Mechanisms of source confusion and discounting in short-term priming: 1. Effects of prime duration and prime recognition

Huber, Shriffrin, Lyle, and Ruys (2001) measured short-term repetition priming effects in perceptual identification with two-alternative forced-choice testing. There was a preference to choose repeated words following passive viewing of primes and a preference against choosing repeated words following active responding to primes. In this present study, we explored conditions of prime processing that produce this pattern of results. Experiment 1 revealed that increased prime duration under passive viewing instructions produces the active priming pattern. Experiment 2 assessed memory for primes: With poor recognition of primes, there was a strong preference for repeated words; however, with good recognition of primes, this preference was eliminated. These results are modeled by a computational theory of optimal decision making, responding optimally with unknown sources of evidence (ROUSE). In ROUSE, a preference for repeated words results from source confusion between primes and choice words. A reversal in the direction of preference arises from the discounting of words known to have also appeared as primes.     

Mechanisms of source confusion and discounting in short-term priming 2: effects of prime similarity and target duration

D. E. Huber, R. M. Shiffrin, K. B. Lyle, and K. I. Ruys (2001) tested two-alternative, forced-choice (2-AFC) perceptual identification in a short-term priming task. For repetition priming, passive viewing of primes resulted in a preference to choose repeated words, but actively responding to primes resulted in a preference against choosing repeated words. These results were explained with a computational model, responding optimally with unknown sources of evidence (ROUSE), using the offsetting mechanisms of source confusion and discounting. An analysis of ROUSE revealed conditions under which discounting efficacy should diminish, causing a preference for primed words even with active prime processing. Two new studies confirm 2 such conditions: very short target flash durations and very low similarity between primes and primed choice words. These a priori predictions contrast with the a posteriori data fits of a multinomial model developed by R. Ratcliff and G. McKoon (2001).     

Spatial stimulus cue information supplying auditory saltation

Auditory saltation is a misperception of the spatial location of repetitive, transient stimuli. It arises when clicks at one location are followed in perfect temporal cadence by identical clicks at a second location. This report describes two psychophysical experiments designed to examine the sensitivity of auditory saltation to different stimulus cues for auditory spatial perception. Experiment 1 was a dichotic study in which six different six-click train stimuli were used to generate the saltation effect. Clicks lateralised by using interaural time differences and clicks lateralised by using interaural level differences produced equivalent saltation effects, confirming an earlier finding. Switching the stimulus cue from an interaural time difference to an interaural level difference (or the reverse) in mid train was inconsequential to the saltation illusion. Experiment 2 was a free-field study in which subjects rated the illusory motion generated by clicks emitted from two sound sources symmetrically disposed around the interaural axis, ie on the same cone of confusion in the auditory hemifield opposite one ear. Stimuli in such positions produce spatial location judgments that are based more heavily on monaural spectral information than on binaural computations. The free-field stimuli produced robust saltation. The data from both experiments are consistent with the view that auditory saltation can emerge from spatial processing, irrespective of the stimulus cue information used to determine click laterality or location.     

The effects of adult aging and induced positive and negative mood on planning

Changes in executive functions have been found in older adults and also in young adults experiencing positive or negative mood states. The current study investigated the hypothesis that older adults would show greater executive function impairment following mood induction than young adults. Ninety-six participants (half aged 19-37, half aged 53-80) completed a neutral, positive, or negative mood induction procedure, followed by the Tower of London planning task. Significant interactions were found between age and mood such that older adults showed greater planning impairment than young adults in both the positive and negative mood conditions. Emotionally salient events occurring before testing may interfere with executive function in older adults.     

Psychosocial Treatment Strategies in the MTA Study: Rationale, Methods, and Critical Issues in Design and Implementation

The Collaborative Multimodal Treatment Study of Children with Attention Deficit Hyperactivity Disorder (ADHD), the MTA, is the first multisite, cooperative agreement treatment study of children, and the largest psychiatric/psychological treatment trial ever conducted by the National Institute of Mental Health. It examines the effectiveness of Medication vs. Psychosocial treatment vs. their combination for treatment of ADHD and compares these experimental arms to each other and to routine community care. In a parallel group design, 579 (male and female) ADHD children, aged 7–9 years, 11 months, were randomly assigned to one of the four experimental arms, and then received 14 months of prescribed treatment (or community care) with periodic reassessments. After delineating the theoretical and empirical rationales for Psychosocial treatment of ADHD, we describe the MTA's Psychosocial Treatment strategy applied to all children in two of the four experimental arms (Psychosocial treatment alone; Combined treatment). Psychosocial treatment consisted of three major components: a Parent Training component, a two-part School Intervention component, and a child treatment component anchored in an intensive Summer Treatment Program. Components were selected based on evidence of treatment efficacy and because they address comprehensive symptom targets, settings, comorbidities, and functional domains. We delineate key conceptual and logistical issues faced by clinical researchers in design and implementation of Psychosocial research with examples of how these issues were addressed in the MTA study.Deceased     

