A comparative effectiveness trial of functional behavioral assessment methods

Clinicians report primarily using functional behavioral assessment (FBA) methods that do not include functional analyses. However, studies examining the correspondence between functional analyses and other types of FBAs have produced inconsistent results. In addition, although functional analyses are considered the gold standard, their contribution toward successful treatment compared with other FBA methods remains unclear. This comparative effectiveness study, conducted with 57 young children with autism spectrum disorder, evaluated the results of FBAs that did (n = 26) and did not (n = 31) include a functional analysis. Results of FBAs with and without functional analyses showed modest correspondence. All participants who completed functional communication training achieved successful outcomes regardless of the type of FBA conducted.     

Velocity discrimination: reliability and construct validity in older adults

The aim of this study was to determine whether a test of velocity discrimination is a reliable and valid measure of proprioception in healthy older adults. Results revealed excellent test-retest reliability over a 2-week period. Velocity discrimination also indicated good construct validity with modest correlations with center of pressure sway outcomes in eyes open and closed conditions as well as stair climbing time. Good construct validity was identified by velocity discrimination sensitivity to age with a higher mean value for the older participants than for the younger participants. These findings suggest velocity discrimination is a valid and reliable measure of velocity sense, which may be included with measures of position and movement sense to enhance the proprioceptive testing repertoire among researchers. Implications of these results are discussed in terms of evaluation of proprioceptive training programs aimed to enhance postural control.     

Perceived Physical Attractiveness, Sexual History, and Sexual Intentions: An Internet Study

This study was designed to examine the influence a potential date’s physical attractiveness and sexual history has on an individual’s intentions to engage in safer sex. Over 1,200 participants completed an Internet survey. The questionnaire presented a randomized biography and photograph and asked participants to rate their interest in dating and having a sexual relationship with the target. Participants were randomly assigned to one of six conditions based on the target’s physical attractiveness (low vs. high) and sexual experience (low, medium, or high). Results indicated that men reported greater intentions to have sex than women did, and all participants reported greater likelihood of having sex when the potential partner was highly attractive. Participants rated men and more experienced targets as more risky sexual partners, and the level of a target’s sexual experience was directly related to participants’ willingness to discuss sexual risks. Results indicate a continuing need to include discussion of cognitive factors in all HIV prevention efforts.     

Rats (Rattus norvegicus) encode the shape of an array of discrete objects

To navigate efficiently, a traveler must establish a heading using a frame of reference. A large body of evidence has indicated that humans and a variety of nonhuman animals utilize the geometry, or shape, of enclosed spaces as a frame of reference to determine their heading. An important and yet unresolved question is whether shape information from arrays of discrete objects and enclosed environments are represented, and utilized, in the same way. In the present study, rats were presented with a reference memory task in which they had to find water that was hidden in 1 of 4 discrete and unique objects placed at the vertices of a rectangle. The results indicate that rats could utilize both feature and geometry cues to locate the hidden goal. The rats' performance declined during transformation tests using a triangular array, indicating that the rats may have encoded the primary axis of the object array, rather than local cues, to direct their search.     

Molecular Genetic Studies of Eating Disorders: Current Status and Future Directions

ABSTRACT— We review association studies that have examined the genetic basis of eating disorders. Overall, findings suggest that serotonin, brain-derived neurotrophic factor, and estrogen genes may be important for the development of the disorders. These neuronal systems influence behavioral and personality characteristics (e.g., anxiety, food intake) that are disrupted in eating disorders. Future studies would benefit from larger sample sizes and inclusion of behavioral and personality covariates in analyses. Consideration of the mechanisms of genetic effects and interactions between genes and environment is also needed to extend conceptualizations of the genetic basis of these disorders.     

The making of an analyst: from 'ideal' to 'good-enough'

This paper addresses the issue of variances in training modalities and how this is linked to one's personal experience of training and to one's analytic lineage. The author, who bases his reflections on discussions held during the yearly directors of training meeting of the North American Jungian Societies, suggests that, while each institute aims to provide an 'ideal' training programme for its candidates, the philosophy underlying how this ideal is defined depends, in large part, on the theoretical and philosophical orientation of the founding fathers and mothers. This results in a form of analytic lineage that necessarily impacts on the form and content of the 'ideal' programme. Shadow issues related to analytic lineage in the admissions procedures, case consultation, exam committees and review committees are presented. Motivation for why we choose to train and reflections on what makes an analyst 'Jungian' are explored.     

Effort-reward imbalance, overcommitment, and psychological distress in Canadian police officers

The purpose of the present study was to examine the relationship among Effort, Reward, and Overcommitment dimensions of Siegrist's Effort-Reward Imbalance Model and Psychological Distress in a sample of 78 Canadian police officers. Ages of respondents ranged between 24 and 56 years (M=36.1, SD=8.0). 30% of respondents had been in policing for 16 years or more, 24% between 6 and 15 years, and 44% for 5 years or less. Ordinary least-squares regression was used to evaluate the relationship between the independent and dependent variables. After adjusting for age, sex, education, and marital status, higher levels of Effort-Reward Imbalance and Overcommitment were associated with greater Psychological Distress. Present findings support the utility of the model in this particular occupational group and add to the increasing literature suggesting association of Effort-Reward Imbalance, Overcommitment, and reduced mental health.     

Increased brain serotonin turnover in panic disorder patients in the absence of a panic attack: reduction by a selective serotonin reuptake inhibitor

Since the brain neurotransmitter changes characterising panic disorder remain uncertain, we quantified brain noradrenaline and serotonin turnover in patients with panic disorder, in the absence of a panic attack. Thirty-four untreated patients with panic disorder and 24 matched healthy volunteers were studied. A novel method utilising internal jugular venous sampling, with thermodilution measurement of jugular blood flow, was used to directly quantify brain monoamine turnover, by measuring the overflow of noradrenaline and serotonin metabolites from the brain. Radiographic depiction of brain venous sinuses allowed differential venous sampling from cortical and subcortical regions. The relation of brain serotonin turnover to serotonin transporter genotype and panic disorder severity were evaluated, and the influence of an SSRI drug, citalopram, on serotonin turnover investigated. Brain noradrenaline turnover in panic disorder patients was similar to that in healthy subjects. In contrast, brain serotonin turnover, estimated from jugular venous overflow of the metabolite, 5-hydroxyindole acetic acid, was increased approximately 4-fold in subcortical brain regions and in the cerebral cortex (P < 0.01). Serotonin turnover was highest in patients with the most severe disease, was unrelated to serotonin transporter genotype, and was reduced by citalopram (P < 0.01). Normal brain noradrenaline turnover in panic disorder patients argues against primary importance of the locus coeruleus in this condition. The marked increase in serotonin turnover, in the absence of a panic attack, possibly represents an important underlying neurotransmitter substrate for the disorder, although this point remains uncertain. Support for this interpretation comes from the direct relationship which existed between serotonin turnover and illness severity, and the finding that SSRI administration reduced serotonin turnover. Serotonin transporter genotyping suggested that increased whole brain serotonin turnover most likely derived not from impaired serotonin reuptake, but from increased firing in serotonergic midbrain raphe neurons projecting to both subcortical brain regions and the cerebral cortex.