A flavor paired with lithium chloride blocks the formation of a pentobarbital-lithium chloride association

Thirsty rats were used in order to determine whether a vinegar solution, which had been paired with an injection of lithium chloride, could block the formation of an association between a pentobarbital- and a lithium chloride-induced state. During phase 1 the rats in the blocking group had a 2.0% vinegar solution paired with an injection of 240 mg/kg of lithium chloride, during phase 2 these rats were reexposed to the vinegar prior to each injection of 20 mg/kg of pentobarbital and 240 mg/kg of lithium chloride, and during phase 3 these rats were given access to a novel 0.75% saccharin solution and were injected with pentobarbital after saccharin removal. Animals with this history did not form an association between the pentobarbital- and lithium chloride-induced states during phase 2 as evidenced by their refusal to consume the saccharin solution over repeated pairings of saccharin with pentobarbital during phase 3. Control groups that received forward pairings of pentobarbital and lithium chloride, in the absence of a previously conditioned vinegar solution during phase 2, formed an association between pentobarbital and lithium chloride. These findings indicate that drug states and flavors can interfere with each others' capacity to predict the occurrence of lithium chloride.     

The effects of auditory streaming on duplex perception

When a formant transition and the remainder of a syllable are presented to subjects' opposite ears, most subjects perceive two simultaneous sounds: a syllable and a nonspeech chirp. It has been demonstrated that, when the remainder of the syllable (base) is kept unchanged, the identity of the perceived syllable will depend on the kind of transition presented at the opposite ear. This phenomenon, called duplex perception, has been interpreted as the result of the independent operation of two perceptual systems or modes, the phonetic and the auditory mode. In the present experiments, listeners were required to identify and discriminate such duplex syllables. In some conditions, the isolated transition was embedded in a temporal sequence of capturing transitions sent to the same ear. This streaming procedure significantly weakened the contribution of the transition to the perceived phonetic identity of the syllable. It is likely that the sequential integration of the isolated transition into a sequence of capturing transitions affected its fusion with the contralateral base. This finding contrasts with the idea that the auditory and phonetic processes are operating independently of each other. The capturing effect seems to be more consistent with the hypothesis that duplex perception occurs in the presence of conflicting cues for the segregation and the integration of the isolated transition with the base.     

Visual perception of surface curvature: psychophysics of curvature detection induced by motion parallax

The continuous approach to optic-flow processing shows that the curvature of a moving surface is related to a second spatial derivative of the velocity field, the spin variation (Droulez & Cornilleau-Pérès, 1989). With this approach as a theoretical framework, visual sensitivity to the curvature of a cylinder in motion was measured using a task of discrimination between cylindrical and planar patches. The results confirm the predictions suggested by the theory: (1) Sensitivity to curvature was always greater when the cylinder axis and the frontal translation were parallel than when they were orthogonal. The ratio of curvature detection thresholds in the two cases was between 1.3 and 2.5; the value predicted from the spin variation theory is about 2. (2) Sensitivity to curvature increased strongly with the velocity of the motion but was only weakly affected by its amplitude and the duration of viewing for the range of values used in our experiments.     

Semantic congruity effects in perceptual comparisons

Semantic congruity effects occur when, as in Experiment 1, for example, the time to select the shorter of two relatively short lines is faster than the time to select the longer; conversely, selection of the longer of two relatively long lines is faster than selection of the shorter. Semantic congruity effects are also demonstrated in experiments requiring comparisons of the heaviness of weights (Experiment 2) and horizontal extent (Experiment 3). In Experiment 1, the magnitude of the semantic congruity effect was larger under conditions emphasizing accuracy rather than speed and when the comparison was difficult. In fact, when comparisons were errorless, the effect was minimal (20 msec), thereby replicating previous failures to obtain the effect with supraliminal perceptual comparisons (Banks, Mermelstein, & Yu, 1982; Marschark & Paivio, 1981; Petrusic & Baranski, 1988a). In confirmation of Henmon's (1911) introspective analyses of psychophysical comparisons, Experiments 2 and 3 extend the range of the semantic congruity effect to include judgments of confidence. However, in each of the three experiments, semantic congruity effects were not evident with the response-accuracy measure. Finally, using highly confusable stimuli, in Experiment 3 the magnitude of the semantic congruity effect was shown to be larger for error than for correct response times. The implications of these findings for a decisional locus of the effect and for the semantic coding theory are discussed.     

