Patterns of neuropsychological performance in multiple system atrophy compared to sporadic and hereditary olivopontocerebellar atrophy

Although neuropsychological symptoms are associated with multiple system atrophy (MSA), sporadic olivopontocerebellar atrophy (sOPCA), and dominantly inherited olivopontocerebellar atrophy (dOPCA), the differences between these groups have not been explored. We compared 28 MSA patients on psychiatric rating scales and neuropsychological measures to 67 sOPCA patients, 42 dOPCA patients, and 30 normal controls. Patients with dOPCA, sOPCA, and MSA all exhibited significant deficits on motor-related tasks, as well as relatively mild deficits in cognitive functioning. Patients with MSA had greater neuropsychological dysfunction, particularly in memory and other "higher order" cognitive processes, than patients with either sOPCA or dOPCA.     

Peer functioning, family dysfunction, and psychological symptoms in a risk factor model for adolescent inpatients' suicidal ideation severity

Examined models of suicidal ideation severity that include two psychosocial risk factors (i.e., peer and family functioning) and four domains of psychological symptoms (i.e., generalized anxiety, depression, conduct problems, and substance abuse/dependence). Participants were 96 psychiatric inpatients (32 boys, 64 girls), ages 12 to 17, who were hospitalized because of concerns of suicidality. Adolescents completed a structured diagnostic interview, measures of suicidal ideation, and several dimensions of family and peer functioning. Results supported a model in which greater levels of perceived peer rejection and lower levels of close friendship support were associated directly with more severe suicidal ideation. In addition, indirect pathways included deviant peer affiliation and global family dysfunction related to suicidal ideation via substance use and depression symptoms. The results are among the first to demonstrate relations between suicidal ideation and several areas of adolescent peer functioning, as well as divergent processes for peer and family predictors of suicidal ideation.     

Aggression and self-esteem: a diary study of children's reactivity to negative interpersonal events

The study employs a daily diary design to assess self-esteem reactivity and its association with children's aggressive behavior. We test the hypothesis that the self-esteem of aggressive children will be more reactive to negative interpersonal events than the self-esteem of nonaggressive children. Results provide partial support for the aggression/reactivity hypothesis. Aggressive children's self-esteem was more reactive to negative peer events but less reactive to negative adult events than the self-esteem of less aggressive children. These findings are discussed in relation to the experimental literature relating self-esteem instability and ego-threat to aggression and in relation to the extensive body of research on childhood aggression. Intervention implications are also considered.     

Dana-Farber Cancer Institute ethics rounds: life-threatening illness and the desire to adopt

Originally presented during Ethics Rounds at the Dana-Farber Cancer Institute, this commentary on the case of a patient treated for life-threatening cancer explores the responsibilities of health care providers when addressing the patient's desire to adopt a child.     

Sex and the Barnum effect: rationality versus helpfulness

In 1998 Piper-Terry and Downey found that women accepted friends' bogus test interpretations more readily than did men and the researchers attributed this to women's helpfulness. Layne countered that women are more open and thus rationally expected their friends' interpretations to be more accurate. Later Downey asked participants how accurately they believed their friends could describe their personalities. Although this pilot study's sensitivity to differences was low, the women's accuracy ratings still tended to exceed those of men (p < .06) as Layne predicted. This may suggest that the rationality hypothesis is better supported than the female-helpfulness hypothesis.     

Abortion, Intimacy, and the Duty to Gestate

In this article, I urge that mainstream discussions of abortion are dissatisfying in large part because they proceed in polite abstraction from the distinctive circumstances and meanings of gestation. Such discussions, in fact, apply to abortion conceptual tools that were designed on the premiss that people are physically demarcated, even as gestation is marked by a thorough-going intertwinement. We cannot fully appreciate what is normatively at stake with legally forcing continued gestation, or again how to discuss moral responsibilities to continue gestating, until we appreciate in their own terms the goods and evils distinctive of gestational connection. To underscore the need to explore further the meanings of gestation, I provide two examples of the difference it might make to legal and moral discussions of abortion if we appreciate more fully that gestation is an intimacy.     

Professors are people too: The impact of informal evaluations of professors on students and professors

There are websites where individuals anonymously provide informal reviews of professors. What impact do such sites have on student and professor motivational factors? Research suggests that undergraduate students are affected (e.g. Edwards et?al. in J Comput Mediat Commun 14:368?C392, 2009; Kowai-Bell et?al. in Comput Hum Behav 27(5):1862?C1867, 2011). The goals of the present investigation are to (1) see if Master??s level students are also influenced and (2) investigate how professors are affected. We provided students (Study 1) and professors (Study 2) comments from an informal review website and they, respectively, took the perspective of a potential student or the professor described in the comments. In Study 1, consistent with prior research on undergraduates, Master??s level students were affected by the reviews (perceived control, outcome expectancies, affect toward taking the class, and likelihood of recommending to a friend), in accordance with the valence of the reviews. Among professors (Study 2), the valence of the reviews influenced affect and self-concept with respect to relational aspects of teaching (mood, affect toward teaching again, confidence that students liked them, and confidence that they would have rapport with future students) but did not have an effect on professor self-concept with respect to competence (teaching ability and teaching well in the future). Furthermore, preliminary evidence suggests that new professors are more susceptible than experienced professors. The results of these studies are relevant because of the degree to which students and instructors contribute to the socioemotional climate of the classroom (Frenzel et?al. in J Educ Psychol 103(3):705?C716, 2009; Radel et?al. in J Educ Psychol 102(3):577?C587, 2010).     

Small is beautiful: In defense of the small-<Emphasis Type="Italic">N</Emphasis> design

The dominant paradigm for inference in psychology is a null-hypothesis significance testing one. Recently, the foundations of this paradigm have been shaken by several notable replication failures. One recommendation to remedy the replication crisis is to collect larger samples of participants. We argue that this recommendation misses a critical point, which is that increasing sample size will not remedy psychology’s lack of strong measurement, lack of strong theories and models, and lack of effective experimental control over error variance. In contrast, there is a long history of research in psychology employing small-N designs that treats the individual participant as the replication unit, which addresses each of these failings, and which produces results that are robust and readily replicated. We illustrate the properties of small-N and large-N designs using a simulated paradigm investigating the stage structure of response times. Our simulations highlight the high power and inferential validity of the small-N design, in contrast to the lower power and inferential indeterminacy of the large-N design. We argue that, if psychology is to be a mature quantitative science, then its primary theoretical aim should be to investigate systematic, functional relationships as they are manifested at the individual participant level and that, wherever possible, it should use methods that are optimized to identify relationships of this kind.