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71.
I argue that a solution to puzzles concerning the relationship ofobjects and their properties – a version of the `bundle' theory ofparticulars according to which ordinary objects are mereologicalfusions of monadic and relational tropes – is also a solution topuzzles of material constitution involving the allegedco-location of material objects. Additionally, two argumentsthat have played a prominent role in shaping the current debate,Mark Heller's argument for Four Dimensionalism and Peter vanInwagen's argument against Mereological Universalism, are shownto be unsound given this version of the bundle theory. 相似文献
72.
This paper highlights the content of a course designed to prepare students for family practice, with emphasis on mothers as primary caregivers. A model is presented of relatively healthy family interactions characterized by co-parenting and equitable division of labor in the home. The strengths perspective is applied to family practice with mother-headed families where noncustodial fathers share responsibilities for childrearing. Challenges inherent in carrying out dual roles of wage labor and family caregiving are linked to social support and differences among women based on class, race, and ethnicity. 相似文献
73.
Kris Hardies 《Sex roles》2011,65(5-6):438-441
74.
Reneerkens OA Rutten K Akkerman S Blokland A Shaffer CL Menniti FS Steinbusch HW Prickaerts J 《Neurobiology of learning and memory》2012,97(4):370-379
A promising target for memory improvement is phosphodiesterase type 5 (PDE5), which selectively hydrolyzes cyclic guanosine monophosphate (cGMP). In rodents, PDE5 inhibitors (PDE5-Is) have been shown to improve memory performance in many behavioral paradigms. However, it is questioned whether the positive effects in animal studies result from PDE5 inhibition in the central nervous system or the periphery. Therefore, we studied the effects of PDE5 inhibition on memory and determined whether compound penetration of the blood-brain barrier (BBB) is required for this activity. Two selective PDE5-Is, vardenafil and UK-343,664, were tested in the object recognition task (ORT) in both a MK-801- and scopolamine-induced memory deficit model, and a time-delay model without pharmacological intervention. Compounds were dosed 30 min before the learning trial of the task. To determine if the PDE5-Is crossed the BBB, their concentrations were determined in plasma and brain tissue collected 30 min after oral administration. Vardenafil improved object recognition memory in all three variants of the ORT. UK-343,664 was ineffective at either preventing MK-801-induced memory disruption or time-dependent memory decay. However, UK-343,664 attenuated the memory impairment of scopolamine. Vardenafil crossed the BBB whereas UK-343,664 did not. Further, co-administration of UK-343,664 and scopolamine did not alter the brain partitioning of either molecule. This suggests that the positive effect of UK-343,664 on scopolamine-induced memory decay might arise from peripheral PDE5 inhibition. The results herein suggest that there may be multiple mechanisms that mediate the efficacy of PDE5 inhibition to improve memory performance in tasks such as the ORT and that these involve PDE5 located both within and outside of the brain. To further elucidate the underlying mechanisms, the cellular and subcellular localization of PDE5 needs to be determined. 相似文献
75.
76.
Two experiments examined whether a source credibility effect would be observed for a syllogistic reasoning task. In the experiments,
people were given two statements, presented as the results from a survey, followed by a conclusion that was supposedly made
by one of two sources. In Experiment 1, one of the sources was described as honest and the other as dishonest, and in Experiment 2, one of the sources was described as an expert and the other as a non-expert. Because a pilot experiment showed that credibility
can be overridden by people’s experience with a source, all conclusions in Experiments 1 and 2 were ones that were likely to be accepted (i.e., necessary and possible strong conclusions). Both experiments showed a clear
source credibility effect, particularly for the invalid conclusions. These results, along with the belief bias effect and
previous research with conditional reasoning, suggest that people can be influenced by extraneous context, such as the honesty
or expertise of a source, in a syllogistic reasoning task. 相似文献
77.
Utility functions, which relate subjective value to physical attributes of experience, are fundamental to most decision theories. Seven experiments were conducted to test predictions of the most widely assumed mathematical forms of utility (power, log, and negative exponential), and a function proposed by Rachlin (1992). For pairs of gambles for real monetary gains, undergraduate and nonstudent subjects either reported an equalizing amount for 1 outcome that made the gambles subjectively equal or chose between gambles where the amounts were varied across trial, which allowed the equalizing amount to be estimated from their pattern of choices. Using a novel method that eliminates several limitations of previous research, I manipulated the outcomes across trials such that each type of utility function predicted a linear relationship between the equalizing amounts and the amounts of the other outcomes, and made point predictions for either the slope or intercept of that relationship. In a meta-analysis across experiments, systematic departures from the point predictions were observed for each type of utility function. Thus, the data imply that despite their historical importance and incorporation in many psychological and economic decision theories, the most widely assumed models of utility are incorrect. 相似文献
78.
In a subsample of a multisite stalking study (Mohandie, Meloy, McGowan, & Williams, 2006) comprising 78 offenders from one site, 77% committed new offenses within an average follow-up of 106 months (8.8 years). Over half (56%) were charged for new stalking related offenses and 33% for violent recidivism. Violent reoffending, including sexual offenses, was predicted by risk factors consistent with existing literature: younger age at first conviction, prior release failures, and criminal history. Stalking recidivism was predicted by pre-index offending scores, using the Cormier-Lang, and prior diagnosis of a mental illness. In addition, stalkers with previously diagnosed mental illness had significantly more police contacts as complainants than those without; their recidivism was also more likely to be non-violent. 相似文献
79.
A study of 143 female stalkers was conducted, part of a large North American sample of stalkers (N=1005) gathered from law enforcement, prosecutorial, and entertainment corporate security files (Mohandie, Meloy, Green McGowan, & Williams, 2006). The typical female stalker was a single, separated, or divorced woman in her mid-30s with a psychiatric diagnosis, most often a mood disorder. She was more likely to pursue a male acquaintance, stranger, or celebrity, rather than a prior sexual intimate. When compared with male stalkers, the female stalkers had significantly less frequent criminal histories, and were significantly less threatening and violent. Their pursuit behavior was less proximity based, and their communications were more benign than those of the males. The average duration of stalking was 17 months, but the modal duration was two months. Stalking recidivism was 50%, with modal time between intervention and re-contacting the victim of one day. Any prior actual relationship (sexual intimate or acquaintance) significantly increased the frequency of threats and violence with large effect sizes for the entire female sample. The most dangerous subgroup was the prior sexually intimate stalkers, of whom the majority both threatened and were physically violent. The least dangerous were the female stalkers of Hollywood celebrities. Two of the McEwan, Mullen, MacKenzie, and Ogloff (2009b) predictor variables for stalking violence among men were externally validated with moderate effect sizes for the women: threats were associated with increased risk of violence, and letter writing was associated with decreased risk of violence. 相似文献
80.