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171.
Munger KM Gill CJ Ormond KE Kirschner KL 《Mental retardation and developmental disabilities research reviews》2007,13(2):121-128
Recent scientific discoveries have made it much easier to test prenatally for various genetic disabilities, such as Down syndrome. However, while many observers have heralded such "advances" for their effectiveness in detecting certain conditions, others have argued that they perpetuate discrimination by preventing the birth of children with disabilities. This article examines the ethical and social implications of the Human Genome Project for individuals with intellectual disabilities and their families. It details the critique of prenatal testing articulated by many disability rights activists as well as scholarly and professional responses to that critique. A review of the pertinent research literature includes perspectives of genetic professionals, ethicists, disability studies scholars, parents of children with disabilities, and disabled individuals themselves. Finally, the article explores how future research endeavors, policies, and practices may more effectively integrate and respect the positions of these various stakeholders. 相似文献
172.
Parallel processing across neural systems: implications for a multiple memory system hypothesis 总被引:3,自引:0,他引:3
A common conceptualization of the organization of memory systems in brain is that different types of memory are mediated by distinct neural systems. Strong support for this view comes from studies that show double (or triple) dissociations between spatial, response, and emotional memories following selective lesions of hippocampus, striatum, and the amygdala. Here, we examine the extent to which hippocampal and striatal neural activity patterns support the multiple memory systems view. A comparison is made between hippocampal and striatal neural correlates with behavior during asymptotic performance of spatial and response maze tasks. Location- (or place), movement, and reward-specific firing patterns were found in both structures regardless of the task demands. Many, but not all, place fields of hippocampal and striatal neurons were similarly affected by changes in the visual and reward context regardless of the cognitive demands. Also, many, but not all, hippocampal and striatal movement-sensitive neurons showed significant changes in their behavioral correlates after a change in visual context, irrespective of cognitive strategy. Similar partial reorganization was observed following manipulations of the reward condition for cells recorded from both structures, again regardless of task. Assuming that representations that persist across context changes reflect learned information, we make the following conclusions. First, the consistent pattern of partial reorganization supports a view that the analysis of spatial, response, and reinforcement information is accomplished via an error-driven, or match-mismatch, algorithm across neural systems. Second, task-relevant processing occurs continuously within hippocampus and striatum regardless of the cognitive demands of the task. Third, given the high degree of parallel processing across allegedly different memory systems, we propose that different neural systems may effectively compete for control of a behavioral expression system. The strength of the influence of any one neural system on behavioral output is likely modulated by factors such as motivation, experience, or hormone status. 相似文献
173.
Fourteen right-handed males were shown slides of common objects (e.g., wristwatch), familiar situations (e.g., two people shaking hands), and inkblots from a popular projective test (Holtzman, 1986) and then asked to name the object, assess the situation, or describe the most salient image emerging from the inkblot. Alpha power suppression was monitored over the left and right frontal, temporal, parietal, and occipital lobes to determine the brain circuitry responsible for the processing of each type of stimulus. When processing common objects and familiar situations there was bilateral activation of the parietal and occipital lobes; when processing inkblots, bilateral activation of the parietal and occipital lobes was again obtained, but complemented by selective activation of the right frontal lobe. The later suggests that anterior regions of the right cerebral hemisphere contribute to the generation of dynamic images like those evoked by visually ambiguous inkblots. 相似文献
174.
Prior studies suggest that knowledge and attitudes of health care professionals influence patient communication and medical decision making. To study this dynamic in the context of genetic disability, we developed a survey on health professionals' attitudes regarding disability and genetic screening and pilot-tested it on a sample of medical students, residents, and genetic counseling students (N = 85). Despite minimal experience with disability or genetics, most respondents reported feeling comfortable dealing with genetics (59%) and disability (75%). The majority felt that disability caused significant suffering for both the person (51%) and family (64%), and that research should be directed toward preventing genetic disability (62%). Similar to prior literature, perceived Quality of Life was most often based on degrees of physical and cognitive functioning, pain, and social support. However, differences were found between genetic counseling trainees and other medical trainees in their relative emphasis of social versus medical issues in questions of disability and genetic testing, and these response patterns were associated with differences in the groups' priorities for offering information about social resources. Respondents agreed that access to genetic testing and information is personal and that testing should be available upon request for oneself (68%) and to a lesser degree for one's fetus (55%) or child (41%). However, the same individuals frequently stated that society should regulate access to such technologies. Although most felt that the patient and professional should jointly make such decisions on a case-by-case basis, it was also seen as appropriate for the health care professional to occasionally decline genetic testing. It seems apparent that training and experience influence knowledge and attitudes. Therefore, it is critical to document knowledge and attitudes of various health care providers and trainees, including differences between various specialties, to improve educational interventions geared to this area. 相似文献
175.
