Results of neurophysiologic studies in ophthalmic migraine

The influence in 8 of our patients with ophthalmic migraine of photic driving with sine-like flashing lights on EEG background activity was checked and the visually evoked potentials following the application of diffused simple light stimuli were analyzed using the recovery cycle technique. The results indicate a slightly increased tonic activity of the structures of the mesencephalic formatio reticularis, such as may be produced by slight functional disturbances. Some vegetative secondary symptoms of migraine attacks and some of the changes in EEG observed in patients with ophthalmic migraine are explicable by such an abnormality.     

Behavior of visual evoked potentials (pattern reversal VECP) in smokers

Twenty six clinically healthy smokers were studied with transient pattern visual-evoked potentials. In comparison with a sample of "normal" subjects we found a difference of some parameters (P less than 0.05): the P2-latency and the interocular difference of latency on average were 6-7 ms respectively 2 ms larger. Thirteen subjects have had a prolonged P2-latency (P less than 0.05) and/or a difference in interocular latencies larger than 5 ms. These findings may suggest on subclinical disturbances of visual system and indicators of an special sensitivity of that person. The findings are possibly related to tobacco-alcohol amblyopia.     

Cue depreciation: when word fragment completion is undermined by prior exposure to lesser fragments

The ability to think of a previously studied item has often been shown to be impaired when, in one way or another, the extraitem context is changed from study to test. In a series of five experiments, such impairment is induced in a somewhat different way. A fragment (e.g. r-i--rop) of a just-studied word (raindrop) is shown to be less readily completed if it is presented bit by bit (r------p, r----r-p, r-i--r-p, r-i--rop) rather than all at once (Experiments 1, 3, 4, and 5). No such effect is found if the word has not been studied beforehand (Experiments 2, 3, 4, and 5). This pattern of results occurs even when fragments of studied and nonstudied words occur in the same test and under conditions in which subjects cannot tell whether a given fragment is of a studied or nonstudied word (Experiments 4 and 5). In addition, for words that have been studied beforehand, the impairment is shown to increase systematically with the number of steps involved in the presentation of the word fragment (Experiment 3) and also to persist when the time allowed for completion of the final version of the fragment is increased from 4 s to a full minute (Experiment 5).     

The experience of self-awareness and its relation to level of self-consciousness: An experiential sampling study

The present research studied self-awareness by utilizing experiential sampling methodology, which allows for the random sampling of individuals' thoughts and feelings as they go about their normal daily activities. Neither Study 1 nor 2 found a relation between private or public self-awareness and negative affect. However, attention to private self-aspects was generally more positive and less ruminative for low as opposed to high private self-conscious subjects, and awareness of oneself as a social object was generally more positive but less important for low as opposed to high public self-conscious subjects. What may have accounted for the negative relation between private self-consciousness and average affect was that low private self-conscious subjects were more likely to attend to their private self-aspects if they were pleasant than if they were unpleasant, while high private self-conscious subjects' degree of private self-awareness was unrelated to whether the content of this state was pleasant or not. These findings are consistent with the hypothesis that low private self-conscious individuals engage in a more selective type of self-attention when in the private self-aware state than do high private self-conscious individuals. Regarding the relation between self-awareness and social context, both studies found that the presence of others results in a heightened public self-awareness. However, even though subjects were more attentive to public self-aspects when with others than when alone, in general, they were more attentive to their “private self” than to their “public self”. Results are discussed in terms of current self-awareness theory.     

Catamnestic surveys on somato-psychosocial development in childhood and adolescence of patients with unipolar depressive and bipolar manic-depressive psychoses

The somatic and psychosocial development of 80 subjects with manifest affective-phasic psychoses is studied retrospectively and compared with that of an identically sized control group consisting of neuropsychiatrically healthy subjects. Statistically significant differences were found particularly in the answers to questions dealing with social situation and social adaptability. Achievement at school and vocational qualifications were lower among the parents of the patients than among those of the healthy subjects. Characteristic features of the patients' childhood and adolescence were transient depression, often for no apparent cause, and maladaption, and vocational wishes were fulfilled less often than among the controls. The patients experienced greater difficulty in settling in to a new group due to their contact difficulties.     

Acoustically evoked brain stem potential in Wilson disease

By 48 patients with Wilson's disease the brainstem acoustic evoked potentials were stated. There were 35 pathological findings (73%), 13 were normal (27%). The waves, determined by the middle and upper brainstem (Pons and Mesencephalon) showed most of all pathological changes. Those patients with forms of Wilson's disease called Pseudoskelerose and Pseudoparkinson showed the most pathological findings. But one could watch these findings by about 30% of patients in preclinical stage. This method can possibly be used for early detection of disorders of brainstem functions and in the same way it can be used for control of treatment by patients in preclinical stage.     

