The association between intelligence level and brain volume measures: a negative finding

Ratings of pre-morbid intelligence level, derived from the hospital charts of 26 chronic schizophrenics, were correlated with the post-mortem brain volume measures of cortex, white matter, central grey matter, and ventricles. Contrary to hypothesis, no significant correlations were found.     

Cerebral hemispheric mechanisms in the retrieval of ambiguous word meanings

Targets related to ambiguous primes were projected to the left and right visual fields in a lexical priming experiment with stimulus onset asynchronies (SOA) of 35 and 750 msec. Right visual field results were similar to our earlier results with central projection (G. B. Simpson & C. Burgess, 1985, Journal of Experimental Psychology: Human Perception and Performance, 11, 28-39). Facilitation was found for the more frequent meaning at both SOAs and a decrease in facilitation for the less frequent meaning at the longer SOA. In contrast, left visual field results indicated a decay of facilitation for the more frequent meaning at the longer SOA, while activation for the subordinate meaning increased. Results suggest that, while automatic processing occurs in both hemispheres, only the left hemisphere engages in controlled processing of ambiguous word meanings. In addition, the present results support the idea that the right hemisphere has a special role in ambiguity resolution and that the right hemisphere lexicon possesses a richer endowment than earlier thought.     

Naltrexone-reversible pain suppression in the isolated attacking mouse

Fighting pairs of isolated DBA/2 mice showed a significant increase in tail-flick response latencies independent of whether opponents were losing or winning the combat. The effect lasted less than 10 min in both animals. Elevated pain thresholds were also found in isolates that attacked a nonaggressive conspecific, and were prevented by naltrexone (0.2 mg/kg), while a larger dose (1.0 mg/kg) inhibited the attack behavior. A small increase in pain threshold was observed after exposure of isolates to the test box alone, while isolation per se had no effect on baseline tail-flick latencies. The data demonstrate that endogenous pain suppressing systems are activated during attack and suggest that this opioid-mediated antinociception is a correlate of the isolation syndrome, reflecting enhanced arousal of the attacking animal.     

An evaluation of the Garren-Edwards diet and behavior modification program

This study evaluated the efficacy of the Garren-Edwards Behavior Modification Program, which uses the Garren-Edwards Gastric Bubble as an adjunct to treatment. Group therapy sessions were conducted with 23 morbidly obese subjects for 6 months on a biweekly basis. Each therapy session used a five-stage problem-solving sequence designed to facilitate adaptive behavioral alternatives. In evaluating weight change, a multivariate analysis of variance was conducted along with two preplanned orthogonal comparisons. Patients lost significant amounts of weight between initial to 3-month (p<.0001) and 3- to 6-month intervals (p<0001). A similar treatment effect was noted in an additional sample of 24 morbidly obese subjects following 3 months of treatment (p<0005). The findings support the value of longer goal-oriented programs in promoting continued weight loss. Implications for treatment process and therapist interventions prompted by this new format are discussed.     

A developmental-genetic analysis of aggressive behavior in mice (Mus musculus): III. Behavioral mediation by heightened reactivity or immobility?

This research was designed to investigate development and behavioral mediation in lines of ICR mice that have been selectively bred for aggressive behavior. General behavioral reactivity and behavioral immobility have been implicated as potential mediators by prior analyses of preattack interactions. To evaluate the separate roles of these dispositions, the emergence of attacks in genetically selected lines was tracked for 11 years by three levels of analysis: over successive generations, over development, and over dyadic interactions. Convergent outcomes were observed in all three levels with respect to two findings: (a) Robust line differences were obtained in attack behaviors, and (b) strong associations were found between line differences in attacks and line differences in behavioral immobility. Conversely, all three levels of analysis indicated a weak and inconsistent association between line differences in attacks and measures of social and nonsocial reactivity.