Learning from parents' stories about what works in early intervention

Using a multiple case study approach, this ethnography examined the experiences of parents of children deemed at risk for developmental delays or disabilities who had received early intervention (EI) services (birth to age 3 years) in a large urban location in Western Canada. Participants (11 adult parents and 7 children) were drawn from six families. Methods of data collection included focus groups (FG), face‐to‐face interviews and file reviews. Member check and expert reviews were conducted throughout data collection and data analyses as part of the validation process in this ethnography. Qualitative content analyses followed by thematic analyses highlighted the implementation of family‐centred practices (FCP) as a main theme. Parents identified how EI professionals using FCP embraced collaborative practices. FCP resulted in parents leading the EI process for their children. More specifically, EI professionals shared strategies and information to support parents in gaining a deeper understanding of their children's individual developmental characteristics. Parents expressed how empowering this level of understanding was for them as they learned to articulate what were their children's needs for developmental, health and educational services. Recommendations for future research include inquiring about parents' experiences for families of diverse constellations and/or residing in smaller urban or rural communities.     

原发灶切除在转移性乳腺癌治疗中的地位

无论是国内还是世界其他国家,乳腺癌近年来已成为女性常患恶性肿瘤之首。早期乳腺癌通过手术、化疗、放疗及内分泌治疗等综合治疗后可以达到长期生存。然而对于晚期乳腺癌,特别是伴有远处转移的乳腺癌,疗效却不尽如人意。对于转移性乳腺癌,目前治疗优先选择毒性尽可能小的全身系统性治疗方案;而对于需要缓解症状或避免即将发生并发症（如皮肤溃疡、出血、真菌感染以及疼痛等）的情况可于全身治疗后行相应手术。然而对于转移性乳腺癌是否手术切除原发灶以及是否可从手术中获益,仍然充满争议。     

非小细胞肺癌 EG FR 基因突变检测与临床意义

采用荧光PCR法对199例晚期非小细胞肺癌（NSCLC ）组织进行表皮生长因子受体（EGFR ）基因突变检测,分析EGFR基因突变的分布特征及其与临床病理特征的相关性。结果显示56例（28．1％）存在EGFR基因突变,其中27例（13．6％）为外显子19突变,25例（12．6％）为外显子21突变,2例为外显子18突变,1例外显子20突变,1例外显子18和20的共突变。另外,除广东及安徽省铜陵市外,辽宁地区NSCLC患者EGFR基因突变率及主要突变类型与其他地区相符,常见于外显子19、21突变,其中腺癌、不吸烟患者突变率更高,更适宜EGFR-TKI靶向治疗。     

‘You have to treat the person,not the mouth only’: UK dentists’ perceptions of communication in patient consultations

Effective communication between patients and health professionals is a key component of patient-centred care. Although there is a large body of literature focusing on doctor-patient communication, there has been limited research related to dentist-patient communication, especially presented from the dentists’ perspective. The aim of our study was to explore UK dentists’ perceptions of communication in their consultations, and the factors they perceive may influence this. We conducted semi-structured interviews with eight dentists in UK dental NHS practices. Thematic analysis revealed three themes (‘Treating the whole person’, ‘Barriers to patient-centred communication’ and ‘Mutuality of communication’), which reflected the dentists’ perceptions of their own communication during consultations, the patients’ interaction skills, attitudes (and characteristics that may affect them), and external factors, such as time constraints, that can influence dentist-patients’ encounters. These in-depth accounts are valuable, in that we see what dentists perceive is important, obstructive and facilitative. They report using a patient-centred approach in their everyday dental practice; however this is often difficult due to factors such as time constraints. Although they emphasized that the patient has an active role to play in the communication process, it may be the case that they also need to play their part in facilitating this.     

卜弥格《医学的钥匙》探微

波兰籍传教士卜弥格（Michel Boym）是17世纪中医西传过程中的重要人物之一,其作品《医学的钥匙》引发了国内外学者的关注。旨在对这部著作的文章架构与基本内容作出分析并从中管窥卜弥格对中国医学身体知识的认识。其中,卜弥格个人的欧洲古典医学和哲学背景对中医知识的阐释发挥了相当大的作用。他对于中医知识体系内身体知识的解读可归结为三种类型：一是左右二分的身体;二是以圆为图式的身体;三是不断变化的身体。实际上,卜弥格的这三种身体观念是一套兼具中欧两种医学的特点,却又与二者都有差别的一种知识体系。

     

神经科学决定论与自由意志——兼论自由意志与自我是否可能?

神经科学的最新研究成果为决定论提供了科学依据,由此推断没有自由意志和恒定不变的自我。而传统生命伦理学中我们对其它生命体的伦理义务乃是基于这个生命体具备自由意志,即有自我的精神生活。神经科学技术对自由意志和自我的挑战不会对我们的伦理实践产生重要影响。只有在实践生活中人们采用了科学研究结论,从神经科学的发现到影响我们伦理实践的范式转换才会发生。从相容性与非相容性、物理系统自身的识别、神经科学的其它证据等方面探讨了怀疑的内在原因,认为不会因为神经科学家的新发现而否认自由意志和恒定自我。     

新型冠状病毒肺炎定点医院医护人员心理状况调查分析

为了解定点收治新型冠状病毒肺炎患者的医院中医护人员心理状况,从而针对性地进行心理护理,采用便利抽样法,应用《医护人员心理健康调查表》对3所定点收治新型冠状病毒肺炎患者的医院中1 266名医护人员进行问卷调查。结果显示,定点医院医护人员中,27.5%存在抑郁,26.3%存在焦虑,26.0%存在孤独。女性、已婚、传染科、发热门诊、监护室相比男性、未婚、普通门诊更容易抑郁;传染科、监护室相比普通门诊更容易焦虑。因此,医院应加强对这类群体的心理疏导和人文关怀,以减轻心理压力,提高工作效率。     

医学伦理学与生命伦理学关系类型辨析——基于国内外文献的考察

医学伦理学与生命伦理学的关系在逻辑上有包容论、互异论和交叉论（延续论）三种可能的类型。包容论认为,后者关注范围更广,前者作为一个部分包括在生命伦理学当中。互异论主张,两个概念在跨学科特点方面不同,生命伦理学必须通过跨学科协作,以公共性为导向,而医学伦理学较为单一,以职业性为目标。交叉论（延续论）强调,医学伦理学经历了古代医德学,近现代医学伦理学和生命伦理学。包容论与互异论过于强调二者的相同或区别,割裂了二者内在联系,片面性显而易见。交叉论（延续论）看到了二者内在逻辑,反映了本体属性,是更为合理的评价。