Extracellular guanine-based purines, mainly the nucleoside guanosine, have recently been shown to exert neuroprotective effects, which seem to be related to antagonism of the glutamatergic system. In this study, we investigated the effects of acute oral administration of guanosine on inhibitory avoidance task in rats and mice. We also studied its effects on locomotor activity, anxiety-related behaviors and mechanisms of action involving the purinergic system. Guanosine (2.0 and 7.5mg/kg, per os), administered 75min pretraining, dose-dependently impaired retention of the inhibitory avoidance task in rats and mice, an effect not prevented by the adenosine receptor antagonist caffeine. Guanosine presented no effects on locomotor activity and anxiety-related behaviors. This amnesic effect of guanosine may be compatible with inhibition of glutamatergic system and seems to be not mediated by adenosine. 相似文献
Although men and women help others, there are systematic gender differences in the type of helping they perform. Consistent with traditional gender roles and stereotypes, men typically help in agentic ways, and women typically help in communal ways. Drawing on the Theory of Planned Behavior, the Gender Roles Inhibiting Prosociality model predicts that gender stereotypes about gender-inconsistent helping create negative attitudes, restrictive subjective norms, and low self-efficacy that undermine helping intentions, which, in turn, reduce engagement in gender-inconsistent helping contexts. Across three studies (N?=?1,355), we find empirical support for the hypothesized model: When asked to imagine engaging in a gender-inconsistent (vs. gender-consistent) helping scenario, participants anticipated feeling worse, expected others to judge them more negatively, and reported decreased self-efficacy beliefs, and these factors predicted lower intentions to engage in gender-inconsistent helping. Critically, behavioral intentions explained some of the variance in gender-inconsistent helping during the following month. Internal meta-analyses of the differences between gender-consistent and -inconsistent helping on attitudes, subjective norms, self-efficacy, and behavioral intentions across studies revealed small-to-medium average effect sizes (ds?=?0.16—0.47). These results have the potential to inform interventions aimed at increasing helping in all its forms.
How do people cope with stress? Research suggests that people have a number of strategies, including turning to the groups to which they belong, increasing feelings of identification and affiliation. We examine a novel extension of this strategy: adopting visible reminders of one's group identity. In two experiments (Ns = 103 and 194), we explore whether students are more likely to use an artifact that displays their university identity in situations of high, compared to low, evaluative stress. In Experiment 1, students were more likely to choose a university‐branded pen (vs. an identical unbranded pen) to complete exam questions when their performance would be evaluated versus not. In Experiment 2, we found the tendency to use a university‐branded pen in the face of evaluative stress emerged only among people who found the evaluation personally relevant. In addition, we present converging results from two observational studies suggesting that students are more likely to wear clothing that signals their university identity on exam days compared to control days. These findings suggest that people may turn to visible reminders of group membership when facing evaluative stress. Although we found no consistent evidence for a psychological mechanism underlying this effect, we speculate about theoretically relevant possibilities. 相似文献
A major public health crisis facing America’s society is the increase in child and youth obesity, which has seen a fourfold
increase in the last four decades. Major concerns include what children eat for school lunch and what other foods are available
in schools. This paper illustrates efforts towards systems change in the luncheon program and food vending machines in the
Chicago Public Schools. We discuss the different factors that lead to such changes using the framework of the social ecological
model and the soft systems methodology, and we analyze how the resulting innovation was implemented and evaluated. First,
we present a theoretical perspective to explain factors that influence children’s eating patterns from a systems approach.
Second, we discuss the antecedent factors that lead to systems change. Finally, we examine challenges to systems change, such
as resistance to change, different stakeholder priorities, lack of resources, institutional bureaucracy, and unrealistic funder
expectations. 相似文献
This study investigated the relationship of identity development, measured by the Self-Identity Inventory (SII), universal-diverse orientation (UDO), measured by the Miville-Guzman Universality-Diversity Scale- Short (M-GUDS-S), to counsellor preference in a sample of 365 university students. After controlling for personal identity demographic variables, multiple regression analysis indicated SII and UDO accounted for significant additional variance in counsellor preference with Immersion (SII Scale 3), Relativistic Appreciation (MGUDS-S Subscale 2) and Comfort with Differences (MGUDS-S Subscale 3), identified as significant unique predictors. A canonical correlation analysis performed with 11 individual counsellor preference variables as criterion variables and 9 identity salience variables as predictor variables to explore the relationships between identity salience and counsellor preference yielded three significant canonical functions. 相似文献
Prostate carcinoma (PC) is the most commonly diagnosed cancer in men. Treatments for localized PC are associated with side effects including sexual dysfunction, which has been linked to decrements in health-related quality of life and elevated distress levels. In this study, we examined the relationship between 2 personality traits, interpersonal sensitivity and lack of sociability, assessed by the Inventory of Interpersonal Problems (IIP; Pilkonis, Kim, Proietti, & Barkham, 1996) and recovery of sexual functioning in 121 men (M age = 60.6 years) recently treated with radical prostatectomy. Interpersonal sensitivity refers to the predisposition to perceive and elicit criticism and rejection from others; lack of sociability refers to chronic difficulties taking the initiative in interpersonal situations. After adjusting for relevant covariates, interpersonal sensitivity, but not sociability, was significantly associated with lower levels of sexual functioning. Patient-physician communication and partner perceived social support were explored as mediators of this relationship. Although interpersonal sensitivity was significantly associated with both poorer patient-physician communication and lower levels of partner support, the results did not support mediation. This study provides preliminary evidence that certain IIP-assessed interpersonal styles may complicate the recovery of sexual functioning after surgical treatment for PC. 相似文献
This study integrated research on aggression, peer status, and social and academic functioning across the middle- and high-school transitions. We examined how peer status and aggression are related to adolescents' expectations about their academic and social functioning in a new school system before the transition into that system, and their perceived academic and social functioning after the transition. Social preference, perceived popularity, overt and relational aggression, and social and academic expectations were assessed in Grades 5 and 8; identical peer status and aggression constructs and perceived social and academic functioning were assessed in Grades 6 and 9. Results indicated moderate correlations between adolescents' social and academic expectations and perceived functioning across both school transitions. Girls reported higher social and academic functioning than boys did in most cases. Perceived popularity was consistently positively associated with academic and social expectations for middle and high school, whereas social preference was associated with perceived social functioning in both middle school and high school. The link between aggression and outcome variables varied by age and was moderated by gender and peer status. 相似文献
This article proposes four revolutions in psychotherapy. The first revolution invites therapists to focus on building client’s
strengths rather than patching up weaknesses. The second revolution proposes a technique of translating symptoms into gifts.
The third revolution invites therapists to consider alternative goals of psychotherapy other than returning the client to
previous levels of functioning. Finally, the fourth revolution challenges the dictum of psychotherapy training that therapists
should only teach their clients how to fish, metaphorically speaking, rather than giving them fish. Case studies are offered
focusing particularly on clients diagnosed with Major Depression and Attention Deficit/Hyperactivity Disorder. 相似文献
Sex Roles - Objectification theory suggests that sexualization has significant dehumanizing consequences for how perceivers see women. To date, research has mostly documented how sexualized bodies... 相似文献