先天视觉经验缺失对颜色认知的影响：一项ERP研究

感觉与认知是否是相互独立的？本研究通过对比先天盲被试与明眼被试在进行物体颜色判断时的行为反应和神经电生理信号变化,探讨视觉经验缺失对颜色认知的影响。结果发现,先天盲被试具有一定的颜色知识,但其水平低于明眼被试;两组被试都出现了由颜色不匹配所诱发的N400效应,且都表现出左半球优势;但是盲人组的N400效应大于明眼组,盲人组的N400反应潜伏期小于明眼组。该结果说明,直接的视觉经验是颜色认知的充分条件而非必要条件。     

项目竞争强度对网络成瘾大学生提取诱发遗忘的影响

执行功能缺陷是网络成瘾发生、维持和复发的原因之一,以往研究侧重于探讨网络成瘾者注意控制、反应抑制等执行功能成分的损伤状况,而其记忆抑制状况尚不清楚。本研究通过考察网络成瘾大学生的提取诱发遗忘（RIF）来探讨其记忆抑制的特点及RIF的产生机制。结果发现：低网络成瘾个体在高项目竞争强度下表现出显著的RIF,在低项目竞争强度下未产生;高网络成瘾个体在低项目竞争强度下表现出显著的RIF,在高项目竞争强度下未产生。结果表明网络成瘾大学生的记忆抑制能力受损严重,其在低项目竞争强度下易受相关代价与效益问题（CCB）影响而产生干扰性RIF。     

Resting Heart Rate,Vagal Tone,and Reactive and Proactive Aggression in Chinese Children

Abundant research conducted in Western contexts has shown that biological risk factors such as low resting heart rate (HR) might be related to childhood aggression. However, it was unclear (1) how resting HR, as well as other markers of cardiac functions such as resting vagal tone, may be related to subtypes of aggression such as reactive and proactive aggression, and (2) whether the HR-aggression relation can be replicated in non-Western contexts. Therefore, this study examined the concurrent and prospective relations between resting HR, vagal tone, and Chinese children’s reactive and proactive aggression. Participants were 183 children (M age?=?7.64 years, 91 girls) recruited from an elementary school in Zhenjiang, PRC. Children’s resting HR and vagal tone were assessed in the second grade (T1). Teachers rated children’s reactive and proactive aggression in the second (T1) and fourth grade (T2). Results showed that lower resting HR at T1 was associated with higher reactive and proactive aggression at T1 and T2, and higher vagal tone was associated with lower HR, which in turn was related to higher reactive and proactive aggression at T1 and T2. Lower vagal tone was directly related to higher reactive but not proactive aggression at T1 and T2, whereas lower HR was related to higher reactive aggression at T2 for children with low or moderate vagal tone but was not for children with high vagal tone. These psychophysiological findings from a non-Western context add additional support for both similarities and differences between reactive and proactive aggression in childhood.     

组织型插图对不同认知方式个体说明性文本阅读的影响

采用图文相继呈现、文本逐句阅读的范式,通过反应时技术与出声思维的方法考察了组织型插图对不同认知方式个体说明性文本阅读过程与阅读结果的影响,结果发现,与单一文本相比,场独立个体在有插图条件下的阅读成绩显著提高,而阅读时间没有增加,并产生了更多的推理、细化和提问策略;而场依存个体在有插图条件下的阅读成绩显著提高,阅读时间也显著增多,而理解策略没有变化。这说明组织型插图对两种认知方式个体说明性文本的阅读均起到促进作用,但场独立个体没有因为增加组织型插图而付出更多的加工努力,而是通过调整理解策略的方式来提高阅读效果;而场依存个体在阅读过程中没有根据组织型插图调整理解策略,阅读效果的提高是以付出更多的加工努力为代价的。     

Shyness and Psychosocial Functioning in South Korean Children

The purpose of this study was to examine whether anxious shyness and regulated shyness, initially identified in the Chinese culture, is found in South Korean children, and to explore whether these two forms of shyness were differentially related to children's psychosocial functioning. Participants were 544 fourth to sixth grade children (251 girls, M age = 11.38 years old) who were recruited from an elementary school in Bucheon City, South Korea. Children's anxious and regulated shyness were measured using peers' nominations and teachers' ratings, whereas their social preference and social impact were assessed using peers' nominations. Parents rated their children's temperamental shyness and effortful control, and children self‐reported their loneliness and interpersonal concerns. The results of confirmatory factor analysis replicated the two factor model of shyness found in previous studies of Chinese children. Anxious shyness and regulated shyness were positively associated and were similarly related to temperamental shyness. Anxious shyness was negatively related to effortful control and social preference, and positively associated with self‐reported loneliness and interpersonal concerns, whereas regulated shyness was positively related to effortful control and social preference and negatively associated with loneliness and social impact. These results were generally consistent with prior Chinese findings and provided preliminary support for the construct validity of anxious and regulated shyness in another Asian culture that emphasizes interdependence and modesty. Copyright © 2013 John Wiley & Sons, Ltd.     

