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91.
Adrenergic nervous system alteration and ethanol-induced narcosis in long-sleep and short-sleep mice
Long-sleep (LS) and short-sleep (SS) mice were pretreated with either propranolol or phentolamine, followed by a hypnotic dose of ethanol. Pretreatment with propranolol, but not phentolamine, significantly reduced ethanol sleep time in LS mice. The SS mice were not affected. In a second study propranolol pretreatment was given subsequent to ethanol at various doses, different for each line, that produced similar sleep time durations in both lines. Under these conditions, propranolol decreased sleep time in both LS and SS mice. These data lend support to the idea that noradrenergic mechanisms play a role in the mediation of the hypnotic effects of ethanol. 相似文献
92.
Joan S. Girgus Stanley Coren Leah Horowitz 《Attention, perception & psychophysics》1973,13(1):157-160
Illusion decrement with prolonged inspection was used as a technique to assess the relative amount of central component in seven variants of the Mueller-Lyer illusion. Results indicate that all of the variant forms share a common, central component, while the peripheral components, such as lateral inhibition, vary as a function of the presence of converging lines in the illusion configurations. 相似文献
93.
Two investigations were conducted to determine the nature of the relationship between facial reactions and surprise and humor ratings as suggested by the facial feedback hypothesis. In the correlational investigation, individual subjects showed a positive correlation between their spontaneous facial reactions and funniness ratings over 36 cartoons (within subjects). Subjects who were facially more reactive to all the cartoons, however, did not rate them as funnier than did subjects who were less facially reactive (between subjects). In the experimental investigation, spontaneous facial reactions were evoked by a discrepant weight and also were inhibited or amplified on verbal demand. Surprise and funniness ratings varied with spontaneous facial reactions but were unaffected when those reactions were voluntarily inhibited or amplified. The results were interpreted as not supporting the facial feedback hypothesis and suggested that facial reactions may only correlate with emotional experience.These investigations were supported by Ball State University Research Grants. 相似文献
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Female odors evoke ultrasounds from male mice 总被引:1,自引:0,他引:1
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The transition from preschool to formal schooling constitutes an important developmental milestone for children and their
families. Very few empirical studies investigating the kindergarten transition for typically developing children have been
published, and fewer have examined transition experiences from the perspective of caregivers. The aims of our study were to
investigate: (1) parent concerns during transition, (2) perceived needs during transition, and (3) parent involvement in kindergarten
preparation activities. Parents/caregivers of 86 general education students transitioning to kindergarten completed a survey
assessing their concerns, needs, and involvement in transition preparation activities. Results suggest that although the majority
of parents expressed few concerns regarding their child’s kindergarten transition, a subset (i.e., 27.9%) reported significant
concerns. The areas of concern most often cited by families in this sample were socio-behavioral in nature. Parents in this
sample expressed a desire for various types of information during transition. Parents most often reported engaging in low
intensity transition practices characterized by generic forms of contact, rather than more individualized and intensive practices
often cited in the literature as best practices. In addition, parent involvement in transition preparation activities differed
by family socioeconomic status as well as district locale. This study offers practical suggestions and policy implications
for coordinating family and school efforts during children’s kindergarten transition. 相似文献
100.
McClimans L 《Theoretical medicine and bioethics》2011,32(6):389-401
Patient-reported outcomes are increasingly used as dependent variables in studies regarding the effectiveness of clinical
interventions. But patient-reported outcome measures (PROMs) do not provide intuitively meaningful data. For instance, it
is not clear what a five point increase or decrease on a particular scale signifies. Establishing ‘interpretability’ involves
making changes in outcomes meaningful. Attempts to interpret PROMs have led to the development of methods for identifying
a minimum important difference (MID). In this paper, however, I draw on Charles Taylor’s distinction between weak and strong
evaluations to suggest that identifying a MID, specifically, a MID that uses a patient-reported reference group, may not provide
an adequate interpretation of these measures. Moreover, I argue that the difficulty with interpreting these measures is tied
to a larger problem concerning their validity. If researchers wish to interpret PROMs, they may first need to know more about
the constructs they attempt to measure, namely, quality of life. 相似文献