Cholinergic rebound after chlorpromazine exacerbates lithium muscarinic-induced limbic seizures in rats: implications for psychiatric treatment.

When lithium serum levels were within the (human) therapeutic range, young and old adult male and female rats (housed singly or in groups) all displayed faster limbic seizure onset times in response to a muscarinic cholinergic agonist (pilocarpine 20 mg/kg) if a single systemic dosage of chlorpromazine was injected 24 hours previously. The effect was comparable to injecting an additional 10 mg/kg of pilocarpine. These results strongly suggest that cholinergic rebound from chlorpromazine administrations during lithium treatment could facilitate subclinical electrical lability and very localized neuronal necrosis within the limbic system of clinical patients, resulting in normalization of psychiatric symptoms.     

Suicides in active-duty enlisted Navy personnel.

Cases of completed suicide among U.S. Navy enlisted personnel occurring from 1974 through 1985 were identified and compared with similar rates in the U.S. general population and in the U.S. Army. Although the Navy suicide rate was the lowest of the three groups, this rate increased between 1976 and 1983. This was in contrast to national and Army trends during the same period. Young white males in the apprentice/recruit and blue-collar occupations had the highest rates of completed suicide in the Navy. Recommendations for prevention and treatment are discussed.     

Strategy changes in human contingency judgments as a function of contingency tables.

Judgment strategies of 169 undergraduate students on problems to judge the contingency between two binary events were identified by the method of rule-based analysis to clarify whether or not the strategies the subjects used would be affected by the concrete nature of the contingency table. Problems were constructed along two factors: total cell frequency and width of range of objective contingencies. Although the factor of total cell frequency had no effect on subjects' strategies, the number of subjects who changed strategies corresponding with problem instances increased when the objective contingencies were set closer to zero or when problems became more difficult. These results are discussed in the context of previous studies of this issue in the literature.     

Odogenic change of blood coagulation in humans.

The blood coagulation time as an integral sign of human homeostasis is revealed to be influenced by conscious or unconscious olfactory stimuli through autonomic mechanisms. The hemostasis of subjects with predominance of sympathetic activity is more sensitive to the olfactory stimuli than that of subjects with vagal prevalence. The effects of the olfactory stimuli upon hemostasis in humans support the viewpoint that simultaneous information and physico-chemical processes act together in parallel to play and important role in life activities of human organism (Simonov, 1981; Sudakov, 1995). Emotions, therefore, are essential in the transfer of information from the environment (Anokhin, 1966; Miltner et al., 1994). It is not excluded that even very weak stimuli which are subthreshold for conscious perception might be informational for the organism as those engaging emotional response.     

A grouping interpretation of the modality effect in immediate probed recognition

In a series of experiments on immediate probed recognition for eight 3-digit numbers, it was shown that if the target modality involved auditory components and the effect of the similarity of the modality of the probe to that of the targets was controlled, unequivocal evidence was obtained for an auditory superiority effect (modality effect) for hit rates for the final items of the list. Moreover, false-alarm rates were significantly lower following targets with an auditory component than they were following silently seen targets. It is argued that this pattern of hits and false alarms is consistent with the idea that targets that have an auditory component yield memory representations that are better grouped as units than are those for targets that are only silently seen; in particular, if a new probe has a first digit that accidentally matches the first digit of a target item, it is more likely that the subject will mistakenly identify this new probe as old (give a false alarm) if the target has only been partially encoded because it was only silently seen.     

Early metalinguistic competence: speech monitoring and repair behavior.

This article examines 2-3-year-olds' responses to specific (e.g., "Where did he go?") and neutral (e.g., "What?") requests for clarification. The focus is on children's ability to locate the linguistic errors that provoked neutral questions of clarification and their success in providing appropriate repair. It is argued that this behavior provides evidence for a speech monitor that detects errors and enables repair. Contrary to A. Karmiloff-Smith's (1992) claim, control over the production and comprehension of specific structures does not necessarily precede monitoring. Rather, metalinguistic abilities that are implicated in speech monitoring develop simultaneously with the acquisition of primary linguistic behavior and do not require awareness. It is claimed that such metaprocesses are fundamental to the use of language as a vehicle for the expression of intentional content.     

Personality and Attraction to the Charismatic Movement: a study among Anglican clergy

A sample of 172 male clergy within the Church of England completed the Eysenck Personality Questionnaire together with an index of charismatic experience. The data demonstrate that charismatic experience is positively associated with extroversion, but related to neither neuroticism nor psychoticism.     

Impact of practice on speed of mental rotation

We tested 11- and 20-year-olds on 3360 trials of a mental rotation task in which they judged if stimuli presented in different orientations were letters or mirror images of letters. Children's and adults' processing times decreased substantially over practice. These changes were well characterized by hyperbolic and power functions in which most of the parameters of those functions were constrained to adults' values. Performance on two transfer tasks, mental rotation of letter-like characters and memory search for numbers, indicated that the practiced skill did not generalize to other domains. The results are discussed in terms of different mechanisms that might be responsible for the impact of practice.