妊娠晚期亚临床甲状腺功能减退症对母婴合并症的影响

本研究旨在观察妊娠晚期亚临床甲状腺功能减退症对母婴合并症的影响。最终选择2010年1月～2010年11月期间共325例妊娠晚期孕妇分为病例组（A组,n＝65）和正常对照组（B组,n＝260）,观察两组之间母婴合并症的变化。结果显示,两组之间在年龄、住院日、血压、体质量指数（BM I）、心率、分娩时孕周、血糖以及血脂方面差异均无统计学意义（P＞0．05）。但与B组相比较,A组发生母亲合并症及胎儿合并症的发生率明显增加,差异有统计学意义（P＜0．05）。此研究提示妊娠晚期亚临床甲状腺功能减退症增加母婴合并症的风险。     

微流控分析芯片在循环肿瘤细胞检测中的运用

随着人们对于肿瘤性疾病的发生、发展、转移机制的进一步探索,循环肿瘤细胞（CTCs）逐渐进入人们视野,其应用价值日益体现,可用于肿瘤性疾病的早期诊断及治疗效果的监测,尤其是对于早期肿瘤的诊断具有独特优势。其富集技术及检测方法也在发生着日新月异的变化。近年来,微流控分析芯片技术运用于 CTCs 的富集及检测,具有高丰度、高富集度、高活性及不需要对样本进行预处理等优点使得人们聚焦于此技术,本文对微流控分析芯片在 CTCs 检测中的运用做简要综述。     

广西肝恶性肿瘤患者住院费用的研究

为探讨肝恶性肿瘤患者住院总费用情况,对广西2010年～2012年间肝恶性肿瘤患者的住院费用资料进行统计学分析,比较肝恶性肿瘤患者3年住院总费用的变化情况,并采用多重线性回归分析方法,分析肝恶性肿瘤患者住院总费用的影响因素.结果显示广西肝恶性肿瘤住院患者逐年增多,住院费用逐年增高;住院天数、有无手术、有无合并症、有无院内感染、性别、年龄6个因素是住院总费用的影响因素.我们应加大预防控制肝恶性肿瘤的力度,建立单病种诊疗规范和费用控制标准,推进临床路径管理,以减轻患者的经济负担.     

脉理的阴阳和谐观研究--以《濒湖脉学》“缓脉”为中心论证

在《濒湖脉学》的脉理中,把无病的缓脉认为是有神、有胃气的平脉,无病的缓脉是脾胃这一人体后天之本正常运化的脉象。脾脉为缓脉,其余四脏脉以及四季脉也要兼有缓脉,才是阴阳和谐的脉象,脾脉拥有阴阳和谐的缓脉能为其余各脏腑提供精气,从而保证各脏腑的正常运化,只有各脏腑的正常运化才能维护人身体的阴阳和谐。当人身体的阴阳失去和谐出现病变的时候,脉象就会表现为太过或不及或各脏脉俱缓,少有或失去了缓和的脉象以及各脏脉均失去个性的病缓脉。     

直肠间质瘤致下消化道大出血1例报告

胃肠道间质瘤是一种发生于消化道的少见的间叶肿瘤,直肠间质瘤更为罕见,在直肠肿瘤中的发生率0．1％以下。直肠问质瘤的临床表现无特异性,与其他直肠肿瘤相似,随肿瘤逐渐增大可表现为排便习惯改变、便血、排便困难等。临床确定诊断困难。手术治疗是能够治愈直肠问质瘤的唯一方法。格列卫作为一线化疗药物对术前降期及改善预后都有良好疗效。本例患者因下消化道大出血入院,肿瘤近肛缘,术中病理考虑为直肠闻质瘤,完整切除肿瘤后行保肛术。术后应用格列卫,随诊3个月无复发、转移。