Normal cerebrospinal fluid findings in spinal tumors--an analysis of 503 cases

Till now almost nothing has been published about normal liquor findings in spinal cord tumours. Out of 503 cases there were normal findings of total proteins and cells in 30 cases (6 per cent). A connection with the severity of the compression-syndrome was not evident. Nevertheless liquor examinations are important in diseases of the medulla spinalis. This is especially useful in the differential diagnostical demarcation of inflammable spinal cord diseases, accompanying reactions or bleedings into the spinal channel.     

Age differences in cardiovascular and cognitive performance under noise conditions

Ambient white noise (80 dB), compared with quiet (52-dB) testing conditions, improved the performance of elderly and younger subjects on simple addition. Reliable age-related interactions were found on health measures of systolic and diastolic blood pressure, as well as heart rate. Heightened sensory conditions reduced the physiological measures of arousal in the younger group, whereas significant cardiovascular reactivity was found among the older group. The results are suggestive of the potential for increased cardiovascular risk as a function of sensory stimulation in the elderly despite improvements on cognitive tasks. Additional research is needed to evaluate the multidimensional effects of extended sensory stimulation on the elderly.     

Objective and simulated stimulation: an empirical study of the effect of indirect suggestion on motor behavior

In an experimental investigation it is demonstrated that motor behavior-in contrast to the opinion forwarded in the literature-is not only elicitable by means of direct persuasion, but also to a great extend by mere indirect suggestion, (feigning of stimuli). A differential investigation of these effects provided evidence that reactions to feigned stimuli are highly person specific and relatively homogenous concerning the respective instruments whereas objective stimuli lead to reactions relatively specific for the respective instrument applied. The findings are interpreted as an analog on to placebo-effects in the area of motor behavior. Their extend may be seen as an argument for a stronger concern with subjective reaction tendencies in this field.     

Timed magnitude comparisons of numerical and nonnumerical expressions of uncertainty

Two experiments involving paired comparisons of numerical and nonnumerical expressions of uncertainty are reported. Subjects were timed under two opposing sets of instructions ("choose higher probability" vs. "choose lower probability"). Numerical comparisons were consistently faster and easier than their nonnumerical counterparts. Consistent distance and congruity effects were obtained, illustrating that both numerical and nonnumerical expressions of uncertainty contain subjective magnitude information, and suggesting that similar processes are employed in manipulating and comparing numerical and verbal terms. To account for the general pattern of results obtained, Holyoak's reference point model (1978) was generalized by explicitly including the vagueness of the nonnumerical expressions. This generalized model is based on the notion that probability expressions can be represented by membership functions (Wallsten, Budescu, Rapoport, Zwick, & Forsyth, 1986) from which measures of location for each word, and measures of overlap for each pair can be derived. A good level of fit was obtained for this model at the individual level.     

Attention deficit disorder with hyperactivity and methylphenidate: The effects of dose and mastery level on children's learning performance

This investigation examined the relationship between methylphenidate (MPH) and the learning and recall of paired associations by children with attention deficit disorder with hyperactivity (ADDH). Forty-five children with ADDH were randomly assigned to one of three groups (novel, partial mastery, and mastery learning) that varied in the amount of previous learning of paired associations and participated in a double-blind, placebo-control, repeated-measures-across-dose (crossover) design. Each child received four doses of MPH (5 mg, 10 mg, 15 mg, and 20 mg) and a placebo in a random, counterbalanced sequence. The results indicated that both the rate of acquisition and accuracy in learning paired associations were significantly, but differentially, affected by MPH dose and the degree of learning mastery. The implications of these results for psychopharmacological research and the monitoring of psychostimulant effects on children's learning performance in academic settings are discussed.The authors wish to acknowledge and express their sincere appreciation to the graduate and undergraduate student members of the Children's Learning Clinic.