Self-reference and emotional memory effects in older adults at increased genetic risk of Alzheimer’s disease

The present study investigated whether cognitively healthy older adults who are carriers of the ε4 allele of apolipoprotein E, the most prevalent genetic risk factor for late-onset Alzheimer’s disease, benefit from self-referential processing and emotional processing to the same degree as noncarriers of this gene. Participants encoded emotional and nonemotional narratives using a baseline-orienting task, semantic elaboration, or imagination-based self-referential processing and then completed a recognition memory test. Both groups of older adults showed enhanced recognition memory for narrative information following self-referential processing relative to semantic elaboration, and the magnitude of this memory effect was not affected by ε4 status. However, older adult ε4 carriers did not show an emotional enhancement effect, whereas older adult ε4 noncarriers did. These results indicate that whereas the self-reference effect is not attenuated in cognitively healthy older adults ε4 carriers, deficits in emotional memory may be an early cognitive marker of abnormal decline.     

Goal-relevant situations facilitate memory of neutral faces

Emotional situations are typically better remembered than neutral situations, but the psychological conditions and brain mechanisms underlying this effect remain debated. Stimulus valence and affective arousal have been suggested to explain the major role of emotional stimuli in memory facilitation. However, neither valence nor arousal are sufficient affective dimensions to explain the effect of memory facilitation. Several studies showed that negative and positive details are better remembered than neutral details. However, other studies showed that neutral information encoded and coupled with arousal did not result in a memory advantage compared with neutral information not coupled with arousal. Therefore, we suggest that the fundamental affective dimension responsible for memory facilitation is goal relevance. To test this hypothesis at behavioral and neural levels, we conducted a functional magnetic resonance imaging study and used neutral faces embedded in goal-relevant or goal-irrelevant daily life situations. At the behavioral level, we found that neutral faces encountered in goal-relevant situations were better remembered than those encountered in goal-irrelevant situations. To explain this effect, we studied neural activations involved in goal-relevant processing at encoding and in subsequent neutral face recognition. At encoding, activation of emotional brain regions (anterior cingulate, ventral striatum, ventral tegmental area, and substantia nigra) was greater for processing of goal-relevant situations than for processing of goal-irrelevant situations. At the recognition phase, despite the presentation of neutral faces, brain activation involved in social processing (superior temporal sulcus) to successfully remember identities was greater for previously encountered faces in goal-relevant than in goal-irrelevant situations.     

Development Projects and Life Satisfaction: An Impact Study on Fair Trade Handicraft Producers

Is there a correspondence between subjective and objective wellbeing indicators in development programs? We investigate this question by evaluating the impact of Fair Trade affiliation on the subjective wellbeing of a sample of Peruvian (treatment and control) producers from two different Fair Trade projects in two socioeconomic environments, one relatively poorer (Juliaca) and the other relatively more affluent (Chulucanas). We find a direct and an indirect effect. The direct effect acts positively via affiliation years in the poorer project and via trade diversification in both projects. The indirect effect acts through the reduction of poverty and relative income. Consistently with the concave income-happiness assumption, the variables generating the indirect effect have a much weaker impact for producers living in the relatively better-off socioeconomic environment, net of the lower FT economic impact in this area.     

Suicidality in African American men: the roles of southern residence, religiosity, and social support

The rise in suicide by African Americans in the United States is directly attributable to the dramatic, nearly three-fold increase in suicide rates of African American males. Gibbs (1997) hypothesized high social support, religiosity, and southern residence are protective factors against suicidality for Black people. This hypothesis was tested among 5,125 participants from the National Comorbidity Survey; 299 were African American males. In this study we hypothesized that there would be significantly lower suicidality in the South, and social support and religiosity would mediate this relationship. Our results indicate that Southern region is indeed a significant predictor of suicidal symptoms in African American men, such that suicidal symptoms were lower in the South, but religiosity and social support did not account for this effect. Other potential mediators were also examined.     

Use of anvils by the Great Kiskadee (Aves,Tyrannidae): a description based on citizen science data

Animal Cognition - The use of anvils to strike prey is a behavior observed in some species of birds around the world. Here, I investigated the use of anvils by the Great Kiskadee (Pitangus...     

