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31.
Yago E Duarte A Wong T Barceló F Knight RT 《Cognitive, affective & behavioral neuroscience》2004,4(4):609-617
Single-unit, event-related potential (ERP), and neuroimaging studies have implicated the prefrontal cortex (PFC) in top-down
control of attention and working memory. We conducted an experiment in patients with unilateral PFC damage (n=8) to assess the temporal kinetics of PFC-extrastriate interactions during visual attention. Subjects alternated attention
between the left and the right hemifields in successive runs while they detected target stimuli embedded in streams of repetitive
task-irrelevant stimuli (standards). The design enabled us to examine tonic (spatial selection) and phasic (feature selection)
PFC-extrastriate interactions. PFC damage impaired performance in the visual field contralateral to lesions, as manifested
by both larger reaction times and error rates. Assessment of the extrastriate P1 ERP revealed that the PFC exerts a tonic
(spatial selection) excitatory input to the ipsilateral extrastriate cortex as early as 100 msec post stimulus delivery. The
PFC exerts a second phasic (feature selection) excitatory extrastriate modulation from 180 to 300 msec, as evidenced by reductions
in selection negativity after damage. Finally, reductions of the N2 ERP to target stimuli supports the notion that the PFC
exerts a third phasic (target selection) signal necessary for successful template matching during postselection analysis of
target features. The results provide electrophysiological evidence of three distinct tonic and phasic PFC inputs to the extrastriate
cortex in the initial few hundred milliseconds of stimulus processing. Damage to this network appears to underlie the pervasive
deficits in attention observed in patients with prefrontal lesions. 相似文献
32.
Nigg JT Glass JM Wong MM Poon E Jester JM Fitzgerald HE Puttler LI Adams KM Zucker RA 《Journal of abnormal psychology》2004,113(2):302-314
One component of individual risk for alcoholism may involve cognitive vulnerabilities prodromal to alcoholism onset. This prospective study of 198 boys followed between 3 and 14 years of age evaluated neurocognitive functioning across three groups who varied in familial risk for future alcoholism. Measures of intelligence, reward-response, and a battery of neuropsychological executive and cognitive inhibitory measures were used. Executive functioning weaknesses were greater in families with alcoholism but no antisocial comorbidity. IQ and reward-response weaknesses were associated with familial antisocial alcoholism. Executive function effects were clearest for response inhibition, response speed, and symbol-digit modalities. Results suggest that executive deficits are not part of the highest risk, antisocial pathway to alcoholism but that some executive function weaknesses may contribute to a secondary risk pathway. 相似文献
33.
Hong YY Chan G Chiu CY Wong RY Hansen IG Lee SL Tong YY Fu HY 《Journal of personality and social psychology》2003,85(6):1147-1160
Social identity approaches assume that social identification affects both self-conception and intergroup orientation. The authors contend that such social identification effects are accentuated when people hold a fixed view of human character and attribute immutable dispositions to social groups. To these individuals, social identities are immutable, concrete entities capable of guiding self-conception and intergroup orientation. Social identification effects are attenuated when people hold a malleable view of human character and thus do not view social identities as fixed, concrete entities. The authors tested and found support for this contention in three studies that were conducted in the context of the Hong Kong 1997 political transition, and discussed the findings in terms of their implications for self-conceptions and the meaning of social identification. 相似文献
34.
Temporal integration of speech prosody is shaped by language experience: an fMRI study 总被引:5,自引:0,他引:5
Gandour J Dzemidzic M Wong D Lowe M Tong Y Hsieh L Satthamnuwong N Lurito J 《Brain and language》2003,84(3):318-336
Differences in hemispheric functions underlying speech perception may be related to the size of temporal integration windows over which prosodic features (e.g., pitch) span in the speech signal. Chinese tone and intonation, both signaled by variations in pitch contours, span over shorter (local) and longer (global) temporal domains, respectively. This cross-linguistic (Chinese and English) study uses functional magnetic resonance imaging to show that pitch contours associated with tones are processed in the left hemisphere by Chinese listeners only, whereas pitch contours associated with intonation are processed predominantly in the right hemisphere. These findings argue against the view that all aspects of speech prosody are lateralized to the right hemisphere, and promote the idea that varying-sized temporal integration windows reflect a neurobiological adaptation to meet the 'prosodic needs' of a particular language. 相似文献
35.
Dynamic variations in affective priming 总被引:9,自引:0,他引:9
The present study investigates the dynamics of emotional processing and awareness using an affective facial priming paradigm in conjunction with a multimodal assessment of awareness. Key facial primes are visually masked, and are presented for brief (unconscious) and extended (conscious) durations. Using a preference measure, we examine whether the effects of the primes differ qualitatively (Murphy & Zajonc, 1993). We show that: (a) unconscious affective priming with faces emerges strongly in initial presentations and diminishes rapidly with repetition; (b) conscious affective priming also emerges strongly in initial presentations, however it persists in strength with repetition; and (c) in contrast to other reports on the salience of negative stimuli, happy faces appear more salient than sad faces when presented outside awareness. We discuss the limits and extensions of unconscious affective priming with faces, and consider several methodological and conceptual questions concerning emotional processing out of awareness. 相似文献
36.
