Neuroreceptor imaging of stress and mood disorders

Techniques such as positron emission tomography and single photon emission computed tomography allow for the imaging of neurotransmitter receptors and transporters in the brain. These tools have been used to investigate serotonergic, dopaminergic, and opioidergic function in healthy subjects as well as in patients with major depressive disorder, bipolar disorder, and other mood disorders. Pharmacologic challenges, such as amphetamine challenge, and physiologic stressors, such as pain challenge, have been used to further examine the function of these neurotransmitter systems. Neuroimaging of patient populations before and after medication treatment may be useful to understand changes in neurotransmission that accompany disease remission. As new radiotracers with higher selectivity for the various receptors and transporters are developed, imaging techniques may provide new insights into the pathophysiology of mood disorders, leading to improved diagnosis and treatment.     

A behavior-analytic conceptualization of the side effects of psychotropic medication

A range of behavior-much deemed problematic by society-is treated with behavioral methods or psychotropic medications. Although the processes associated with behavioral interventions have been investigated using conceptual, experimental, and applied analyses, less is known about the behavioral processes associated with the use of psychotropic medication. Psychotropic drugs produce at least two types of effects of behavioral interest: (a) primary effects of drug action on target behaviors and (b) side effects that change the target or other behavior. Although an empirical literature exists regarding the former effects, little attention has been given to the latter topic. In this paper we offer a conceptual analysis of the side effects of psychotropic medication. We propose that the side effects of various drugs can influence behavior by functioning as motivating operations, conditional or discriminative stimuli, or by establishing new response-reinforcer relations. This conceptualization may facilitate the empirical analysis of how psychotropic drugs change behavior.     

Hyperlexia profiles

Two hyperlexic individuals were tested on reading outcome measures and on basic skills shown to be critical in reading acquisition. Results suggested distinct pathways to superior word recognition skills that can be described under a contemporary model of skilled reading, with differential acquisition of basic skills; superior word recognition skill was associated in both cases with specialized development in one basic area, that of orthographic processing. Results supported an asset rather than a deficit analysis of hyperlexia: Rather than assimilating to reading pathology (dyslexia) subtypes, hyperlexia was seen to be accompanied by assets that are absent in dyslexic profiles.     

Which way is upright and normal? Haptic perception of letters above head level.

In three experiments, the perception of the apparent orientation of block letters shown in various orientations above the subject's head in the horizontal plane was examined. A block letter F with its front facing down toward the observer has two crossbars on its right side; the top is the part with the long crossbar, and the base has no bar. The experiments involved changing the locations of these parts with respect to the observer. In Experiment 1, the subjects using touch most often identified a letter as having its left and right sides in a normal orientation if the front of the block letter faced upwards away from the observer, with the bar on the right and the top of the letter farther from the subject than the letter's base. In Experiment 2, the subjects judging visual uprightness favored positions in which the bars were on the right, the top of the block letter was near them, and the letter's front faced downwards toward the observer. In Experiment 3, the subjects using touch most often assessed letters as being upright if the top of the letter was the farthest part and the bar was on the right. The results suggest that, when assessing orientation, subjects using touch favored positions that would be reached by a letter moving vertically upwards from table height, but subjects relying on vision favored positions reached by a letter moving in an are centered on the subject's head (on the eyes, in particular).     

Replicating the five factor model of personality in a psychiatric sample

In this study we examined whether the factor structure and traits of the five-factor model of personality (FFM), derived from non-clinical samples, could be replicated in a sample of psychiatric patients. The revised NEO Personality Inventory (NEO PI-R) was administered to a study group of psychiatric patients (n=176). The test scores from these patients were intercorrelated, factor analyzed and the obtained factor structure was then compared to the factor structure of the normative data from the NEO PI-R. The factor structure from the psychiatric study group and that from the normative sample were virtually identical, with all five factors showing significant congruence. These results argue favorably for the clinical applicability of the FFM with psychiatric patients.     

Philosophy for Children and the Reconstruction of Philosophy

In this paper I trace the dialogical and narrative dimensions of the philosophical tradition and explore how they are reconfigured in the notion of community of philosophical inquiry (CPI), the mainstay of the collection of novels and discussion plans known as Philosophy for Children. After considering the ontology and epistemology of dialogue, I argue that narrative has replaced exposition in our understanding of philosophical discourse and that CPI represents a narrative context in which truth comes to represent the best story, in a discursive location in which there are always multiple stories. Finally, I raise the issue of children's philosophical voice. Can children philosophize, and if they can, do they do so in a voice different from adults'? If so, what are the distinctive features of that voice? I assert that it is children's historical marginalization in the Western construction of rationality that now – as that rationality undergoes its crisis – makes of them, like women and other “natives,” privileged strangers to the tradition, who are, through CPI, enabled to enter it through dialogue and narrative.     

Eye movements and variations in reading time

Summary Passages of prose were constructed which obeyed a stylistic convention referred to as dovetailing. For a given pair of sentences the final position of the first, and the initial position of the second, had the same referent. It was shown that critical dovetailed lines of text were read more rapidly than lines containing the same information, but lacking sequential structure. Degrading text by obscuring all interword spaces removed this reading time advantage. Analysis of subjects' eye movements during reading suggested that reading facilitation, induced by dovetailing, may result, not only from higher-order structural properties of text, but also from local features (particularly word-length information and associative relationships between words) known to influence eye movements.     

Psychological and Socio-cultural Adjustment during Cross-cultural Transitions: A Comparison of Secondary Students Overseas and at Home

The study further explores the distinction of psychological and socio-cultural adjustment during cross-cultural transitions. One hundred and seventy-eight New Zealand American Field Service (AFS) students residing in 23 different countries completed questionnaires which contained assessments of the following: Personality (extraversion and locus of control); life changes (Social Readjustment Rating Questionnaire); homesickness, cultural distance, acculturation (cultural identity and cultural integration—separation); attitudes toward host country; language ability; amount of contact with host and co-nationals; relationship satisfaction with co-nationals, host nationals and host family; and outcome measures of socio-cultural (social difficulty) and psychological adjustment (Profile of Mood States). Stepwise regressions revealed that homesickness, external locus of control, life changes, and social difficulty accounted for 55% of the variance in psychological adjustment. In contrast, cultural distance, language ability, satisfaction with host national contact, cultural separation and mood disturbance explained 52% of the variance in socio-cultural adaptation. In the second part of the research, psychological and socio-cultural adjustment of AFS students was compared with a sample of 142 home-based New Zealand secondary school students. Although there were no significant differences in psychological adjustment between the two groups, the students who were resident abroad experienced greater socio-cultural difficulties than the students resident in New Zealand (P < 0.0005), and, as hypothesized, the correlation between psychological and socio-cultural adjustment was significantly greater in the home-based students compared to the AFS group (P < 0.0001).     

The Effects of Names on Perception of Intelligence, Popularity, and Competence

Three experiments were conducted to explore the effects of first names on judgments of intelligence, popularity, and competence. In Experiment 1, first names that were used more often in the past than they are now (called Older Generation names) were rated by a sample of college-aged judges as less popular and less intelligent than were first names that are used more often now than in the past (called Younger Generation names). In addition, male first names tended to have higher ratings of these same qualities than did female first names. In Experiments 2 and 3, either resumes or personal ads were used to provide additional information to the raters. Results similar to those found in Experiment 1 were obtained. In general the present experiment used groups of names rather than individual names so as to control for possible irrelevant and idiosyncratic differences that might be found among individual names. Relevance to research in which men and women are compared was discussed.