The Convention on Human Rights and Biomedicine of the Council of Europe

The Convention on Human Rights and Biomedicine developed by the Council of Europe, now undergoing ratification, is the first international treaty focused on bioethics. This article describes the background of the Convention's development and its general provisions and provides a comparison of its requirements with those of federal regulations governing research with human subjects. Although most provisions are comparable, there are significant differences in scope and applicability, for example, in the areas of compensation for injury, research participation by persons with limited capacity to consent, assisted reproduction, organ transplantation, and research in emergency situations. The Convention represents a milestone in international bioethics and protection of human rights that will probably be referred to with increasing frequency.     

Abstraction Processes in Artificial Grammar Learning

Four experiments explored the extent to which abstract knowledge may underlie subjects' performance when asked to judge the grammaticality of letter strings generated from an artificial grammar. In Experiments 1 and 2 subjects studied grammatical strings instantiated with one set of letters and were then tested on grammatical and ungrammatical strings formed either from the same or a changedletter-set.Evenwith a change ofletter-set, subjects were found to be sensitive to a variety of violations of the grammar. In Experiments 3 and 4, the critical manipulation involved the way in which the training strings were studied: an incidental learning procedure was used for some subjects, and others engaged in an explicit code-breaking task to try to learn the rules of the grammar. When strings were generated from a biconditional (Experiment 4) but not from a standard finite-state grammar (Experiment 3), grammaticality judgements for test strings were independent of their surface similarity to specific studied strings. Overall, the results suggest that transfer in this simple memory task is mediated at least to some extent by abstract knowledge.     

ASSOCIATIVE PROCESSES IN FALSE RECALL AND FALSE RECOGNITION

Abstract— Studying a list of words associated to a critical nonpresented word results in high rates of false recall and false recognition for that nonpresented item (Roediger & McDermott, 1995) Two experiments examined the effect of manipulating the number of associates presented on false recall and later false recognition of a nonpresented item. In Experiment 1, associate lists of varying lengths were studied, in Experiment 2, list length was held constant and the number of associates within the list was manipulated. In both experiments, the rate of critical intrusions in recall increased steadily with increasing number of associates studied Most notably, the filler words used in Experiment 2 to equate the list lengths did not affect the rate of critical intrusions, although they did depress recall of studied words. False recall and false recognition appear to be tied to the total, not the mean, associative strength of items in the list.     

Cognitive sequelae of repeated head injury in a population of intravenous drug users

The relationship between closed head injury and performance on neuropsychological (NP) tests was investigated in a group of intravenous drug users (IVDUs). Subjects with repeated head traumas involving loss of consciousness (LOC) performed worse than both a control group without LOC and reference group with only a single episode of LOC. There were no significant differences between the last two groups. Performance on tests of memory, attention, and motor performance was significantly worse in the group with repeated head injury. The average time since the last episode of LOC was more than 11 years. We conclude from these findings that a single episode of LOC does not result in significant cognitive impairment in this population. Two or more episodes, however, are more likely to produce chronic cognitive impairment.     

On the nature of meaning and its indeterminacy: Davidson''s view in perspective

In order to illustrate the nature of the indeterminacy of meaning, Donald Davidson sometimes compares it to the fact that we can measure length or temperature on different scales. In the following paper I try to explain first why we are supposed to expect such an analogy, given the semantics of the word meaning and of the word length or temperature. In the second part I examine how close the analogy is by distinguishing different forms of indeterminacy of meaning (viz., the indeterminacy of reference and the indeterminacy of truth) and ask whether both forms have an equivalent in a theory of measurement. I shall conclude that this is indeed the case.I would like to thank an anonymous reviewer for his or her detailed comments on a first version of this paper, which helped me to clarify my views considerably.     

PHONOLOGICAL CODES ARE AUTOMATICALLY ACTIVATED DURING READING:

Abstract— Subjects read sentences containing target words that were homophones (words with a single pronunciation but different spellings) while their eye movements were recorded A prime word was presented briefly at the onset of fixation on the target region The prime for a given target (e g, beach) was either identical to the target (beach, a phonologically similar word (the homophone beech), a visually similar nonhomophone (bench), or a dissimilar word (noise) Phonological priming effects were assessed by comparing fixation times on the target when It was preceded by the homophone versus the visually similar word Results suggest that phonological codes are automatically activated during eye fixations in reading     

The Fire Chief microworld generating program: An illustration of computer-simulated microworlds as an experimental paradigm for studying complex decision-making behavior

Computer-simulated microworlds bridge the gap between the complexity of field investigations and the rigor of laboratory studies. The purpose of this paper is to draw attention to the major methodological issues involved in developing and using computer-simulated microworlds for the psychological study of complex decision-making behavior. These issues comprise flexibility and generality in the microworlds that can be created, adequate psychological validity, automatic trial administration and data logging, capacity to interface simulations of psychological processes, and adequate testing and documentation. Each of these issues is illustrated by indicating how it has been addressed in Fire Chief, a microworld generating program specifically designed for creating realistic, yet controllable, decision-making task environments in the psychology laboratory. Fire Chief (Omodei & Wearing, 1993a) is introduced as both fully portable to other research teams and suitable for use in many different contexts requiring a complex task situation.     

Delaying approval of a critical drug: Safety,efficacy, economics,compassion

Biotechnological advance is speeding the development of drugs. The approval processes for new drugs will inevitably involve a regulatory agency in making political-economic and scientific choices. Interests of specific patients and the public in general are to be considered, and enormous stakes are involved for companies concerned. A medical regulatory authority must be at once insulated from and responsive to many different mixes of singular and general interests and pressures. Access to new drugs can be spurred by the press of patient advocacy groups, but if there are well organized groups to monitor the testing and approval process for such as AIDS or cancer drugs there is often no similar group to represent patient needs. If there is no organized patient advocacy group, compassionate responsibility by a medical regulatory authority is indeed called for. Delay in the approval of new drugs for fighting severe blood infections raises the question of how to insure the compassionate responsibility of a regulatory authority.     

Preparing the Way: A Qualitative Study of High-Achieving African American Males and the Role of the Family

Employed qualitative methods to examine the role of the family in the academic success of very high-achieving African American males. Findings revealed a complex tapestry of family processes and contexts involved in each youth's journey to outstanding academic achievement. Specifically, the combined importance of parental-determined academic engagement, strict discipline, nurturance, and community connectedness appeared to counteract potentially negative contextual influences of neighborhood, peers, schools, and society. The qualitative findings tell a multifaceted, rich, and compelling story of the pathways to academic success for Black males, and highlight the need for culture-specific and ecologically based conceptualization, research, and intervention approaches.     

The Impact of Sex and Gender Role Self-Perception on Affective Reactions to Different Types of Film

To what extent do differences in biologicalsexand psychological gender identity influence affectivereactions to different genres of film? In order toaddress this question, this investigation examined the impact of sex and gender roleself-perceptions on viewers' responses to neutral,melodramatic, and violent film segments. Working with apredominantly Caucasian population (93% Caucasian) at asoutheastern university, the results emphasize theimportance of sex and gender role self-perceptions onviewers' affective responses to media entertainment. Theimplications of these findings are discussed.