A second type of magnitude effect: Reinforcer magnitude differentiates delay discounting between substance users and controls

Basic research on delay discounting, examining preference for smaller–sooner or larger–later reinforcers, has demonstrated a variety of findings of considerable generality. One of these, the magnitude effect, is the observation that individuals tend to exhibit greater preference for the immediate with smaller magnitude reinforcers. Delay discounting has also proved to be a useful marker of addiction, as demonstrated by the highly replicated finding of greater discounting rates in substance users compared to controls. However, some research on delay discounting rates in substance users, particularly research examining discounting of small‐magnitude reinforcers, has not found significant differences compared to controls. Here, we hypothesize that the magnitude effect could produce ceiling effects at small magnitudes, thus obscuring differences in delay discounting between groups. We examined differences in discounting between high‐risk substance users and controls over a broad range of magnitudes of monetary amounts ($0.10, $1.00, $10.00, $100.00, and $1000.00) in 116 Amazon Mechanical Turk workers. We found no significant differences in discounting rates between users and controls at the smallest reinforcer magnitudes ($0.10 and $1.00) and further found that differences became more pronounced as magnitudes increased. These results provide an understanding of a second form of the magnitude effect: That is, differences in discounting between populations can become more evident as a function of reinforcer magnitude.     

Body‐Weight Self‐Schema: Determinant of Mood and Behavior in Women With an Eating Disorder1

The schema approach to self‐concept was used to investigate the association between body‐weight self‐conception and self‐esteem, negative affect states, and disordered eating behavior in women with anorexia nervosa (n= 26) or bulimia nervosa (N= 53) using experience sampling methodology. We predicted that self‐esteem would be lower and unpleasant affect and disordered eating behaviors would be higher when the body‐weight self‐schema was activated in working memory compared to when non‐weight‐related self‐schemas were activated. Participants recorded the currently activated self‐schema, self‐esteem, affect, and behavior in response to an alarm‐watch signal 5 times daily for 5 days. Activation of the body‐weight self‐schema was associated with lower self‐esteem and higher negative affect, but not higher levels of disordered eating behavior. Low self‐esteem and negative affect, however, were associated with disordered eating behavior. Findings have important implications for treatment of eating disorders.     

AN INQUIRY INTO THE ORIGINS OF LIFE ON EARTH— A SYNTHESIS OF PROCESS THOUGHT IN SCIENCE AND THEOLOGY

An initiating event in the development of life on earth is thought to have been the generation of self‐replicating catalytic molecules (SRCMs). Despite decades of work to reveal how SRCMs could have formed, a chemically detailed hypothesis remains elusive. I maintain that this is due, in part, to a failure of metaphysics and question this research program's ontologic foundation of materialism. In this essay I suggest another worldview that may provide more adequate ontologic underpinnings: Whitehead's process philosophy of dynamic, relational becoming. Here we come to see molecules not as unchanging objects but rather as processes that possess the capacity for subjective experience. Molecular transformation is driven by experience, both internal and external. Process thought accounts for the world's creative impulse by positing a God who lures the becoming of all entities toward greater complexity and value. Chemical evolution is now seen as divine motivation of molecular becoming and, as such, possesses the potential for introducing true novelty into the world. The “causal joint” between God and world is hypothesized to be an energy transduction at the molecular level that allows divine action without violation of chemical principles or physical laws.     

Feasibility of a Telephone Intervention for HIV Patients and Their Informal Caregivers

Objectives: To assess the feasibility of a telephone intervention for HIV-positive patients and their caregivers. Methods: HIV-positive participants, some co-enrolled with their informal caregiver, enrolled in this randomized study. Intervention-arm participants (124 patients and 76 caregivers; dyads assigned to same arm) received up to 12 scheduled calls from an interventionist over 6 months. Results: An average of 7.6 (SD = 3.0) calls to each participant was completed; 66.5% received at least 6 calls; 43.0% received more than 75% of the intervention (defined as ‘study adherent’). Having a higher T-cell count was associated with call adherence (p = .014); cocaine use was associated with reduced call adherence for both patients (p = .019) and caregivers (p = .083). Common telephone themes included problems with mood, relationships, finances, housing, and work; interventions (e.g., referral for mental health care) were initiated in response to these. Participant satisfaction was high, and many reported benefits from the intervention. Conclusions: Using a telephone intervention with HIV-positive patients and their caregivers is a feasible and potentially beneficial intervention.     

Exploring the Relation Between Memory, Gestural Communication, and the Emergence of Language in Infancy: A Longitudinal Study

The relationship between recall memory, visual recognition memory, social communication, and the emergence of language skills was measured in a longitudinal study. Thirty typically developing Swedish children were tested at 6, 9 and 14 months. The result showed that, in combination, visual recognition memory at 6 months, deferred imitation at 9 months and turn-taking skills at 14 months could explain 41% of the variance in the infants' production of communicative gestures as measured by a Swedish variant of the MacArthur Communicative Development Inventories (CDI). In this statistical model, deferred imitation stood out as the strongest predictor.     

