Prism adaptation in schizophrenia

The prism adaptation test examines procedural learning (PL) in which performance facilitation occurs with practice on tasks without the need for conscious awareness. Dynamic interactions between frontostriatal cortices, basal ganglia, and the cerebellum have been shown to play key roles in PL. Disruptions within these neural networks have also been implicated in schizophrenia, and such disruptions may manifest as impairment in prism adaptation test performance in schizophrenia patients. This study examined prism adaptation in a sample of patients diagnosed with schizophrenia (N=91) and healthy normal controls (N=58). Quantitative indices of performance during prism adaptation conditions with and without visual feedback were studied. Schizophrenia patients were significantly more impaired in adapting to prism distortion and demonstrated poorer quality of PL. Patients did not differ from healthy controls on aftereffects when the prisms were removed, but they had significantly greater difficulties in reorientation. Deficits in prism adaptation among schizophrenia patients may be due to abnormalities in motor programming arising from the disruptions within the neural networks that subserve PL.     

A Review of Spiritual and Religious Measures in Nursing Research Journals: 1995--1999

Background: A series of systematic reviews has revealed relatively high levels of interest in religion and spirituality in different nursing specialties, but not in general nursing research journals. Purpose: To identify the extent to which spirituality and religiousness were measured in all quantitative and qualitative research articles published in Research in Nursing and Health, Nursing Research, Advances in Nursing Science (ANS), and Image: The Journal of Nursing Scholarship from 1995 to 1999. Methods: A full-text search was conducted of ANS and Image using the Ovid search system. Nursing Research and Research in Nursing and Health were hand searched for spiritual/religious measures. Characteristics of selected studies, the measures taken, and their uses were coded for data analysis. Results: A total of 564 research studies were identified, of which 67 (11.9%) included at least one measure of spirituality or religiousness. A significant difference was found between the percentage of qualitative and quantitative studies that contained measures of these concepts. Of the 119 qualitative studies, 23 (19.3%) contained a measure of religion or spirituality, compared to 44 of the 445 (9.9%) quantitative studies. Nominal indicators of religious affiliation were the most commonly used measures in the quantitative studies and measures of religion and spirituality were rarely used in the analyses. Although only a few quantitative or qualitative studies intended to focus on religion or spirituality, these themes often emerged spontaneously in the qualitative research. Conclusions: Research in Nursing and Health, Advances in Nursing Science, Nursing Research, and Image: The Journal of Nursing Scholarship all published research measuring spirituality and religiousness during the time-period studied. The rate at which spirituality and religion appeared in these nursing research articles is substantially higher than that found in most fields outside of nursing. Even more frequent inclusion of spiritual and religious variables and richer measures of spirituality and religiousness would help to increase the available scientific information on the role of spirituality and religion in nursing care.     

Fragile X mental retardation protein levels increase following complex environment exposure in rat brain regions undergoing active synaptogenesis

Fragile X mental retardation protein (FMRP), which is absent in fragile X syndrome, is synthesized in vitro in response to neurotransmitter activation. Humans and mice lacking FMRP exhibit abnormal dendritic spine development, suggesting that this protein plays an important role in synaptic plasticity. Previously, our laboratory demonstrated increased FMRP immunoreactivity in visual cortex of rats exposed to complex environments (EC) and in motor cortex of rats trained on motor-skill tasks compared with animals reared individually in standard laboratory housing (IC). Here, we use immunohistochemistry to extend those findings by investigating FMRP levels in visual cortex and hippocampal dentate gyrus of animals exposed to EC or IC. Rats exposed to EC for 20 days exhibited increased FMRP immunoreactivity in visual cortex compared with animals housed in standard laboratory caging. In the dentate gyrus, animals exposed to EC for 20 days had higher FMRP levels than animals exposed to EC for 5 or 10 days. In light of possible antibody crossreactivity with closely related proteins FXR1P and FXR2P, FMRP immunoreactivity in the posterior-dorsal one-third of cerebral cortex was also examined by Western blotting following 20 days of EC exposure. FMRP levels were greater in EC animals, whereas levels of FXR1P and FXR2P were unaffected by experience. These results provide further evidence for behaviorally induced alteration of FMRP expression in contrast to its homologues, extend previous findings suggesting regulation of its expression by synaptic activity, and support the theories associating FMRP expression with alteration of synaptic structure both in development and later in the life-cycle.     

In search of the good life: a cultural odyssey in the East and West

In the first part of this article, the authors argue that any conception of well-being is culturally embedded and depends on how the notions of "well" and "being" are defined and practiced in different cultural communities. To support this argument, they conduct a comprehensive review of the empirical literature, which shows that members of individualistic and collectivistic cultures differ in their emotional experience of well-being. This difference has been traced to the indigenous psychology of selfhood in those cultures. In the second part of the article, the authors debunk the myth of infinite cultural variability, while retaining the basic insight concerning the cultural constitution of well-being. They develop a theoretical model of well-being, in which agency and communion are universal dimensions of well-being, and people in different cultures require different combinations of agency and communion to experience well-being. Following this theoretical development, the authors examine cultural impediments to the good life in individualistic and collectivistic cultures. The mutual incompatibility of agency and communion is ruled out as a possible cause of why it is so difficult to live the good life. Instead, the authors propose a dialectical synthesis of agency and communion as a way of dealing with this challenge of living the good life.     

Great Expectations: The Negative Consequences of Falling Short1

The present study shows conditions under which a positive stereotypic belief–Asians are good in mathematics–can have negative consequences. Participants graded a poorly performed mathematical assignment that they believed was the work of an Asian or a White target person. Under no accuracy instructions, participants who spent less time grading (unmotivated participants) assigned fewer points to the Asian than the White target. There was no difference in assignment of points to the Asian or the White target when participants were given accuracy instructions or spent more time grading (motivated participants). The findings suggest that group members may experience negative consequences when they fall short of “great expectations” stemming from a positive stereotypic belief about their group.     

河图洛书探源

河图洛书究竟为何物,历化学者解说大相径庭。本文主要就其汉以前的渊源作了初步探讨,提出它始见于先秦古籍,是某些企图改朝换代的“圣人”们的有意伪造之物,汉儒称其为八卦九畴并附会《周易》,宣扬灾异思想,汉代方士也假托河图洛书编纬图,主要内容是与“经天验道”、推算吉凶有关的卜筮数术,目的在于为改朝换代制造“天书”、“祥瑞”,以神话自已。     

“Celebrities to lean on!” Perceived celebrity support across two cultures—Iran and the United States

Though many people loathe celebrities and their lifestyles, celebrities can also be perceived as being available to provide community support. The purpose of this study was to establish the psychometric properties of the Perceived Celebrity Support Inventory. The scale was developed to capture three aspects of perceived celebrity support to the community: instrumental (i.e., providing tangible and concrete assistance), informational (i.e., advice, explanation, and information), and emotional (i.e., empathizing, encouraging, listening, and comforting) support. Factor and item analyses have revealed robust psychometric properties in samples drawn from the United States (US) and Iran. The US sample perceived higher community support from celebrities than the Iranian sample. In the Iranian sample, perceived celebrity support for the community was associated with more positive attitudes and less hatred of celebrity culture. In the US, perceived celebrity support was associated with negative attitudes and elevated hatred towards celebrities. The findings advance the literature by providing an instrument with which to measure positive aspects of celebrity influence across cultures.