Hypothalamo-Pituitary-Adrenocortical Regulation Following Lesions of the Central Nucleus of the Amygdala

Previous reports indicate that the central nucleus of the amygdala (CeA) stimulates adrenocorticotropin and corticosterone secretion, suggesting a role for this region in central hypothalamo-pituitary-adrenocortical (HPA) stress regulation. To evaluate this hypothesis, this study assessed the impact of CeA lesion on the response of hypophysiotrophic paraventricular nucleus (PVN) neurons to acute restraint and chronic unpredictable stress exposure. In contrast to previous reports, CeA lesions did not affect corticosterone or ACTH secretion induced by acute stress. Acute restraint increased PVN corticotropin releasing hormone (CRH) mRNA expression, increased the number of parvocellular PVN neurons expressing the co-secretagogue arginine vasopressin (AVP), and induced cFOS mRNA expression in the parvocellular PVN. However, there was no additional effect of CeA lesion on any measure of PVN activation. Chronic unpredictable stress exposure induced long-term activation of the HPA axis, noted by thymic involution, adrenal hypertrophy and increased PVN CRH mRNA expression. Stress-induced changes in thymus and adrenal weights were not affected by CeA lesion. Further, CeA lesion rats did not differ from controls in post-stress CRH mRNA expression. However, basal CRH mRNA expression was increased in the PVN of CeA rats, suggesting that the CeA plays a role in long-term inhibition of the PVN. The results of these studies are not consistent with the hypothesis that the CeA is necessary for stress-induced pituitary-adrenocortical activation. Rather, this region may play a stressor-specific modulatory role in regulation of HPA function.     

Racial differences in intelligence: The importance of the executive system

The race-IQ controversy arose at a time when psychometric views of intelligence dominated. Little attention was paid to more process-oriented models in spite of the fact they provide alternative perspectives on the causes of individual differences in problem-solving. We hypothesized that much of the IQ spread commonly observed between black and white children can be attributed to differences in components of their executive systems, including the knowledge base, control processes, and metacognitive states. To test this possibility, black and white children who differed significantly on fluid and crystallized intelligence were tested on multiple tasks reflecting components of the executive systems as well as on perceptual efficiency tasks. Striking group differences were observed in metamemory, stragegy use, and general knowledge, but few reliable differences were found in perceptual efficiency. Regression analyses showed that different factors predicted fluid and crystallized intelligence, with metamemory predicting the latter but not the former. An implication of these findings has potential educational significance: training directed at executive skills, introduce at an early age, might elevate learning and problem-solving skills in black children, thereby reducing racial differences in crystallized intelligence.     

Conflicting sex-role expectations,housework dissatisfaction,and depressive symptoms among full-time housewives

Little research has been conducted on the factors that influence a full-time homemaker's attitudes toward housework, and the influence of satisfaction with housework on psychological well-being. Data from a community survey of 134 full-time housewives showed that the greater the degree of conflict in the marital dyad over expectations for the female role, the greater the dissatisfaction of the housewife with housework. It was further demonstrated that the more dissatisfied a woman was with housework, the more likely she was to suffer from depressive symptoms. Finally, the results suggest that the greater the degree of conflict over sex-role expectations, the higher the depressive symptom score of the housewife.     

The implications of convergent and discriminant validity data for instrument validation

It seems intuitively compelling to many investigators that measurements, on the same subjects by different methods, purportedly of the same given trait are somehow better evidenced to be mutually valid measurements of that trait to the degree that they are intercorrelated. It is similarly compelling that measurements on the same subjects of purportedly different and uncorrelated traits are somehow better evidenced to be valid measurements to the degree that they are not intercorrelated. Further, a demonstration of hetero-method mono-trait intercorrelation (convergence) jointly with one of hetero-method, or preferably mono-method, hetero-trait independence (discrimination) is more compelling than either single demonstration alone [see Campbell & Fiske, 1959]. I hope to show in what follows that this intuition is misleadingunless certain rather demanding prerequisites are satisfied. Then I hope to show that contrary demonstrations are generally too indecisive to consitute validity disconfirmations. Finally, I shall consider some issues in the practical use of the indecisive multitrait-multimethod data.An earlier version of this paper was presented at the Midwestern Society of Multivariate Experimental Psychology meetings of May 1969 in Chicago. Some explication of the concept of measuring instrument has also been presented elsewhere [Krause, 1969].     

Trial of piracetam in children with cerebral organic mental deficiency]

The administration, in a double blind experiment, of piracetam to two homogeneous groups of 32 and 34 eight- to twelve-year-old brain-injured special education children lacking normal mental ability, where the daily doses administered for a period of thirteen weeks were 3 tablets or 1.2 g (administered to second and third graders) and 5 tablets or 2.0 g (administered to fourth graders), respectively, did not produce a lasting effect upon the capacity to acquire and apply knowledge, the concentration power, the proficiency level, and the behavior shown by pupils during and out of school hours. On the other hand, there was observed, in patients receiving placebos, a nonsignificant tendency toward improvement in physical well-being, so that the effect produced by the drug may here be considered to be a negative one.     

Universals and cultural differences in the judgments of facial expressions of emotion

We present here new evidence of cross-cultural agreement in the judgement of facial expression. Subjects in 10 cultures performed a more complex judgment task than has been used in previous cross-cultural studies. Instead of limiting the subjects to selecting only one emotion term for each expression, this task allowed them to indicate that multiple emotions were evident and the intensity of each emotion. Agreement was very high across cultures about which emotion was the most intense. The 10 cultures also agreed about the second most intense emotion signaled by an expression and about the relative intensity among expressions of the same emotion. However, cultural differences were found in judgments of the absolute level of emotional intensity.     

Neuromyotonic syndrome

A syndrome with constant rest activity was observed in the EMG of a 28-years-old female patient. An H-reflex was detected for normal nerve conduction velocity. Hypomagnesemia was striking among the laboratory values. Bioptic investigation yielded centralisation of nuclei, variations in the diameter of muscle fibres and a predominance of type I fibres. The findings and the response to Finlepsin point to neuromyotonic syndrome.     

Ethnic culture,religion, and the mental health of Slavic-American women

Findings of a comparative research study of women of different ethnic back-grounds suggest that the Slavic religioethnic culture acts to promote successful aging and stable mental health among women of Slavic heritage. Home and family structure, deep religiosity, and participation in church and community affiars provide function and meaningful purpose to life that tends to mitigate the losses inherent in the aging process.     

A little help from my friends: Lack of social interaction predicts greater boredom during the COVID-19 pandemic

Were people bored during the pandemic, and if so why? One possibility is lack of social interaction due to restrictions on social activity intended to slow the spread of communicable disease. In a 3-week daily diary study (n = 438; international community sample) social interaction predicted boredom and its consequences. People felt more bored on days when they engaged in less social interaction than usual (in-person or virtually), largely driven by a lack of meaning. In turn, boredom predicted lower well-being concurrently, and more virtual interaction the next day; people dispositionally higher in trait boredom also reported more solitary (but not partnered) sexual activity. In conclusion, this study suggests that maintaining social connections, even during a pandemic, may be important to mitigate boredom and improve overall well-being.