Writing errors and anosognosia in amyotrophic lateral sclerosis with dementia

Amyotrophic lateral sclerosis (ALS) with dementia (ALS-D) is known to exhibit characteristics of frontotemporal dementia. However, in clinical situations, it is often difficult to evaluate their cognitive functions because of impaired voluntary speech and physical disabilities. In order to identify characteristic and diagnostic cognitive symptoms of relatively advanced ALS-D patients, we retrospectively reviewed the clinical features of seven cases of clinically definitive ALS who had dementia, impaired voluntary speech, and physical disability. Their medical records showed that six out of seven patients made writing errors, and all of the patients demonstrated anosognosia. The writing errors consisted of paragraphia such as substitution, omission, or syntactic errors with individual differences in error types. Dissociation between kana and kanji were also observed. Anosognosia was evaluated by a self-rating scale with which the patients and the medical staff evaluated the patient's physical ability; the results indicated a large discrepancy between the evaluation by the patients and the medical staff. We emphasize that aphasic writing errors have been underestimated, particularly in ALS-D patients with impaired voluntary speech. We also reported that anosognosia was the most important and quantifiable symptom in ALS-D. The relationship between writing errors and anosognosia should be investigated further.     

Examination of the content of individualism/collectivism scales in cultural comparisons of the USA and Japan

The definitions of individualism/collectivism and the content of scale items used to assess them could explain the lack of cross-cultural differences reported in some research. Specifically, existing scales may not adequately assess expected cultural differences. In study 1 , a new scale was given in Japan and the USA. Three factors were identified in both cultures. Japanese scored higher on the others focus factor but scored lower on the helping others factor than the US Americans. In study 2 , a forced choice version replicated results in study 1 . In studies 3 and 4 , the factor structure and cultural differences were replicated and the convergent and the divergent validities of the scale were examined. Results indicate that Japanese may be more others oriented depending on the item content.     

Language-specific and universal influences in children's syntactic packaging of Manner and Path: a comparison of English, Japanese, and Turkish

Different languages map semantic elements of spatial relations onto different lexical and syntactic units. These crosslinguistic differences raise important questions for language development in terms of how this variation is learned by children. We investigated how Turkish-, English-, and Japanese-speaking children (mean age 3;8) package the semantic elements of Manner and Path onto syntactic units when both the Manner and the Path of the moving Figure occur simultaneously and are salient in the event depicted. Both universal and language-specific patterns were evident in our data. Children used the semantic-syntactic mappings preferred by adult speakers of their own languages, and even expressed subtle syntactic differences that encode different relations between Manner and Path in the same way as their adult counterparts (i.e., Manner causing vs. incidental to Path). However, not all types of semantics-syntax mappings were easy for children to learn (e.g., expressing Manner and Path elements in two verbal clauses). In such cases, Turkish- and Japanese-speaking children frequently used syntactic patterns that were not typical in the target language but were similar to patterns used by English-speaking children, suggesting some universal influence. Thus, both language-specific and universal tendencies guide the development of complex spatial expressions.     

Incorporating Demographic Embeddings Into Language Understanding

Meaning depends on context. This applies in obvious cases like deictics or sarcasm as well as more subtle situations like framing or persuasion. One key aspect of this is the identity of the participants in an interaction. Our interpretation of an utterance shifts based on a variety of factors, including personal history, background knowledge, and our relationship to the source. While obviously an incomplete model of individual differences, demographic factors provide a useful starting point and allow us to capture some of this variance. However, the relevance of specific demographic factors varies between situations—where age might be the key factor in one context, ideology might dominate in another. To address this challenge, we introduce a method for combining demographics and context into situated demographic embeddings—mapping representations into a continuous geometric space appropriate for the given domain, showing the resulting representations to be functional and interpretable. We further demonstrate how to make use of related external data so as to apply this approach in low‐resource situations. Finally, we show how these representations can be incorporated into improve modeling of real‐world natural language understanding tasks, improving model performance and helping with issues of data sparsity.     

