Donation after circulatory death: burying the dead donor rule

Despite continuing controversies regarding the vital status of both brain-dead donors and individuals who undergo donation after circulatory death (DCD), respecting the dead donor rule (DDR) remains the standard moral framework for organ procurement. The DDR increases organ supply without jeopardizing trust in transplantation systems, reassuring society that donors will not experience harm during organ procurement. While the assumption that individuals cannot be harmed once they are dead is reasonable in the case of brain-dead protocols, we argue that the DDR is not an acceptable strategy to protect donors from harm in DCD protocols. We propose a threefold alternative to justify organ procurement practices: (1) ensuring that donors are sufficiently protected from harm; (2) ensuring that they are respected through informed consent; and (3) ensuring that society is fully informed of the inherently debatable nature of any criterion to declare death.     

Conservatism and cognitive ability

Conservatism and cognitive ability are negatively correlated. The evidence is based on 1254 community college students and 1600 foreign students seeking entry to United States' universities. At the individual level of analysis, conservatism scores correlate negatively with SAT, Vocabulary, and Analogy test scores. At the national level of analysis, conservatism scores correlate negatively with measures of education (e.g., gross enrollment at primary, secondary, and tertiary levels) and performance on mathematics and reading assessments from the PISA (Programme for International Student Assessment) project. They also correlate with components of the Failed States Index and several other measures of economic and political development of nations. Conservatism scores have higher correlations with economic and political measures than estimated IQ scores.     

McEwen-Induced Modulation of Endocrine History: A Partial Review

In endless facets of physiology, there are points of homeostatic balance, such that too much or too litttle of something can both be deleterious (i.e., an "inverse U" pattern). This is particularly true when considering glucocorticoids (GCs), the adrenals steroid secreted during stress. In the first part of this paper, I review a number of realms in which a paucity and an excess of GCs are both damaging. Some findings are classical (for example, concerning GC effects upon body weight), while some are quite recent and have considerable implications for both physiology and pathophysiology (for example, inverse U's of GC actions in the realm of immunity and neuronal survival). The second part of the review considers the far thornier issue of how such inverse U's of GC actions are generated on a cellular and molecular level. One solution that has evolved, primarily in the hippocampus within the nervous system, involves the presence of two different types of receptors for GCs within the same cells; so long as the two receptors have very different affinities and mediate opposing effects on some cellular endpoint, an inverse U will emerge. The second solution, found in a number of peripheral tissues, involves GCs having opposing effects on the amount of some signal being generated (e.g., an immune cytokine) and the sensitivity of target tissues to that signal; under conditions that appear to be physiologically relevant, inverse U's emerge from this pattern as well. The final section of this review considers the enormous role played by Bruce McEwen in the emergence of this literature. I suggest that while much of this obviously has to do with the facts that have come from his group, another substantial contribution is from his steadying and supportive personality, the veritable embodiment of homeostatic balance.     

Predicting behavior on a computer from intentions, attitudes, and experience

Research on computer attitudes has generally focused on describing the cognitive elements. The present study used the Ajzen and Fishbein model to predict intentions to work hard in a computer course and actual time on the computer. In addition, the influence of experience on predictions was examined. Results from 74 social science students showed that the Ajzen and Fishbein model is effective at predicting both intentions and behavior. Unlike previous findings, experience did not interact with attitudes. Finally, a short cognitive attitude scale was an additional significant predictor beyond intentions in explaining behavior variance.     

Auditory and visual factors of intelligence

In a sample of 241 convicts, most of whom were between 20 and 35 years of age, a sample of 18 primary mental abilities was factored to explore the idea that in performances that are believed to indicate human intelligence there are organizations among visual and auditory functions that operate independently from the relation-perceiving and correlate-educing functions of fluid and crystallized intelligence. Objectively rotated results suggest that, indeed, reliable overlapping (common-factor) functions of Auditory Acuity (Ac), Auditory Organization (Ga), Visual Organization (Gv), Acculturational Eduction (Gc) and Fluid Eduction (Gf) represent separate components of individual differences in performances on intellectual tasks broadly conceived.     

Infant habituation and generalization to differing degrees of stimulus novelty

This study examined 4-month-old infants' fixation times to familiar and novel visual patterns. Thirty-two male and 32 female infants were given 12 successive 15 sec exposures to one simple geometric pattern followed by test trials consisting of two exposures to the same pattern, two to a pattern with the same form but novel color, two with a novel form but the same color, and two with both novel form and color. Results indicated habituation of fixation times to the repeated stimulus and recovery to novel stimuli, particularly in male infants. Generalization was also obtained with less recovery to patterns with only one dimension novel than to those with both novel. Most individual infants were also found to be attending to both dimensions rather than some infants attending mainly to color changes and others attending mainly to form changes.