Mental health symptoms,well-being and experiences of the COVID-19 pandemic: A mixed-methods practice-based study

The COVID-19 pandemic necessitated abrupt and substantial changes in daily life, and public health strategies intended to protect physical health can negatively affect mental health and well-being, especially for individuals with pre-existing mental health challenges. For this study, we surveyed a sample of clients (N = 94) in the summer of 2020 from a community mental health clinic in the northeast United States. A mixed-methods, concurrent triangulation design was used to (a) identify client subgroups on indicators of mental health (i.e. anxious and depressive symptoms) and emotional, psychological, and social well-being using latent profile analysis (LPA), and (b) within these subgroups, examine qualitative, thematic patterns in self-described challenges, benefits and learning related to the pandemic. The LPA revealed five distinct subgroups with various levels of symptoms and well-being, including Stagnant (moderate symptoms/moderate well-being), Languishing (high symptoms/low well-being), Flourishing (low symptoms, high well-being), Fortitudinous (high symptoms, moderate well-being) and Mobilized (moderate symptoms, high well-being). These divergent subgroups support the need to conceptualise mental health symptoms apart from well-being and assess for heterogeneous constellations of such constructs among psychotherapy clients. Thematic analysis offered additional insight into pandemic experiences within each subgroup, including attention to psychological, emotional, behavioural/lifestyle, relational, physical and ecological/contextual dimensions of self-experience, as well as the ways clients had adjusted to the pandemic's circumstances. Findings support nuanced conceptualisations of positive mental health and offer insight into coping and adaptation during this public health crisis.     

The sociodemographic and psychosocial correlates of COVID-19 vaccine concerns among urban college students

COVID-19 vaccine concerns remain high among Americans. Although recent studies have investigated the sociodemographic disparities in vaccine concerns, less attention has been given to reasons for vaccine skepticism and psychosocial factors that may explain it. The current study examined specific types of vaccine concerns among a diverse sample of college students (N = 1985) living in New York City. Participants who identified as Black, younger, with later immigrant generational status, and those with more conservative political leanings reported more vaccine concerns. Concerns regarding vaccine side effects were the most frequently reported source of concern. Reason for getting vaccinated, personal experiences with COVID, and COVID stress was also associated with vaccine concerns. Study results emphasize the importance of sociodemographic factors and COVID knowledge and stress in examining and addressing vaccine concerns.     

A test of vaccine endorsement by political in- versus out-group sources: Effect on vaccination likelihood and exploration of mediation through perceived bias and liking

This study investigated whether political endorsements from in- versus out-group political elites would influence likelihood of COVID-19 vaccination. In March 2021, we ran an experiment with Democrats and Republicans in the United States to examine whether they would be more likely to get vaccinated following endorsements by former Presidents Obama or Trump. Participants reported greater likelihood of getting vaccinated if the vaccine was endorsed by an elite from their own rather than the opposing party. This effect was driven by Trump, who increased vaccination likelihood among Republicans but decreased it among Democrats. We also investigated the mechanisms underlying this persuasion effect and found that perceived bias and liking were plausible mediators, whereas perceived trustworthiness and expertise were not. This study highlights the potential of having endorsements from both Democrat and Republican political elites to increase support for health behaviors in a politically charged climate.     

Distress,wellbeing, and growth amidst COVID-19: Considering the dynamic interplay between positive and negative anticipatory emotions

Although negative anticipatory emotions are typically seen as risk factors for poorer psychological outcomes over COVID-19, emotion theorists suggest that this risk may be attenuated if balanced by the experience of positive emotion. Thus, the current study examined whether interactions between positive and negative anticipatory emotions were concurrently associated with psychological distress and greater personal wellbeing/posttraumatic growth (PTG) at three distinct periods (i.e., pre-lockdown, during lockdown, post-lockdown), and whether associations varied by these three COVID-19 time periods. The study utilizes two large longitudinal Australian samples, surveyed in 2020 prior to, during, and after a strict 4-month lockdown that occurred in Australia. Overall, positive emotions attenuated the adverse psychological outcomes arising from higher levels of negative emotion (i.e., higher psychological distress and lower personal wellbeing). Observed effects varied according to COVID-19 threat exposure. Specifically, the interaction was significantly associated with psychological distress prior to the lockdown for Sample 2, and during the lockdown for both samples. The interaction was significantly associated with wellbeing (Sample 2) prior to, and during, the lockdown but only marginally associated post-lockdown. The interaction, however, was not significantly associated with PTG (Sample 1). The results suggest that it is valuable for future research to consider greater emotional complexity (i.e., mixed emotions) over COVID-19, and other stressors more generally, to encompass a more nuanced understanding of resilience.