A regular arrangement of SmH2 fibres in an alpha-Fe matrix,found after the hydrogenation-disproportionation processing of Sm2Fe17

In the course of a study on microstructural changes in Sm2Fe17 during a hydrogenation-disproportionation-desorption-recombination process, a peculiar microstructure has been observed just after the hydrogenation-disproportionation processing. SmH2 crystals, formed as a result of decomposition of the Sm2Fe17 compound, are present with a fibrous shape, about 7 nm in diameter and 1 mum in length. These SmH2 fibres, all with the same orientation, are arranged at nearly regular intervals of about 11nm and with a definite orientation relationship to the alpha-Fe matrix, <110> Fe// <110> SmH2.     

Arrangement of atomic clusters in a 2/1 cubic approximant in the Al-Zn-Mg alloy system

An arrangement of the so-called Bergman clusters of atoms in a 2/1 cubic crystalline approximant phase, which is closely related to Frank-Kasper-type icosahedral quasicrystals, in an Al-Zn-Mg alloy system is discussed in detail. The 2/1 cubic structure has eight Bergman clusters in its unit cell and the positions of the clusters can be understood as twelvefold sites in the 2/1 cubic approximant of the three-dimensional Penrose lattice. The atomic clusters are located at vertices of two types of rhombohedron, which are formed by six rhombic planes with an edge length of 3 1/2 a 2 /( 2 + 1) 1/2 and a shorter diagonal of 2 a 2 /( 2 + 1) 1/2 ( is the golden ratio and a is a quasilattice constant), which correspond to half a body diagonal and an edge length respectively of the 1/1 cubic approximant unit cell. The present results provide an important key for understanding the arrangements of atomic clusters in icosahedral quasicrystals.     

Decagonal quasicrystal with ordered body-centred (CsCl-type) hypercubic lattice

An ordered structure, which was found in a decagonal quasicrystal with 0.4 nm periodicity in a conventionally solidified Al₇₀Ni₂₀Ru₁₀ alloy, has been examined theoretically by the projection of an ordered body-centred (CsCl-type) hypercubic lattice. The ordered structure can be characterized as an ordered arrangement of two kinds of atom columnar cluster with different directions of pentagonal symmetry. Two lattices, which are constructed by connecting the atom clusters in the same directions, can be interpreted as ordered sublattices formed by each of vertex and body-centred positions of the CsCl-type hypercubic lattice. Diffraction patterns calculated from the ordered and disordered body-centred hypercubic lattices replicate well the electron diffraction patterns observed from the Al-Ni-Ru and other decagonal quasicrystals.     

Participating in politics resembles physical activity: general action patterns in international archives, United States archives, and experiments

A series of studies examined whether political participation can emerge from general patterns of indiscriminate activity. In the first two studies, general action tendencies were measured by combining national and state-level indicators of high activity (e.g., impulsiveness, pace of life, and physical activity) from international and U.S. data. This action-tendency index positively correlated with a measure of political participation that consisted of voting behaviors and participation in political demonstrations. The following two experimental studies indicated that participants exposed to action words (e.g., go, move) had stronger intentions to vote in an upcoming election and volunteered more time to make phone calls on behalf of a university policy than participants exposed to inaction words did (e.g., relax, stop). These studies suggest that political participation can be predicted from general tendencies toward activity present at the national and state levels, as well as from verbal prompts suggestive of activity.     

Hemodynamic and electrophysiological connectivity in the language system: Simultaneous near-infrared spectroscopy and electrocorticography recordings during cortical stimulation

We applied near-infrared spectroscopy (NIRS) and electrocorticography (ECoG) recordings during cortical stimulation to a temporal lobe epilepsy patient who underwent subdural electrode implantation. Using NIRS, changes in blood concentrations of oxyhemoglobin (HbO(2)) and deoxyhemoglobin (HbR) during cortical stimulation of the left language areas were measured in each hemisphere. NIRS revealed that 2Hz stimulation with 5mA produced no significant hemodynamic changes in either hemisphere. By contrast, 50Hz stimulation elicited significant increases in both HbO(2) and HbR at the stimulation site. Furthermore, with 50Hz stimulation of the left superior temporal gyrus, the increases in HbO(2) and HbR were observed not only at the stimulation site but also concurrently at the left inferior frontal gyrus. This suggests the existence of functional connectivity in the language system. The present study demonstrates that simultaneous NIRS and ECoG studies during cortical stimulation allow a novel analysis of cerebral connectivity.