Practice and Persuasive Frame: Effects on Beliefs,Intention, and Performance of a Cancer Self-Examination1

Many behaviors are performed less frequently than intended because they require knowledge and skill to overcome behavioral barriers. This experiment tested effects of two factors, direct experience and message frame, that were hypothesized to affect men's intention to perform the testicle self-exam for cancer (TSE) and their actual exam performance, in part by affecting their knowledge and beliefs about overcoming TSE performance barriers. Men's experience performing the TSE on a life-like model and the frame (negative, positive, or neutral) of the recommendation promoting the exam were manipulated factorially. Consistent with prediction, men who practiced (vs. did not practice) the self-exam: (a) endorsed stronger beliefs about behavior-specific knowledge (e.g., ability to imagine a lump), (b) held more positive intention, and (c) translated that intention more consistently into self-reported action, in part because their behavior-specific knowledge increased their tendency to act on their intention. Consistent with action phase theory (Gollwitzer, 1990), intention related more strongly to behavior-specific beliefs than to general, long-term beliefs, and more strongly than attitude related to behavior-specific beliefs. These findings have practical and theoretical implications for promoting healthful and other intended behaviors.     

Data selection and responsible conduct: Was millikan a fraud?

This paper addresses a problem in reporting scientific research. The problem is how to distinguish between justifiable and unjustifiable data selection. Robert Millikan is notorious for an infamous remark that he used all his data when in fact he had used a selection. On this basis he has been accused of fraud. There is a tension here — historians and his defenders see his selection as understandable and legitimate, while current statements about the Responsible Conduct of Research imply his selection was illegitimate. This paper discusses two main issues that arise in assessing his conduct, whether he was intentionally misleading and whether he actually did mislead the scientific community about some facts of nature. It is argued that he was not intentionally misleading, and that it is unlikely that he misled the scientific community.     

Pharmacological dissociation of memory: anisomycin, a protein synthesis inhibitor, and leupeptin, a protease inhibitor, block different learning tasks

Inhibition of protein synthesis by anisomycin for a short duration impairs memory of a one-trial inhibitory avoidance task in rats. Memory of escape conditioning involving eight trials is disrupted only if the duration of protein synthesis is prolonged by repeated injections. In marked contrast, olfactory memory of rats trained on two odor discriminations is not affected by anisomycin even if the duration of inhibition is prolonged and the number of trials is reduced to a minimum. In previous work, leupeptin, a thiol proteinase inhibitor, was shown to impair olfactory discrimination learning, but left inhibitory and avoidance conditioning intact. Together, these results provide a pharmacological double dissociation of memory, and suggest that the same chemistries, or mixtures of chemistries, may not be involved in all types of memory.     

Exploration and avoidance in rats with lesions in amygdala and piriform cortex

Lesions localized to specific areas of the amygdala and overlying cortex in rats produced differential effects in several behavioral tasks. Three different types of lesions were tested: central, basolateral, and cortex lateral to the amygdala. Lesions restricted to the central nucleus produced increased activity on all parameters studied in an open-field test, but the other two groups were not changed. In one-way active avoidance all three groups with lesions showed deficits. The most pronounced change was observed in the central group. All groups showed the same degree of retention loss, but in forced extinction of one-way active avoidance after retraining, the cortical and basolateral groups were most defective. A fear-reduction hypothesis is proposed for the central lesion. The basolateral and cortical areas may be more specifically involved in passive avoidance behavior.     

Differential indications for desipramine--results of a controlled multiclinical study]

The antidepressants desipramine and imipramine were compared within the framework of a multiclinical study performed under the conditions of a controlled clinical experiment. There has been found a time-different remission of affective symptoms, which was not detectable for the inhibition of drive. The tachythymoleptic action of desipramine is discussed with reference to these results. Evaluation of the possibility of controlling affects shows different ranges of activity of desipramine and imipramine, with desipramine influencing especially negative psychoenergetic symptoms in the area of drives and emotions and imipramine, restrictive symptoms in addition to differential phenomena of the psychomotor expression.     

Why child neuropsychiatry?]

The author gives a brief survey of the development of Child-Neuropsychiatry in the G.D.R. and subsequently gives reasons for the decision in favor of the unity of neurology and psychiatry as applied to children and juveniles, which is in contrast to developments in other countries. In addition to hygienic, economic, organizational, and medical considerations, this decision was also determined by the fact that a Child-Neuropsychiatrist must, in his practical work as a subspecialist, be able to head a multiprofessional team and, thus, help assure optimum development of a child's personality.     

A tether system for psychophysiological studies in the dog

A system for monitoring blood pressure or other physiological variables in the unanesthetized and chronically instrumented dog is described. An indwelling catheter attaches to a pressure transducer affixed to the underside of a leather shield, which snaps onto a custom-fitted leather vest worn by the dog. The transducer cable ascends vertically through a hollow, flexible, stainless steel tether, which is attached at the lower end to the leather shield and at the upper end to a fluid and electrical swivel. The swivel is attached to an overhead counterbalanced boom assembly, which moves in concert with the dog, maintaining a constant minimal tension on the tether. The boom assembly is attached to a wall plate via a universal joint approximately 7 ft above floor level. Dogs can be maintained comfortably in this system 24 h/day over periods of months, with freedom of posture and movement, including rotational behavior. The system is economical to construct and provides versatile stimulation and record-ing capability and reliable long-term performance.     

The treatment of epilepsies with Convulsofin

The testing of Convulsofin carried out in 220 patients at 14 clinics over a period of six months confirms the international experience gained with valproic acid and sodium valproinate. The main field of application of Convulsofin according to the experience gained will again be the treatment of fits in generalised primary epilepsy for which it permits to carry out a monotherapy to a remarkable extent. The favourable effect of the preparation in photosensitivity could be confirmed. Also in generalised secondary epilepsy and in fits of partial epilepsy. Convulsofin is partly effective, so that it can recommended as a co-medication in the treatment of therapy-resistant forms of these epilepsies which are difficult to treat. Decrease in thrombocytes, transient increase in serum transaminases, gastrointestinal disorders, loss of hair and undesired increases in body-weight were the more frequently occurring side-effects.