Wong A Escobar M Lesage A Loyer M Vanier C Sakinofsky I 《Suicide & life-threatening behavior》2001,31(1):103-112
Media reports connecting UN peacekeeping duties by Canadian soldiers to their subsequent suicide prompted this study of peacekeeping as suicide risk. In a case-control design we retrospectively compared 66 suicides in the Canadian military between 1990 and 1995 with two control groups: (a) 2,601 controls randomly selected from the electronic military database and (b) 66 matched controls with complete personnel and medical data. We found no increased risk of suicide in peacekeepers except among a subgroup of air force personnel. Here confounding individual factors, isolation from supports, and possibly inadequate preparation for deployment elucidated their suicides. Theater of deployment (e.g., Bosnia) did not affect the suicide rate. Military suicides experienced psychosocial stresses and psychiatric illness more often than their matched controls. We conclude that although peacekeeping per se does not increase overall suicide risk, military life-styles may strain interpersonal relationships, encourage alcohol abuse, and contribute to psychiatric illness and suicide in a minority of vulnerable individuals irrespective of peacekeeping assignment. Careful selection, and preparatory military training that encourages intragroup bonding and mutual support, may protect against suicide risk. 相似文献
37.
Schroeder SR Oster-Granite ML Berkson G Bodfish JW Breese GR Cataldo MF Cook EH Crnic LS DeLeon I Fisher W Harris JC Horner RH Iwata B Jinnah HA King BH Lauder JM Lewis MH Newell K Nyhan WL Rojahn J Sackett GP Sandman C Symons F Tessel RE Thompson T Wong DF 《Mental retardation and developmental disabilities research reviews》2001,7(1):3-12
This paper summarizes a conference held at the National Institute of Child Health and Human Development on December 6-7, 1999, on self-injurious behavior [SIB] in developmental disabilities. Twenty-six of the top researchers in the U.S. from this field representing 13 different disciplines discussed environmental mechanisms, epidemiology, behavioral and pharmacological intervention strategies, neurochemical substrates, genetic syndromes in which SIB is a prominent behavioral phenotype, neurobiological and neurodevelopmental factors affecting SIB in humans as well as a variety of animal models of SIB. Findings over the last decade, especially new discoveries since 1995, were emphasized. SIB is a rapidly growing area of scientific interest to both basic and applied researchers. In many respects it is a model for the study of gene-brain-behavior relationships in developmental disabilities. 相似文献
38.
Wong PS 《Journal of the American Psychoanalytic Association》1999,47(3):817-841
A central tenet of psychoanalysis, and arguably of any comprehensive theory of mind, is the existence of a psychological unconscious. Years of clinical investigation into the nature of unconscious processes have facilitated the development of psychoanalysis as a clinical method. Empirical investigations of unconscious mental processes, however, have lagged behind clinical inquiry. With few exceptions, attempts to understand unconscious processes using rigorous experimental controls have remained sequestered in scientific domains other than psychoanalysis, where they have proliferated recently. In view of this recent upsurge of research on unconscious processes outside of psychoanalysis, efforts to integrate such knowledge into general theories of psychopathology and clinical investigation are critical. In this paper, an interdisciplinary approach is taken to the study of one aspect of unconscious mental functioning--what Freud originally termed signal anxiety. Signal anxiety is examined using information from cognitive psychology and learning theory, psychophysiology, behavioral neuroscience, and psychoanalytic theory. Though the original concept of signal anxiety is supported by recent research, it is concluded that signal anxiety is probably best thought of not as the affect of anxiety but as a subset of unconscious mental processes that have a signal function of anticipating danger. Such unconscious anticipatory processes are a general feature of the mind that includes responses to both real and imagined (neurotic) appraisals of a situation. The neurophysiological structures and processes associated with unconscious anticipation in humans are just beginning to be understood. 相似文献
39.
The type of experience involved with an object category has been regarded as one important factor in shaping of the human
object recognition system. Laboratory training studies have shown that different kinds of learning experience with the same
set of novel objects resulted in different perceptual and neural changes. Whether this applies to natural real-world objects
remains to be seen. We compared two groups of observers who had different learning experiences with faces, using holistic
processing as a dependent measure. We found that, while ordinary observers had extensive individuation experience with faces
and displayed typical holistic face processing, art students who had acquired additional experience in drawing faces, and
thus in attending to parts of a face, showed less holistic processing than did ordinary observers. These results converge
with laboratory training studies on the role of type of experience in the development of different perceptual markers for
different object categories. It is thus insufficient to categorize expertise simply in terms of object domains (e.g., expertise
with faces). Instead, perceptual expertise should be classified in terms of the underlying process or task demand. 相似文献
40.
Emotional events tend to be retained more strongly than other everyday occurrences, a phenomenon partially regulated by the neuromodulatory effects of arousal. Two experiments demonstrated the use of relaxing music as a means of reducing arousal levels, thereby challenging heightened long-term recall of an emotional story. In Experiment 1, participants (N=84) viewed a slideshow, during which they listened to either an emotional or neutral narration, and were exposed to relaxing or no music. Retention was tested 1 week later via a forced choice recognition test. Retention for both the emotional content (Phase 2 of the story) and material presented immediately after the emotional content (Phase 3) was enhanced, when compared with retention for the neutral story. Relaxing music prevented the enhancement for material presented after the emotional content (Phase 3). Experiment 2 (N=159) provided further support to the neuromodulatory effect of music by post-event presentation of both relaxing music and non-relaxing auditory stimuli (arousing music/background sound). Free recall of the story was assessed immediately afterwards and 1 week later. Relaxing music significantly reduced recall of the emotional story (Phase 2). The findings provide further insight into the capacity of relaxing music to attenuate the strength of emotional memory, offering support for the therapeutic use of music for such purposes. 相似文献