基于利益相关者角度分析居民健康档案存在的问题及对策

居民健康档案对政府、卫生机构、居民都具有重要意义.健康档案工作开展时间不长,还存在诸多不足.主要总结其在管理、质量、利用、信息化建设、管理对象等方面存在的不足,从利益相关者角度分析影响因素,并针对政府、基层医疗卫生机构、卫生人员这三方具有较大影响力的利益相关者提出促进健康档案实施建议.     

论《周易参同契》的“变形而仙”说

魏伯阳所撰《周易参同契》是运用《周易》原理来支撑金丹之道的滥觞。它以《周易》的变易原理作为道教神仙存在学说的理论基础,通过论说"物性可变",进而说明人也可变。人通过服炼金丹能够变化自己的身体而为神仙之体,即"変形而仙",从而可以超越生死。"变形而仙"思想并非《参同契》独创,而是有所本的。这一思想对后世道教产生了巨大而深远的影响,如葛洪、陶弘景、沈汾等人皆明显继承了《参同契》的"变形而仙"说。     

词切分对语文学优生与学困生阅读影响的眼动研究

采用EyeLink II眼动仪,以小学二年级语文学优生和学困生为被试,考察词切分对句子阅读的影响.实验设置四种空格呈现条件:正常无空格条件、字间空格条件、词间空格条件和非词空格条件.研究表明:(1)小学二年级学生阅读词间空格文本、字间空格文本和正常无空格文本效果相同.(2)与语文学优生相比,学困生阅读任何条件的句子需要更多的注视时间和注视次数.非词空格呈现条件对学困生的干扰更大,表明学困生更依赖文本的低水平信息.文章最后探讨了汉语阅读的基本信息单元问题.     

不确定性决策违背“确定事件原则”的心理机制再探

不确定性决策违背＂确定事件原则＂的心理机制再探从决策理由切入,在现实情境中考察了违背确定事件原则（sure-thing principle）的心理机制,检验了基于理由（reason-based）的假设。研究结果表明,违背确定事件原则的被试在不确定条件下知觉到的理由冲突程度显著高于遵循确定事件原则的被试在不确定条件下知觉到的理由冲突程度;违背确定事件原则的被试在不确定条件下知觉到的理由清晰程度显著低于其在两种确定条件下知觉到的理由清晰程度,而遵循确定事件原则的被试在不确定条件下知觉到的理由清晰程度则介于其在两种确定条件下知觉到的理由清晰程度之间。研究结果支持了基于理由的假设。     

左右半脸及其位置对面孔吸引力的影响

本研究将拼嵌技术（chimera technique）和融合技术（Morph tech—nique）结合起来,制作新形式的面孔刺激,将“刺激”和“位置”分离并分别操纵,检验了左右半脸及其位置对面孔吸引力的影响。实验结果显示：（1）“刺激”和“位置”都会影响面孔吸引力;（2）“刺激”的影响是直接的,具体表现为右半脸不论呈现在面孔的左侧还是右侧,其吸引力总是高于左半脸的吸引力;（3）“位置”的影响模式较为复杂,具体表现为左右半脸在原始位置呈现时（右丰脸呈现在右侧,左半脸呈现在左侧）,其吸引力总是高于镜像位置。     

Stress induces glucocorticoid-mediated apoptosis of rat Leydig cells in vivo

Stress can disrupt endocrine signalling in the male reproductive axis through high concentrations of glucocorticoids, the hallmark of stress. Our previous work revealed that a stress level of exogenous glucocorticoids could induce apoptosis of rat Leydig cells, which are the primary source of testosterone. The aim of this study was to investigate whether stress can induce apoptosis in rat Leydig cells in vivo and, if so, whether the process is the result of a direct effect of glucocorticoids. In a chronically stressed rat model, serum corticosterone concentration was increased significantly whereas serum testosterone was decreased. The frequency of apoptotic Leydig cells in stressed rats was also increased. Adrenalectomised rats subjected to chronic stress showed an elevated serum testosterone, while the apoptotic frequency of Leydig cells was not increased. It was established that glucocorticoid-induced Leydig cell apoptosis is mediated by glucocorticoid receptors (GRs), which translocate from cytoplasm to nucleus. Adenovirus microRNA-induced downregulation of GR expression in vitro alleviated the corticosterone-induced increase in apoptosis of Leydig cells. These results indicate that the stress-induced increase in corticosterone secretion resulted in apoptosis in rat Leydig cells in vivo, and thereby decreased testosterone synthesis.     

Sequence effects by non-predictive arrow cues

Previous studies have found that attention orienting is influenced by the orienting processes of previous trials in a spatial cueing paradigm. This study mainly investigated whether this sequence effect could happen for a non-predictive arrow cue and whether it was influenced by the cue-target SOAs in previous and current trials. A significant sequence effect was observed for arrow cues even when voluntary control was not required, and it was significantly influenced by the SOAs of previous trials. The present results support the automatic memory check hypothesis and may reflect some temporal characteristics of the memory mechanism in sequential processes. In addition, contrary to the previous findings, we found an overall response facilitation following a catch trial, suggesting that the influence of preceding catch trials may be sensitive to experimental contexts.     

Cue effectiveness in communicatively efficient discourse production

Recent years have seen a surge in accounts motivated by information theory that consider language production to be partially driven by a preference for communicative efficiency. Evidence from discourse production (i.e., production beyond the sentence level) has been argued to suggest that speakers distribute information across discourse so as to hold the conditional per-word entropy associated with each word constant, which would facilitate efficient information transfer (Genzel & Charniak, 2002). This hypothesis implies that the conditional (contextualized) probabilities of linguistic units affect speakers' preferences during production. Here, we extend this work in two ways. First, we explore how preceding cues are integrated into contextualized probabilities, a question which so far has received little to no attention. Specifically, we investigate how a cue's maximal informativity about upcoming words (the cue's effectiveness) decays as a function of the cue's recency. Based on properties of linguistic discourses as well as properties of human memory, we analytically derive a model of cue effectiveness decay and evaluate it against cross-linguistic data from 12 languages. Second, we relate the information theoretic accounts of discourse production to well-established mechanistic (activation-based) accounts: We relate contextualized probability distributions over words to their relative activation in a lexical network given preceding discourse.     

惊反射在创伤后应激障碍研究中的应用:高唤醒与恐惧抑制

创伤后应激障碍(PTSD)是唯一在诊断标准中包含惊反射改变的精神疾病.相比自我报告法,对惊反射的实验室测量与总体症状关联更紧密,并已积累了较多神经机制研究成果,可作为连接前临床与临床研究的桥梁.在惊反射应用于PTSD研究的初期,它主要作为PTSD患者高唤醒症状的客观指标,但是尚未发现惊反射强度的变化与总体症状的明确关系.近年来,惊反射与情境性焦虑、恐惧抑制等新范式结合,发现特定情境下惊反射改变是PTSD患者特有的表现.惊反射在创伤应激障碍研究中所取得的新进展对PTSD病理机制的探索和临床诊断都有所启发和推进.     

情绪Stroop效应：威胁驱动还是反应偏差？

为了考查情绪Stroop效应的产生机制是威胁驱动还是反应偏差,本研究进行了两个实验.实验一用一般负性情绪词语和中性词语作为实验材料,实验二用威胁性的情绪图片和中性图片作为实验材料.每个实验均要求一组被试做按键反应,另一组被试做摇杆反应.结果发现,当实验材料为词语时,未出现情绪Stroop效应;当实验材料为威胁性图片时,无论是趋向性反应方式还是回避性反应方式,都出现了情绪Stroop效应.本研究结果支持威胁驱动机制.