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Mickaël Laisney Laetitia Bon Catherine Guiziou Nathalie Daluzeau Francis Eustache Béatrice Desgranges 《Journal of Neuropsychology》2013,7(1):107-120
Theory of Mind (ToM) allows one's own and others' cognitive and emotional mental states to be inferred. Although many patients with Alzheimer's disease (AD) display impaired social functioning as their disease progresses, very few studies have investigated ToM in AD. Those that have done so suggest that patients' ToM deficits are the consequence of other cognitive impairments. The aim of this study was thus to investigate changes in both the cognitive and the affective dimensions of ToM in AD, using tasks designed to circumvent the patients' comprehension difficulties. Sixteen mild to moderate AD patients and 15 healthy controls matched on age, sex and education level underwent cognitive (preference judgment and first‐ and second‐order false belief) and affective (Reading the Mind in the Eyes) ToM assessments. Comprehension of false belief stories was verified and an additional neuropsychological examination was undergone. We observed impaired performances by AD patients on all the ToM tasks. While working memory and executive functioning impairments contributed to the deterioration in the more complex aspects of cognitive ToM abilities as highlighted by a correlation analysis, we failed to observe any comprehension difficulties in patients who performed poorly on simple cognitive ToM tasks, which suggests that AD truly affects cognitive ToM. 相似文献
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Geometry, e.g., the shape of the environment, can be used by numerous animal species to orientate, but data concerning the mouse are lacking. We addressed the question of whether mice are capable of using geometry for navigating. To test whether aging could affect searching strategies, we compared adult (3- to 5-mo old) and aged (20- to 21-mo old) C57BL/6 male mice. We established a water maze task in which spatial information is provided by one landmark proximal to the target (featural information) and by the rectangular shape of the maze (geometric information). By means of probe trials in which we manipulated the presence of these two kinds of information, we show that adult mice can use both geometry and landmark to orientate. By contrast, aged mice do not use geometry and rely exclusively on the landmark to locate the platform. This study provides the first evidence that mice are capable of using geometric information for orientation and that this ability declines in aged animals. 相似文献
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《易传》作者有意表明了对《易经》的研究与评价的立场 ,《易传》文本包含有关美学—文学思想的内容。在前人研究的基础上 ,本文拾遗补阙 ,论述《易传》之“美”有美在自然、自然美高于艺术美、美乃自然而然、无所为而为等方面的内容以及阴柔之为美及其含蓄的特征 ;又 ,关于“修辞立其诚”的意义及其影响 ,关于“衰世之意”、“忧患”著书的意义及其对司马迁“发愤著书”说的影响等等。论述结合了与古今中外美学—文学理论的比较 ,加强证明了《易传》实为《文心雕龙》之先导 ,是我国最早作专书批评的文章—文学理论著作。 相似文献
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卫生保健政策与医学伦理学 总被引:1,自引:0,他引:1
杜治政 《医学与哲学(人文社会医学版)》1999,20(8):1-4
卫生保健政策是卫生资源、价值目标和伦理原则三者的结合。医学伦理学是卫生政策的重要基础。当代卫生事业的特点,卫生保健服务面临的挑战以及医学伦理主体与客体的变化,决定了医学伦理学在当代卫生保健政策中的特殊意义。在医学面临全民保健的阶段,一个科学的符合人民健康利益的卫生保健政策是不言而喻的。摆脱当前卫生政策面临的困难,要求必须在医学伦理学方面作出正确的选择。 相似文献
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G E Kühne H J Du Chesne J U Grünes D Krell R Pelliccioni 《Psychiatrie, Neurologie, und medizinische Psychologie》1978,30(9):513-521
The present study is intended to discuss use of video tape technics in psychiatric research in reference to method, engineering and clinical investigation. A self created variant of a clinical television system is debated. With the support of video tape methods will be realize improvements in quality of psychiatric investigation in view of procedure and determination of the results as well as reliability, objectiveness and exactitude in connection with a postgraduate continued professional training. Reconsiderations of psychiatric documentation systems with regard to reliability represent an other important field of employment. 相似文献
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Targeted digital advertising (TDA) is immensely popular among marketing practitioners; investigating its effects is increasingly becoming a subject of academic research. Brands can push advertisements of the same product from different sources to consumers in a targeted manner; however, the differences in the impact on consumers of TDA with different content sources are surprisingly understudied. Therefore, this study analyzes the consumers' purchase intentions in the context of TDA with different content sources (stars vs. bloggers vs. top e-commerce streamers), and the perceived differences between consumers with different thinking styles. Through two experimental studies, this study finds that TDA with top e-commerce streamers' recommendation source can better improve consumers' purchase intentions more than TDA with a star endorsement and TDA with a blogger evaluation. For consumers who prefer the rational thinking style, TDA with a star endorsement and TDA with top e-commerce streamers recommendation can be better; For consumers who prefer the empirical thinking style, TDA recommended by bloggers and TDA with top e-commerce streamers recommendation can be better. Furthermore, this study finds that consumers' mental simulation and perceived usefulness can mediate the relationships described above, and that the two play a chain mediation role. The findings contribute to the precision marketing literature by enriching the understanding of the psychological mechanism underlying consumers' perceptions of and decision factors toward the TDA. 相似文献
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中国古代关于认识真理性检验标准的思想可以大致归纳为四种主要观点。先秦及汉代的唯物主义思想家已经有了把感觉经验和行为效果作为检验认识真理性标准的思想;古代唯心主义思想家则坚持无客观标准论,他们要么直接坚持主观标准论,要么认为根本无是非标准可言;宋、明、清时期的一些唯物主义哲学家提出并坚持以客观事物或事实作为检验认识真理性的标准;与此不同,王廷相、王夫之、颜元等人则提出“行”标准说,这种颇具光辉的哲学思想,使中国古代关于认识真理性检验标准思想的探讨大大前进了一步。 相似文献