Since as many as 20% of all college women report symptoms of eating disorders, the present study examined the relationship between self-reported eating disorder symptoms. anxiety, drinking, and retrospective reports of inconsistent parenting during childhood. 101 college women, 85% Euro-Americans of mean age 19 yr., completed an anonymous survey including questions from the Eating Disorder Index-1, the Retrospective Family Unpredictability Scale, the Trait Anxiety Scale, and measures of drinking in the previous month. Eating disorder symptoms correlated with self-reported drinking quantity, anxiety, and retrospective ratings of inconsistent discipline. This appears to be the first time eating disorder symptoms have been associated with inconsistent discipline. Implications for etiology and treatment of eating disorders are discussed. 相似文献
176.
Research suggests that people initially take their subjective experience of an object as an accurate reflection of the object's properties, and only subsequently, occasionally, and effortfully consider the possibility that their experience was influenced by extraneous factors. The two studies reported here demonstrate that this is true even when the extraneous factors are the person's own dispositions. Dispositionally happy and unhappy participants were falsely told that they had been subliminally primed with words that might have influenced their moods, and were then asked to identify those words. Dispositionally happy participants were more likely than dispositionally unhappy participants to conclude that they had been primed with positive words, but only when they made these judgments under time pressure. The results are discussed in terms of correction models of human judgment. 相似文献
177.
Kelly Jakubowski Amy M. Belfi Lia Kvavilashvili Abbigail Ely Mark Gill Gemma Herbert 《British journal of psychology (London, England : 1953)》2023,114(3):580-604
Previous research has found that music brings back more vivid and emotional autobiographical memories than various other retrieval cues. However, such studies have often been low in ecological validity and constrained by relatively limited cue selection and predominantly young adult samples. Here, we compared music to food as cues for autobiographical memories in everyday life in young and older adults. In two separate four-day periods, 39 younger (ages 18–34) and 39 older (ages 60–77) adults recorded their music- and food-evoked autobiographical memories in paper diaries. Across both age groups, music triggered more frequent autobiographical memories, a greater proportion of involuntary memories, and memories rated as more personally important in comparison to food cues. Age differences impacted music- and food-evoked memories similarly, with older adults consistently recalling older and less specific memories, which they rated as more positive, vivid, and rehearsed. However, young and older adults did not differ in the number or involuntary nature of their recorded memories. This work represents an important step in understanding the phenomenology of naturally occurring music-evoked autobiographical memories across adulthood and provides new insights into how and why music may be a more effective trigger for personally valued memories than certain other everyday cues. 相似文献
178.
Carman Sue Gill Casey Barrio Minton Jane Myers 《Adultspan: Theory Research & Practice》2015,14(2):66-76
Researchers have suggested strategies in the spiritual domain for improving wellness. This study explored relationships among spirituality, religiosity, and wellness for poor, rural women in early adulthood, early–middle adulthood, and middle–later adulthood. Implications for evidence‐based strategies to improve wellness for poor, rural women across the life span are provided. 相似文献
179.
Michael B. Gill 《British Journal for the History of Philosophy》2016,24(6):1117-1135
Shaftesbury believed that the height of virtue was impartial love for all of humanity. But Shaftesbury also harboured grave doubts about our ability to develop such an expansive love. In The Moralists, Shaftesbury addressed this problem. I show that while it may appear on the surface that The Moralists solves the difficulty, it in fact remains unresolved. Shaftesbury may not have been able to reconcile his view of the content of virtue with his view of our motivational psychology. 相似文献
180.