Reliability and acceptability of web-based administration of Spanish ages and stages questionnaires third edition®

to analyse the reliability of 6 age intervals of Spanish web-based Ages and Stages Questionnaires Third Edition (WB-ASQ-3) and parents' acceptability, in a clinical practice context, during COVID-19 pandemic and lockdown in Chile. Cross-sectional study with a longitudinal component. Internal consistency was analysed by Cronbach's alpha and Pearson product–moment correlation, Pearson's correlations between intervals questionnaires were analysed. Acceptability was determined using a parental satisfaction survey. 1061 children completed 2318 validated questionnaires. Scores were compared with normative sample, except for Gross motor at 8 and 12 months, and Communication at 12, 18 and 24 months, without differences to the previous Chileans sample. In domain analysis, Cronbach's alpha ranged from 0.36 to 0.80 and reached 0.74 to 0.81 for the overall test. Strong positive correlation between the domain and overall score was obtained. Correlation between most questionnaires at different ages was positive and significant. Parental surveys show high satisfaction; parents were thankful for being able to monitor children's development. WB-ASQ-3 is a reliable and feasible screening system, particularly when the test is taken as a whole, rather than by domains. It is remarkably high acceptability among parents, especially in complex times such as the lockdown and the COVID-19 pandemic.     

Social anxiety and problematic cannabis use: evaluating the moderating role of stress reactivity and perceived coping

Despite epidemiological reports indicating an association between social anxiety disorder (SAD) and cannabis use disorders (CUD), there is a paucity of research exploring the nature of this relationship. The present investigation examined potential moderators of this relationship that are consistent with a tension-reduction model of addiction. Specifically, physiological reactivity to stress and perceived coping with stress were evaluated as moderators of the relation between symptoms of SAD and CUD. Physiological (SCR) and subjective (perceived coping) responses to unpredictable white noise bursts were collected from non-clinical participants (n=123). Lifetime symptoms of CUD and anxiety disorders were assessed using a structured diagnostic interview. CUD symptomatology was associated with symptoms of SAD but not with symptoms of any other anxiety disorder. Only perceived coping to unpredictable stimuli moderated the relationship between SAD and CUD symptoms. Findings are discussed in the context of tension-reduction models of co-occurring social anxiety and problematic cannabis use.     

Automated assessment of conditioning parameters for context and cued fear in mice

A behavioral technique often used to evaluate the cognitive performance of rats and mice is the fear conditioning paradigm. During conditioned fear experiments, freezing responses shown by rodents after exposure to environmental stimuli previously paired to an aversive experience provide a behavioral index of the animal's associative abilities. The present study examined the ability of a computer-controlled automated Freeze Monitor system for recording immobility behavior in mice. The sensitivity of the automated procedure to detect group differences caused by the application of various training protocols was also evaluated. Statistical analyses revealed significant positive correlations between immobility scores obtained with the automated apparatus and hand-scored data collected by a continuous or a time-sampling method. Behavioral patterns recorded by the computerized system were very similar to those obtained by the hand-scoring methods adopted. In particular, during context testing, exposure to environmental stimuli previously paired with a mild foot shock (unconditioned stimulus [US]) evoked increased immobility behavior in mice conditioned with the US compared with levels of immobility displayed by mice previously confined to the same contextual stimuli without receiving the US. Moreover, although during conditioned stimulus (CS) testing, mice previously exposed to the US displayed high levels of immobility when confined to environmental cues much different from those paired with the US (contextual fear generalization), both hand-scored and automated results revealed the effect of CS–US pairing (increased immobility) only in mice trained to associate the two stimuli (paired group) but not in mice exposed to both CS and US separated by a 40-sec time interval (unpaired group) or in mice receiving only the US (US group) during conditioning sessions. Overall, the results show associative conditioning measured in an automated apparatus and highlight the utility of obtaining both latency as well as beam interruption parameters.     

Family Economic Well-Being,and (Class) Relative Wealth: An Empirical Analysis of Life Satisfaction of Secondary School Students in Three Italian Cities

The aim of the study is to shed light on an under-investigated topic—the determinants of life satisfaction of the young—by means of an econometric analysis which focuses specifically on the relationship between household wealth and life satisfaction of secondary school students living in three Italian cities: Rome, Milan and Genoa. We find that family home ownership, mortgages and (class) relative wealth significantly affect the life satisfaction of students. Other significant controls are geographical residence (those living in Milan are significantly less satisfied with life), the mother’s occupation, and trust in family and friendships. The characteristics of our household wealth variables make it hard to conceive any inverse causality (and endogeneity highly unlikely), thus suggesting a direct causality nexus for these factors. We explain why our research provides important insights that should be taken into account when developing policies to promote the subjective well-being of the young.