Mental imagery and dyslexia: a deficit in processing multipart visual objects?

Dyslexic and normal control subjects memorized simple line patterns inside a grid and subsequently judged whether an "X" would have fallen on the pattern had it been present in an empty grid. The patterns were letters and novel shapes. The grids were presented to the left visual field, to the right visual field, or in central vision. Dyslexic subjects had difficulty generating images of multipart patterns, but this deficit was limited to letters. The findings suggest that dyslexics may have selective difficulty integrating visual information stored in long-term memory.     

受欺负与青少年外化问题关系的“健康环境悖论”：敌意性归因的中介作用

“健康环境悖论”是指在总体受欺负水平较低的环境中, 受欺负的个体会表现出更多适应问题。本研究以来自47个班级的1764名5年级到8年级学生为被试(男生956人, 平均年龄14.46岁), 考察了班级平均受欺负水平在个体受欺负经历与外化问题间的调节作用及敌意性归因的中介作用。结果发现：(1)受欺负与外化问题的关系存在“健康环境悖论”现象, 即班级平均受欺负水平能调节个体受欺负经历与外化问题的关系, 在班级平均受欺负水平较低的班级中受欺负经历与外化问题的关联更强; (2)班级平均受欺负水平对受欺负与外化问题的调节作用通过敌意性归因的中介作用实现。本研究证实了受欺负与外化问题的健康环境悖论现象, 并首次揭示了敌意性归因的中介作用机制。     

疫病与外交：清末民初华洋互动视域下的瘟疫防治

瘟疫贯穿人类历史发展始终。近代以降,由于列强势力深入中国各地,围绕瘟疫防治而产生的华洋互动日趋频繁。一方面,外侨主导的防疫事业引发了中国社会各阶层收回防疫主权的外交诉求;另一方面,列强以防疫之名行侵略之实的行为使得华洋之间围绕国权展开了艰难博弈。在此过程之中,近代中国政府通过完善其行政能力,更有力地介入到防疫领域的管理中,推动了防疫事业的制度化发展,并以外交的方式维护公共卫生领域的国权,从而在应对公共卫生事件中逐步走向成熟。

     

温水煮青蛙：专业认同对大学生抑郁的影响机制

为探讨专业认同、学业情绪与大学生抑郁之间的关系,采用大学生专业认同问卷、青少年学业情绪问卷与抑郁自评量表对329名大学生进行调查。结果发现：（1）专业认同对大学生抑郁有显著负向预测作用;（2）专业认同对积极学业情绪均有显著正向预测作用,但只对消极低唤醒学业情绪有显著负向预测作用;（3）在专业认同对抑郁的影响中,积极低唤醒与消极低唤醒学业情绪起到完全中介作用。结果表明,专业认同对大学生抑郁的影响实际上是一种“温水煮青蛙”效应。     

利他惩罚的发生机制及其神经基础

利他惩罚是指个体为惩罚违反社会规范的人而自愿个人支付成本,它在人类合作演化过程中扮演着重要的作用。"认知控制"与"情绪满足"被用来阐述利他惩罚的产生机制。而神经层面的研究也发现,利他惩罚主要涉及以背外侧前额叶皮层为主的基于规则的系统和包括纹状体、内侧前额叶皮层以及脑岛等脑区在内的情绪驱动系统。此外,5-羟色胺、多巴胺等神经递质可能是利他惩罚行为发生的神经生化基础。未来研究除了需进一步深入探讨与整合利他惩罚的发生机制、神经机制、基因机制以外,还应注重利他惩罚在自然情境下的研究。     

Relationship of religiosity to mental health literacy,stigma, social distance,and occupational restrictiveness in Ningxia Province,China

Little research has assessed the relationship between religiosity and mental health awareness in low- and middle-income countries. This study identified a representative sample of 2,425 community-dwelling adults in Ningxia, China and administered the Duke University Religion Index, the Mental Health Knowledge Questionnaire, the Mental Health Attitude Questionnaire, the Social Distance – Personal Questionnaire and the Social Restrictiveness – Occupational Questionnaire. Religious affiliation per se was not associated with mental health literacy or attitudes, but higher levels of religiosity were associated with better awareness of mental health issues and less social distance and occupational restrictiveness of those with mental health conditions. However, these relationships were substantially different in Hui ethnicity respondents (85% of whom were practicing Islam) and Han ethnicity respondents (15% of whom practiced Buddhism, Taoism or Confucianism).     

The dynamics of multimodal integration: The averaging diffusion model

We combine extant theories of evidence accumulation and multi-modal integration to develop an integrated framework for modeling multimodal integration as a process that unfolds in real time. Many studies have formulated sensory processing as a dynamic process where noisy samples of evidence are accumulated until a decision is made. However, these studies are often limited to a single sensory modality. Studies of multimodal stimulus integration have focused on how best to combine different sources of information to elicit a judgment. These studies are often limited to a single time point, typically after the integration process has occurred. We address these limitations by combining the two approaches. Experimentally, we present data that allow us to study the time course of evidence accumulation within each of the visual and auditory domains as well as in a bimodal condition. Theoretically, we develop a new Averaging Diffusion Model in which the decision variable is the mean rather than the sum of evidence samples and use it as a base for comparing three alternative models of multimodal integration, allowing us to assess the optimality of this integration. The outcome reveals rich individual differences in multimodal integration: while some subjects’ data are consistent with adaptive optimal integration, reweighting sources of evidence as their relative reliability changes during evidence integration, others exhibit patterns inconsistent with optimality.     

母亲抑郁对青少年抑郁的影响:亲子关系的中介作用与青少年消极情绪性的调节作用

对1708名八年级青少年（平均年龄14.30±0.48岁,男生852名）及其母亲（平均年龄39.17±2.47岁）的抑郁症状、母子关系和青少年消极情绪性进行测量,考察了母亲抑郁对青少年抑郁的影响机制。结果发现：（1）母亲抑郁能够正向预测青少年的抑郁;（2）母子关系在母亲抑郁与青少年抑郁之间起中介作用,母亲抑郁既能增加母子冲突的强度,也能降低母子亲合水平,进而导致青少年的抑郁;（3）青少年消极情绪性在母亲抑郁影响青少年抑郁的中介机制中起调节作用,仅在高消极情绪性的青少年中,母子冲突能够显著预测青少年的抑郁;但消极情绪性不能调节母子亲合对青少年抑郁的影响;（4）母亲抑郁影响青少年抑郁的有调节的中介模型不存在性别差异。     

从不同高血压防治指南的比较看高血压治疗策略的变化

为减少因高血压造成的各种心血管事件,世界不同地区制定或修订了适合自己的高血压防治指南.通过对JNC7、ESH/ESC及2004年中国高血压防治指南的比较及分析,以便能更全面、正确地理解和发展我国新的高血压指南,并将该指南灵活运用于实际工作.     

从循证医学看目前冠心病的药物治疗

为使冠心病患者尽可能达到最优化的药物治疗,结合最近几年出现的大型临床研究,分析了不同冠心病患者应采取的合理药物治疗措施及可能带来的益处,并针对我国现状,提出了相应的解决方案.