingly, to the appetitive conditioning selectively. The second experiment was designed to extend the aversive versus appetitive conditioning to mice, trained either for place preference or place avoidance in an automated learning system (INTELLICAGE). Again, much more intense c-Fos expression was observed in the medial part of the CE after the appetitive training as compared to the aversive training. These data, obtained in two species and by means of novel experimental approaches balancing appetitive versus aversive conditioning, support the hypothesis that the central nucleus of the amygdala is particularly involved in appetitively motivated learning processes.  相似文献   
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The article deals with the philosophy of Nikolai Berdjaev (1874–1948), which he formulated between The Philosophy of Inequality (written in 1918, but published in 1923) and The New Middle-Ages (1924). Berdjaev’s philosophy is analyzed in the context of the Russian Revolution of 1917 and its aftermath. The other point of reference is the crisis of culture and civilisation, which affected the West in the inter-war period. Berdjaev’s position has been interpreted in view of the archetypal myth of the struggle of the two principles, the principle of order (cosmos) and the forces of destruction (chaos). This myth is tied to the millenialist world view. Berdjaev took an anti-utopian stance. He juxtaposed the utopian-revolutionary principle with the hierarchical-creative one. From this position he criticized among others democracy, liberalism and socialism. In the midst of the crisis of the 1920s he remarked the possibility of spiritual rejuvenation putting forward the concept of the New Middle-Ages. One can say that at that time Berdjaev’s philosophy evolved within the conservative-creative framework, from the utopia of conservatism to the utopia of ‘free creativity’.  相似文献   
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Studies in Philosophy and Education - The current heated debate on the deteriorating status of the university raises a range of pertinent questions, including: What role can the humanities play in...  相似文献   
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