Diurnal Patterns of Unpleasant Mood: Associations with Neuroticism, Depression, and Anxiety

The literature on symptoms of depression has included diurnal changes in mood. The morning-worse pattern is commonly mentioned. This pattern is often associated with endogenous or vegetative symptoms (e.g., weight and appetite loss, loss of pleasure, psychomotor retardation). However, depression researchers have also identified an evening-worse pattern of mood. This pattern is sometimes thought to be associated with milder depressive symptoms, and may characterize chronic dysthymia rather than clinical depression. The present study examines a nonclinical sample to test the hypothesis that an evening-worse diurnal pattern of mood would be associated with trait neuroticism, anxiety, and subclinical depressive symptoms. An experience sampling methodology was employed to assess mood three times a day for 60 consecutive days. This allowed us to calculate a reliable aggregate score for diurnal mood patterns. The evening-worse pattern was associated with many neurotic features, with scores on depression and anxiety measures, and with a cognitive style indicative of hopelessness. Discussion focuses on how an evening-worse diurnal pattern of mood may be indicative of mild subclinical depression, chronic dysthymia, or personality traits associated with negative affectivity.     

Neurofibromatosis Type 1 in Genetic Counseling Practice: Recommendations of the National Society of Genetic Counselors

The objective of this document is to provide recommendations for the genetic counseling of patients and families undergoing evaluation for neurofibromatosis type 1 (NF1) or who have received a diagnosis of NF1. These recommendations are the opinions of a multi-center working group of genetic counselors with expertise in the care of individuals with NF1. These recommendations are based on the committee’s clinical experiences, a review of pertinent English language medical articles, and reports of expert committees. These recommendations are not intended to dictate an exclusive course of management, nor does the use of such recommendations guarantee a particular outcome. These recommendations do not displace a health care provider’s professional judgment based on the clinical circumstances of an individual patient. Both Heather B. Radtke and Courtney D. Sebold contributed equally to this document.     

The dynamics of empirically derived factors in the therapeutic relationship

The therapeutic relationship is the source of major concepts in psychoanalytic clinical theory. Such concepts as resistance, transference, countertransference, and the alliance are fundamental, even though there may be shifts in meaning between theoretical schools and clinical contexts. In the clinical psychoanalytic literature, disagreement exists over the nature of the alliance and its essential components. Empirical studies using reliable patient, therapist, and observer scales to assess the alliance demonstrate a correlation with psychotherapeutic gains. In the study reported here, thirteen patients were followed for 6 to 33 months of psychodynamic psychotherapy, during which time their views of the therapeutic relationship were assessed, and several experiential measures taken, all on a weekly basis. Statistical analyses reveal that the therapeutic relationship, as reflected in the patients' weekly responses to the St. Louis Therapeutic Relationship Rating Scale, has four distinct components: therapeutic alliance, resistance, transference love, and negative transference. On a week-by-week basis, the therapeutic alliance was the strongest predictor of improvement in patient-reported general adjustment, as reflected in such areas as self-esteem, positive affect, social relations, work productivity, satisfaction, and optimism. Time plots of the variables show the typical time course for the components of the therapeutic relationship, as well as for improvement on the experiential variables. Results indicate that the therapeutic alliance, transference, and resistance are central components of the psychotherapeutic relationship, which in turn predict the ongoing life experience of the patient.     

EVALUATIONS OF SEXY WOMEN IN LOW- AND HIGH-STATUS JOBS

We hypothesized that women who dress in a sexy versus business-like manner evoke negative emotions and perceptions of lesser competence if employed in high- (but not low-) status jobs. Male and female undergraduates evaluated a videotaped female target whose physical attractiveness was held constant, but who was (a) dressed in sexy or business-like attire and (b) allegedly either a manager or a receptionist. Participants exhibited more negative affect toward the sexily attired manager and rated her as less competent than the neutrally attired manager. This effect was fully mediated by emotional reactions. In contrast, the appearance manipulation had no effect on emotions toward or competence ratings of the receptionist. These findings suggest that a sexy self-presentation harms women in high-, but not low-, status jobs.     

The connection between social cohesion and personality: A multilevel study in the Kyrgyz Republic

As the discourse around societal cohesion grows and policy makers increasingly turn their attention towards improving cohesion, understanding its role for the lives of individuals becomes ever more important. Our study examines whether the social cohesion of the immediate living context is related to the strength of Big Five personality traits among individuals. Using data from a community survey of 6252 adults living in 30 rural sub-districts in the Kyrgyz Republic, where social cohesion is a sizable policy concern, we conduct a multilevel analysis of the relationship between sub-district cohesion and individual personality. Results indicate that higher levels of cohesion are significantly related to higher individual levels of agreeableness, conscientiousness and openness. However, no relationship is found with extraversion or neuroticism. Thus, where a social entity has higher cohesion, this entity will also have inhabitants with a greater prosocial and communal orientation towards others, greater conscientiousness and more openness to experience. These findings imply that social cohesion may be one geographical social indicator related to variation in personality traits. Moreover, the findings suggest that understanding social cohesion requires both macro- and micro-perspectives and that its connection to these particular personality traits should be taken into consideration.     

Male HIV-1 transgenic rats show reduced cocaine-maintained lever-pressing compared to F344 wildtype rats despite similar baseline locomotion

The HIV-1 transgenic (Tg) rat model is valuable for understanding HIV-associated neurocognitive disorders (HAND) and accompanying substance use and misuse. Tg and F344/NHsd wildtype (WT) rats were allowed to self-administer intrajugular cocaine. For the first 7 sessions, neither genotype self-administered cocaine (0.1 mg/kg/infusion) on a fixed ratio 1 schedule. We thus implemented a lever–cocaine “autoshaping” session followed by a series of manipulations changing dose and reinforcement schedule. Tg rats self-administered much less cocaine than WT rats throughout the study. Of 8 Tg rats, 5 modestly increased self-administration from sessions 36–50. Of those, only 3 showed a lever discrimination. Of 10 WT rats, 8 acquired robust self-administration by session 19; all WT rats self-administered cocaine by the end of the study. WT and Tg rats had similar baseline locomotor activity in the self-administration chamber suggesting that the low levels of cocaine intake in the Tg rats did not reflect a nonspecific motor impairment in this rat strain. Concomitant measurement of activity with self-administration revealed activity increases that followed increased cocaine intake. That relation held in Tg rats. Therefore, the present study provides evidence that HIV-1 Tg rats are less sensitive to the reinforcing effects of cocaine than their F344 WT counterparts.