Effects of intrahemispheric interference on reaction times to lateral stimuli

Earlier work (Green, 1977) indicated that response by a given hand was slower when stimuli occurred in the visual half field ipsilateral to the body side of hand origin. It was hypothesized that this was due to interference between processing demands originating within the same hemisphere. The present experiments provide evidence regarding the relationship between such interference and the magnitude and type of processing demands. The eight experiments indicate that intrahemispheric interference affects a variety of tasks, including letter shape, letter name, or face matching. The results indicate that reduction in response processing demands reduces the interference. Evidence of interference appeared with a more demanding choice response, but not with a simpler go-no-go response. Manipulations hypothesized to reduce initial, perceptual stimulus processing demands did not reduce the magnitude of interference, possibly because the level of more central stimulus processing demands was still sufficient to interfere with response processing. Interference tended to be minimal on right-hand, match trials, which are hypothesized to involve reduced response processing and reduced central stimulus processing demands. Further investigation of the effects of stimulus processing demands is required.     

Evidence for the involvement of brain GABA and serotonin systems in the anticonflict effects of chlordiazepoxide in rats

Using male hooded Lister rats the effects of GABAergic and serotonergic treatments alone and with chlordiazepoxide (CDP) were compared with the behavioral effects of CDP in a conditioned conflict procedure with three components; Reward, Time Out, and Conflict. CDP (2.5, 5.0, and 10.0 mg/kg ip) dose- relatedly increased punished and time out responding, but increased rewarded responding in an inversely dose-related manner. Punished responding was enhanced by chronic treatment to a rate which remained stable between 9 and 19 injections. The GABA transaminase inhibitor ethanolamine-O-sulfate (EOS), given chronically in drinking water (5.0 mg/ml), increased punished responding linearly to a high stable level after 2-3 weeks. Rewarded and time out responding were less substantially increased. CDP given with EOS dose- relatedly increased time out and punished responding substantially above the rates found with either treatment alone. The GABA antagonist picrotoxin blocked the increase in punished and time out responding found with EOS and CDP alone. The tryptophan hydroxylase inhibitor p-chlorophenylalanine (PCPA; 100 mg/kg x 3) linearly increased punished responding for the first week of treatment. CDP with PCPA selectively and significantly increased punished responding above the rates for either treatment alone, but the increases were not as substantial as those with EOS + CDP. The serotonin reuptake inhibitor Wy 25093 reduced increases in time out and punished responding under CDP, and the precursor 5-hydroxytryptophan (5-HTP) counteracted increases in punished responding under PCPA but also substantially reduced rewarded responding. These results provide evidence that both increased GABA and decreased serotonin transmission are involved in the anticonflict effects of CDP, as EOS and PCPA both mimicked and potentiated effects of CDP, while picrotoxin, Wy 25093, and 5-HTP counteracted them.(ABSTRACT TRUNCATED AT 250 WORDS)     

Error patterns in a chord keyboard response task

Errors in a serial choice-reaction time experiment employing two-finger chord responses to alphabetic stimuli are shown to be distributed in a significantly non-random fashion. Two factors are postulated which are relevant to prediction of the error response. These are the presence or absence of a common finger, and the difference in finger separation, between the actual and the required response. It is suggested that the chord response is coded in terms of a pattern (the distance between the two response components). Responses which mirror the correct response about the centre of the hand are also shown to be significantly more frequent.     

Book reviews

Encyclopaedia of Linguistics, Information and Control. Edited by A. R. Meetham with the assistance of R. A. Hudson. Oxford: Pergamon Press. 1969. Pp. xiv + 718. 300s.

The Biological Basis of Personality. By H. J. Eysenck. Springfield: Thomas. 1968. Pp. xv + 399. $18.50.

Scientific Basis of Dvug Dependence. Biological Council Symposium. Edited by H. Steinberg. London: Churchill. 1969. Pp. 429. 100s.

Minnesota Symposia on Child Psychology, Vol. 2. Edited by John P. Hill. Minneapolis: University of Minnesota Press. 1969. Pp. viii + 172.

Memory and Attention: an introduction to human information processes. By Donald A. Norman. Chichester, Sussex: John Wiley. 1969. Pp. ix + 201. 84s. (cloth); 44s. (paper). Verbal Learning and Memory: selected readings. By Leo Postman and Geoffrey Keppel. Harmondsworth: Penguin Books. 1969. Pp. 501. 12s.

Handbuch der Kinderheilkunde. Edited by H. Opitz and F. Schmidt. Rand VIII/I: Neurologie-Psychologic-Psychiatrie. Redigiert von F. Schmidt und H. Asperger. Berlin: Springer Verlag. Pp. 1060. Price DM385, S96.25.

Digital Computing. By R. S. Lehman and D. E. Bailey. London: John Wiley & Sons Ltd. 1969. Pp. xxiv + 303. 79s.

Real-Time Computers. By W. R. Uttal. New York: Harper & Row. 1968. Pp. xiv + 338. 93s.     

Detection of auditory signals presented at random times

One hundred msec tones of 1000 Hz at four intensities were presented according to two Poisson schedules in a background of wide band noise and as increments to a 1000 Hz tone. Each 15 minute test session was run under fixed conditions and one of three instructions to detect the signals; the two Ss were free to respond at any time. The data analyzed were several inter-response and signal-response distributions, and they were compared with a theory due to Luce. Discrepancies between the theory and data indicate needed modifications of both the theory and the procedure.