Family Processes and Treatment Outcome in the MTA: Negative/Ineffective Parenting Practices in Relation to Multimodal Treatment

To elucidate processes underlying therapeutic change in a large-scale randomized clinical trial, we examined whether alterations in self-reported parenting practices were associated with the effects of behavioral, medication, or combination treatments on teacher-reported outcomes (disruptive behavior, social skills, internalizing symptoms) in children with attention-deficit hyperactivity disorder (ADHD). Participants were 579 children with Combined-type ADHD, aged 7–9.9 years, in the Multimodal Treatment Study of Children with ADHD (MTA). We uncovered 2 second-order factors of parenting practices, entitled Positive Involvement and Negative/Ineffective Discipline. Although Positive Involvement was not associated with amelioration of the school-based outcome measures, reductions in Negative/Ineffective Discipline mediated improvement in children's social skills at school. For families showing the greatest reductions in Negative/Ineffective Discipline, effects of combined medication plus behavioral treatment were pronounced in relation to regular community care. Furthermore, only in combination treatment (and not in behavioral treatment alone) was decreased Negative/Ineffective Discipline associated with reduction in children's disruptive behavior at school. Here, children in families receiving combination treatment who showed the greatest reductions in Negative/Ineffective Discipline had teacher-reported disruptive behavior that was essentially normalized. Overall, the success of combination treatment for important school-related outcomes appears related to reductions in negative and ineffective parenting practices at home; we discuss problems in interpreting the temporal sequencing of such process-outcome linkages and the means by which multimodal treatment may be mediated by psychosocial processes related to parenting.     

Parenting and Family Stress Treatment Outcomes in Attention Deficit Hyperactivity Disorder (ADHD): An Empirical Analysis in the MTA Study

Parenting and family stress treatment outcomes in the MTA study were examined. Male and female (579), 7–9-year-old children with combined type Attention Deficit Hyperactivity Disorder (ADHD), were recruited at six sites around the United States and Canada, and randomly assigned to one of four groups: intensive, multi-faceted behavior therapy program alone (Beh); carefully titrated and monitored medication management strategy alone (MedMgt); a well-integrated combination of the two (Comb); or a community comparison group (CC). Treatment occurred over 14 months, and assessments were taken at baseline, 3, 9, and 14 months. Parenting behavior and family stress were assessed using parent-report and child-report inventories. Results showed that Beh alone, MedMgt alone, and Comb produced significantly greater decreases in a parent-rated measure of negative parenting, Negative/Ineffective Discipline, than did standard community treatment. The three MTA treatments did not differ significantly from each other on this domain. No differences were noted among the four groups on positive parenting or on family stress variables. Results are discussed in terms of the theoretical and empirically documented importance of negative parenting in the symptoms, comorbidities and long-term outcomes of ADHD.     

Age-related differences in semantic priming: evidence from event-related brain potentials

Hasher and Zacks (1988) suggested that aging may affect processes involved in the inhibition of irrelevant information during language processing. Our experiment tested this hypothesis using the N400 event-related brain potential in a priming paradigm and assessed whether older subjects could benefit from the constraints of a sentence context. Twenty older (63 to 88 years) and 20 young (19 to 29 years) subjects read sentences and word pairs. Each final word varied on the degree of relatedness to the preceding context, with some being highly related (BC), moderately related (R), or unrelated (U). Younger subjects showed the expected N400 effect gradient (U > R > BC) in both the sentence and word-pair contexts, while older adults showed no discrimination between the conditions (U = R = BC) for the sentence and limited discrimination (U > BC) for the word pairs. These results support the inhibition-deficit hypothesis, whereby older adults fail to inhibit related items in working memory, and suggest that older adults do not benefit from the constraints of a sentence context.