Evaluating the validity of Myers‐Briggs Type Indicator theory: A teaching tool and window into intuitive psychology

Despite its immense popularity and impressive longevity, the Myers‐Briggs Type Indicator (MBTI) has existed in a parallel universe to social and personality psychology. Here, we seek to increase academic awareness of this incredibly popular idea and provide a novel teaching reference for its conceptual flaws. We focus on examining the validity of the Jungian‐based theory behind MBTI that specifies that people have a “true type” delineated across four dichotomies. We find that the MBTI theory falters on rigorous theoretical criteria in that it lacks agreement with known facts and data, lacks testability, and possesses internal contradictions. We further discuss what MBTI's continued popularity says about how the general public might evaluate scientific theories.     

Maternal separation exaggerates the toxic effects of 6-hydroxydopamine in rats: implications for neurodegenerative disorders

Many studies have shown that early life stress may lead to impaired brain development, and may be a risk factor for developing psychiatric pathologies such as depression. However, few studies have investigated the impact that early life stress might have on the onset and development of neurodegenerative disorders, such as Parkinson's disease, which is characterized in part by the degeneration of dopaminergic neurons in the nigrostriatal pathway. The present study subjected rat pups to a maternal separation paradigm that has been shown to model adverse early life events, and investigated the effects that it has on motor deficits induced by a unilateral, intrastriatal injection of 6-hydroxydopamine (12 microg/4 microl). The female rats were assessed for behavioral changes at 28 days post-lesion with a battery of tests that are sensitive to the degree of dopamine loss. The results showed that rats that had been subjected to maternal separation display significantly impaired performance in the vibrissae and single-limb akinesia test when compared to normally reared animals. In addition, there was a significant increase in the loss of tyrosine hydroxylase staining in maternally separated rats. Our results therefore suggest that adverse experiences sustained during early life contribute to making dopamine neurons more susceptible to subsequent insults occurring during more mature stages of life and may therefore play a role in the etiopathogenesis of Parkinson's disease.     

Depression, anhedonia, and psychomotor symptoms: the role of dopaminergic neurocircuitry

The heterogeneity of major depression suggests that multiple neurocircuits and neurochemicals are involved in its pathogenesis. Anhedonia and psychomotor symptoms are, however, particularly characteristic features of major depression and may provide insights into its underlying psychobiology. Importantly, these symptoms appear to be mediated by dopaminergic mesolimbic and mesostriatal projections, the function of which is, in turn, influenced by key gene variants and environment stressors. Indeed, there is growing evidence of the way in which the dopaminergic system is associated with cognitive-affective disturbances in depression, and provides a useful target for therapeutic interventions. At the same time, a range of other systems are likely to contribute to the psychobiology of this condition.     

'Divinity expresses the self ...' An investigation.

The self is more than conscious identity and location (i.e., the ego) because it includes and expresses the full range of the psyche, all conscious and unconscious elements included, and it is responsible for the unity of the psyche as a whole. Beyond this, the self concept sets up the basis for the linkage between analytical psychology and religious doctrines of transcendence. It has been stated by critics and sympathizers that Jung was a 'mystic', or a throwback to pre-Enlightenment medievalism, who equated the self with God, mixed up categories of transcendence and immanence, and put the psyche on a symbolic par with Divinity. While this does contain a kernel of truth about his late views, it is not quite as straightforward as it sounds. This essay(1) explores the complex relation of the self to the transcendent (Divinity), as Jung understood these terms and employed them, focusing especially on a critical passage from his last major work, Mysterium Coniunctionis. The notion of self as imago Dei grasps the paradoxical nature of the self, a coincidentia oppositorum that is at once personal and impersonal, embodying a pattern of Divinity that also is revealed as a coincidentia oppositorum, immanent and transcendent. Jung posits, moreover, a dynamic interactive relation between the self and the transcendence it mirrors. Altogether, this combination of features regarding the self sets Jung's psychology apart from humanistic and personalistic psychologies and secular depth psychologies such as those descended from Freud on the one side, and on the other side it also separates it from pre-Enlightenment dogmatic psychologies such as those belonging to religious fundamentalisms. This essay attempts to explore and to explicate the subtle space between purely secular and religious doctrines and to make the case that Jung's depth psychology represents a post-Enlightenment, post-secular, post-humanistic vision of the human as a material/spiritual being whose psyche links earth and heaven, the here and the beyond, the finite and the infinite. It is a radical attempt to break out of modernity without regressing to medievalism.